Adolor Corporation (Nasdaq:ADLR) today announced that Michael R. Dougherty, President and Chief Executive Officer, will present at the 27th Annual J. P. Morgan Healthcare Conference on Thursday, January 15, 2009 at Noon Pacific Time (3:00 P.M. Eastern Time). The conference is being held at the Westin St. Francis Hotel in San Francisco, California.

Adolor�s presentation will be webcast live for investors through www.adolor.com and available for a period of 14 days following the conference.

About Adolor Corporation

Adolor Corporation is a biopharmaceutical company specializing in the discovery, development and commercialization of novel prescription pain management products.

Adolor�s first approved product in the United States is ENTEREG�, which is indicated to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. ENTEREG is available for short-term use in hospitals registered under the ENTEREG Access Support and Education (E.A.S.E.TM) Program. In collaboration with GlaxoSmithKline, the company launched ENTEREG in mid-2008.

For more information, visit www.adolor.com.

This press release is available on the website http://www.adolor.com.

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