Dr. Reddy’s Announces the USFDA Approval of Fondaparinux Sodium Injection
July 13 2011 - 1:53AM
Business Wire
Dr. Reddy’s Laboratories (NYSE: RDY) and Alchemia Limited,
Brisbane, Australia (ASX: ACL) announced today that Dr. Reddy’s has
received final approval of Dr. Reddy’s ANDA for Fondaparinux
Sodium Injection, a bioequivalent generic version of
Arixtra®*, in the US market on July 11, 2011 by the United
States Food & Drug Administration (USFDA). The approval covers
2.5 mg/ 0.5 mL, 5.0 mg/ 0.4 mL, 7.5 mg/ 0.6 mL and 10 mg/ 0.8 mL
doses of the drug in prefilled color-coded, single-dose syringes
with automatic needle safety device. Dr. Reddy’s will manufacture
fondaparinux under license using a patented process developed by
Alchemia.
Commenting on the approval, G.V. Prasad, Vice-Chairman and CEO
of Dr. Reddy’s, said, “The fondaparinux approval demonstrates the
strong technical capabilities of the teams at Dr. Reddy’s and
Alchemia. Given that this is a complex generic molecule which is
difficult to manufacture at scale, competition is likely to be
limited for the foreseeable future. Accordingly, from a commercial
perspective, Dr. Reddy’s will promptly execute a phased launch that
initially plays to our strengths in select wholesale and retail
outlets, and subsequently enhance share over time in the coming
quarters to augment the growing annuity of upsides in our North
America Generics business.”
Pete Smith, CEO of Alchemia, said, “This collaboration has
succeeded due to the expertise, dedication, and close communication
between the teams at both companies. This approval is a major
milestone for Alchemia, fondaparinux representing a significant
source of potential future income for the Company."
The US patents on Arixtra expired in 2002, the year before the
drug was launched in the US. Alchemia’s process for the synthesis
of fondaparinux is covered by a patent estate with two issued
patents and two pending applications in the US. Arixtra® brand had
U.S. sales of approximately $340 million (Y-o-Y growth of 16%) for
the 12 months ending May 2011.**
*Arixtra® is a registered trademark of Glaxo Group
Limited.**IMS National Sales Perspectives: Retail and Non-Retail
MAT MAY 2011
Disclaimer
This press release includes forward-looking statements, as
defined in the U.S. Private Securities Litigation Reform Act of
1995. We have based these forward-looking statements on our current
expectations and projections about future events. Such statements
involve known and unknown risks, uncertainties and other factors
that may cause actual results to differ materially. Such factors
include, but are not limited to, changes in local and global
economic conditions, our ability to successfully implement our
strategy, the market acceptance of and demand for our products, our
growth and expansion, technological change and our exposure to
market risks. By their nature, these expectations and projections
are only estimates and could be materially different from actual
results in the future.
About Dr. Reddy’s
Dr. Reddy’s Laboratories Ltd. (NYSE: RDY) is an integrated
global pharmaceutical company, committed to providing affordable
and innovative medicines for healthier lives. Through its three
businesses - Pharmaceutical Services and Active Ingredients, Global
Generics and Proprietary Products – Dr. Reddy’s offers a portfolio
of products and services including APIs, custom pharmaceutical
services, generics, biosimilars, differentiated formulations and
NCEs. Therapeutic focus is on gastro-intestinal, cardiovascular,
diabetes, oncology, pain management, anti-infective and pediatrics.
Major markets include India, USA, Russia and CIS, Germany, UK,
Venezuela, S. Africa, Romania, and New Zealand. For more
information, log on to: www.drreddys.com.
About Alchemia Limited
Alchemia is a drug discovery and development company founded on
its chemistry expertise. The Company’s lead program is fondaparinux
(a generic version of GlaxoSmithKline’s Arixtra®). Alchemia’s
pipeline of assets is built on two platform technologies: HyACT®
(targeted cancer delivery) and VAST® (drug discovery).
www.alchemia.com.au
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