Impact Biomedical, Inc., a wholly owned subsidiary of Document
Security Systems, Inc. (NYSE American: DSS), along with its
scientific research partner Global Research and Discovery Group
Sciences, GRDG, announced today encouraging results from clinical
tests of its 3FDB (“DEET Booster”) technology. These results
suggest that 3FDB can boost the effectiveness of mosquito
repellants, specifically DEET.
Daryl Thompson, Director of Scientific Initiatives at GRDG,
stated, “These tests represent an important development in
addressing mosquito borne diseases and could signal a new frontier
of protection strategies.”
Mosquitos, host to a variety of diseases, including Yellow
Fever, West Nile, malaria, dengue, Zika and others, are responsible
for more than one million deaths worldwide annually, according to
the National Institutes of Health. Working with an independent lab,
GRDG conducted three tests involving the mosquito (Aedes
aegypti).
First Test:The first test examined 3FDB / DEET
concentrations (1% 3FDB with 0.5% DEET) that could be suitable for
use in fragrances, shampoos, soaps, and detergents. The mixture was
tested against an untreated control group and a group treated with
DEET (0.5%) alone over three-, five-, and eight-hour periods.
The lower concentration mixture outperformed DEET alone. After
three hours, the lower concentration mixture had a 74% repellency
rate, while the DEET alone had a repellency rate of 38%. After 5
hours, the 3FDB mixture had a repellency rate of 39%, compared to
22% for DEET alone. After 8 hours, the 3FDB mixture scored a
repellency rate of 47%, compared to 15% for DEET alone.
“As was observed from these tests, adding the 3FDB/DEET mixture
to everyday household items increased the protection against
mosquito bites over various periods of time,” said Thompson. “The
creative application of this type of technology allows for new,
unobtrusive ways to repel mosquitos.”
Second TestA second test comparing shirt fabric
impregnated with 3FDB and untreated shirt fabric, demonstrated that
3FDB impregnated fabric provides better protection compared to
untreated fabric. After 15 minutes, the 3FDB fabric repelled 93% of
mosquito landings, while the untreated fabric repelled only 14%.
The impregnated fabric stopped 100% of the probes, compared to 17%
for the untreated fabric. Probes occur when a mosquito finds a host
and probes for a blood vessel. In fact, throughout the testing,
which included measurements after six hours and eight hours, the
3FDB impregnated fabric continued to repel 100% of mosquito probes.
The untreated fabric only repelled 14% of landings and 12% of
probes after six hours. After eight hours, the untreated fabric
scored negative percentages, which represented an increase in
activity. In other words, after eight hours, the untreated fabric
seemed to attract mosquitos instead of providing protection.
Third TestThe final test tested higher
concentrations of 3FDB for a longer duration. A mixture of 10% 3FDB
with 5% DEET appeared to increase the effectiveness of 5% DEET
alone at the 3-, 5-, 8-, 12-, 15-, and 18-hour marks. After three
hours, the 3FDB / DEET mixture had a repellency rate of 98%,
compared to 85% for DEET alone. After eight hours, the 3FDB mixture
had a repellency rate of 95%, compared to 62% for DEET alone. After
18 hours, the 3FDB mixture remained strong, having a repellency
rate of 78%, compared to 53% for DEET alone.
GRDG Chief Scientific Advisor Dr. Roscoe M. Moore, Jr., United
States Assistant Surgeon General (Retired) and former Epidemic
Intelligence Service (EIS) Officer at the U.S. Centers for Disease
Control and Prevention said that he believes these tests are
encouraging. “The flexibility of the 3F technology allows us to
rethink our strategy in the fight against the transmission of
disease via mosquito,” he said.
About 3F TechnologyThe desire to lower the
number of mosquito-borne diseases around the world led GRDG to
study orchids from around the world before concentrating on the
Florida Everglades and the elusive ghost orchid, which produced a
chemical that inhibited the mosquito’s ability to find them. The
GRDG team was able to identify and, eventually, reproduce those
chemical compounds.
“These test results are the product of a creative process that
focuses on real-world problems and provides safe, real-world
solutions,” said Frank Heuszel, President of Impact Biomedical,
Inc. “We will continue to make unique products from botanical
sources that serve consumers in their everyday lives.”
In June 2021, Impact Biomedical and GRDG announced it had
received a U.S. Patent for 3FDB (US 10,966,424), a Functional
Fragrance Formulation, that increases the effectiveness of current
mosquito repellants through a light and delightfully fragrant
compound derived from botanical oils.
Thomas Meyer, Vice President, Innovation & Sustainability at
Chemia Corporation, the fragrance company that has exclusively
partnered with GRDG to formulate 3F-Fragrances, believes this will
change the personal care market. “Major brands will integrate this
technology into everyday products,” he said.
About Impact BioMedical, Inc.Impact BioMedical,
Inc. ("Impact BioMedical") is a wholly owned subsidiary of DSS and
a unique technology source, developer, and business partner in
addressing unmet needs in human healthcare and wellness. For more
information on Impact BioMedical visit http://impbio.com/.
About Document Security Systems, Inc.DSS is a
multinational company operating business segments in blockchain
security, direct marketing, healthcare, consumer packaging, real
estate, renewable energy, and securitized digital assets. Its
business model is based on a distribution sharing system in which
shareholders will receive shares in its subsidiaries as DSS
strategically spins them out into IPOs. Its historic business
revolves around counterfeit deterrent and authentication
technologies, smart packaging, and consumer product engagement. DSS
is led by its Chairman, Mr. Fai Chan, a highly successful global
business veteran of more than 40 years specializing in corporate
transformation while managing risk. He has successfully
restructured more than 35 corporations with a combined value of $25
billion.
For more information on DSS visit
http://www.dsssecure.com.
Investor Contact:Dave Gentry, CEORedChip Companies
Inc.407-491-4498Dave@redchip.com
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