SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 


 

FORM 6-K

 

 

REPORT OF FOREIGN PRIVATE ISSUER

Pursuant to Rule 13a-16 or 15d-16 of

the Securities Exchange Act of 1934

 

21 December 2007

 

PROTHERICS PLC

(Translation of Registrant’s Name Into English)

 

 

The Heath Business & Technical Park
Runcorn, Cheshire, W47 4QF England

(Address of Principal Executive Offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

 

Form 20-F       X              Form 40-F               

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):             

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 191(b)(7):             

 

Indicate by check mark whether the registrant by furnishing the information contained in this form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

 

Yes                     No          X     

 

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82-              .

 

 

The Registrant is furnishing a copy of its announcements as reported to the Company Announcements Office of the London Stock Exchange.

 

 

 

 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

       

 

PROTHERICS PLC

       

Date: (Date)

 

By:

 

/s/ Rolf Soderstrom


       

Rolf Soderstrom

       

Finance Director

 

 

Protherics PLC

 

Notification of Major Interests in Shares


 

London, UK; Brentwood, TN, US: 21 December 2007 - Protherics PLC (“Protherics” or the “Company”), the international biopharmaceutical company focused on critical care and cancer, announces that on 20 December 2007, in accordance with the Transparency Obligations Directive, a notification of interest in the ordinary share capital of the Company was received from AXA Investment Managers UK Limited on behalf of AXA S.A. and its Group Companies (“AXA”). The notification follows an increase in the Indirect holding of AXA. Details of the interest notified are as follows:
 

 

1.     Reason for the notification (please tick the appropriate box or boxes)

 

 


An acquisition of voting rights

 

X

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached


 


An event changing the breakdown of voting rights


 


Other (please specify):


 

2. Full name of person(s) subject to the notification obligation:

AXA S.A., 25 Avenue Matignon, 75008 Paris and its group of companies.

3. Full name of shareholder(s) (if different from 2.):

 

 

4. Date of the transaction (and date on which the threshold is crossed or reached if different):

18 December 2007

5. Date on which issuer notified:

19 December 2007

6. Threshold(s) that is/are crossed or reached:

14%

7. Notified details:

     


 

A: Voting rights attached to shares

Class/type of shares

if possible using the ISIN CODE

Situation previous to the Triggering transaction

Resulting situation after the triggering transaction

Number of Shares

Number of Voting Rights

Number of shares

Number of voting rights

% of voting rights

 

Direct

Direct

Indirect

Direct

Indirect

 

0702920

 

 

43,726,012

 

43,726,012

 

741,666

 

741,666

 

 

48,854,003

 

0.22%

 

14.36%



 

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ Conversion Period/ Date

Number of voting rights that may be acquired if the instrument is exercised/ converted.

% of voting rights

 

 

 

 

 

 

 

 

 

 

 

Total (A+B)

Number of voting rights

% of voting rights

 

49,595,669

 

14.58%



 

8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable :

Name of Company/Fund

 

Number of Shares

% of issued share capital

AXA UK Investment Co ICVC

UK Smaller Companies Fund

Indirect

551,929

 

0.16224

 

Sun Life Pensions Management Ltd

Direct

25,000

 

0.00735

 

Sun Life Unit Assurance Ltd

FTSE All Share Tracker

Direct

53,913

 

0.01585

 

Sun Life Pensions Management

FTSE All Share Tracker

Direct

294,874

 

0.08668

 

AXA Framlington

SEI UK Equity

Indirect

750,000

 

0.22046

 

AXA Framlington

St James Place Exempt (Pens) Fund

Indirect

1,600,000

 

0.47031

 

AXA Framlington

St James Place Net (Life) Fund

Indirect

 

1,800,000

 

0.52910

 

AXA Framlington

St James Place Offshore Fund

Indirect

400,000

 

0.11758

 

AXA Framlington

Daimler Chrysler

Indirect

600,000

 

0.17637

 

AXA Framlington

Throgmorton Trust

Indirect

3,120,333

 

0.91720

 

AXA Framlington

UK Select Ops

Indirect

15,013,453

 

4.41308

 

AXA Framlington

Equity Income

Indirect

13,753,131

 

4.04262

 

AXA Framlington

Managed Balanced

Indirect

2,000,000

 

0.58788

 

AXA Framlington

UK Smaller Companies

Indirect

1,500,000

 

0.44091

 

AXA Framlington

BAE Systems Pensions Fund CIF Trustees

Indirect

500,000

 

0.14697

 

AXA Framlington

BAE Systems 2000 Pensions Fund

Indirect

220,000

 

0.06467

 

Framlington onshore private clients

Indirect

6,820,157

 

2.00473

 

Axa Sun Life With Profits Passive

Direct

226,817

 

0.06667

 

Sun Life Ass With Profits Passive

Direct

141,062

 

0.04146

 

AXA Framlington

St James Place Internal Equity & Income UT

Indirect

 

225,000

 

 

0.06614

 

 

Total Direct

Total Indirect

 

741,666

48,854,003

 

 

0.21801

14.36024

 

 

TOTAL

 

49,595,669

 

 

14.57825

 

 

Proxy Voting:

9. Name of the proxy holder:

 

10. Number of voting rights proxy holder will cease to hold:

 

11. Date on which proxy holder will cease to hold voting rights:

 

           


 

12. Additional information:

 

 

 



 

| Ends |

 

For further information please contact:

 

Protherics

 

Nick Staples, Director of Corporate Affairs

+44 (0) 7919 480510

Julie Vickers, Company Secretary

+44 (0)1928 518010

 

 

Financial Dynamics – press enquiries

 

London: Ben Atwell, Lara Mott

+44 (0) 20 7831 3113

New York: John Capodanno, Jonathan Birt

+1 212 850 5600



 

Or visit www.protherics.com

END

 

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