FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Ianelli Christopher		 2. Issuer Name and Ticker or Trading Symbol

iSpecimen Inc. [ ISPC ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
_____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle)

C/O ISPECIMEN INC., 450 BEDFORD STREET		 3. Date of Earliest Transaction (MM/DD/YYYY)

10/24/2022
(Street)

LEXINGTON, MA 02420
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock (1)10/24/2022  J(1)  18229 D (2)424514 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Option  (3)10/24/2022 10/24/2022 J     564   (3)10/24/2022 Common Stock 564  (3)845 D  
Explanation of Responses:
(1) Pursuant to certain separation agreement, dated October 24, 2022, by and between the issuer and the reporting person, (i) an aggregate of 13,021 restricted stock units of the issuer (the "RSUs"), which were previously awarded to the reporting person but not settled, were settled at an accelerated vesting schedule and as a result, 13,021 shares of common stock were issued to the reporting person; and (ii) 18,229 RSUs, which were previously awarded to the reporting person and not settled, were forfeited.
(2) The RSUs were previously awarded as compensation to the reporting person for his former service as an officer of the issuer.
(3) Represents unvested stock options that were forfeited upon the termination of employment of the reporting person with the issuer. Stock options exercisable for an aggregate of 845 shares that were vested on the date of termination of employment of the reporting person will expire on January 22, 2023, if not exercised by the reporting person before that date.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Ianelli Christopher
C/O ISPECIMEN INC.
450 BEDFORD STREET
LEXINGTON, MA 02420		X
Signatures
/s/ Christopher Ianelli11/14/2022
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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