Affymetrix Selected to Genotype More Than 9,000 Framingham Heart Study Samples; SHARE Project to Help Identify Genetic Variants
September 05 2006 - 8:01AM
Business Wire
Affymetrix Inc. (Nasdaq:AFFX) announced today that it has been
selected by the SHARE (SNP Health Association REsource) project for
a large-scale whole-genome association study. As part of the
project, Affymetrix will collaborate with the National Heart, Lung,
and Blood Institute (NHLBI) and the National Center for
Biotechnology Information (NCBI) of the National Institutes of
Health to identify genetic variants associated with heart, lung,
blood and sleep disorders. The SHARE project will analyze more than
9,000 samples collected by the NHLBI and Boston University for the
Framingham Heart Study. Clinicians have been using the Framingham
Heart Study to track and measure data relating to cardiovascular
disease since 1948. Data has been collected from more than 15,000
samples spanning three generations of individuals. For more
information on the Framingham Heart Study, please visit:
http://www.nhlbi.nih.gov/about/framingham/index.html "The
Framingham Heart Study is one of the most recognized clinical
research projects in history and we are honored that the NHLBI has
entrusted the genotyping of these valuable samples to Affymetrix,"
said Giulia C. Kennedy, Ph.D., senior director of genomics
collaborations at Affymetrix. "Researchers have been waiting for
decades for the right technology to come along and extract the
genetic information contained in these samples. When this project
is complete, researchers around the globe will have access to one
of the richest medical datasets in existence." The Affymetrix 500K
Array is making it possible for researchers to conduct these types
of large-scale whole-genome association studies today. The array
offers a comprehensive view of the genome, enabling researchers to
analyze 500,000 markers simultaneously and perform whole-genome
analyses in large populations. Affymetrix scientists will provide
the genotyping services. The company provides high quality
genotyping services for large projects, such as the 15,000 sample
study with the Wellcome Trust Case Control Consortium. As part of
the SHARE project, researchers will develop a data resource that
will integrate genome-wide genotypic information with phenotypic
information from multiple NHLBI studies. The data will be available
to the scientific community for further genome-wide association
analyses and will complement the data included in the recently
announced Affymetrix Control Program. "The SHARE project is
extremely important and Affymetrix is excited to offer the
genotyping technology and services," said Gregory Marcus, Ph.D.,
senior product manager at Affymetrix. "Our technology is making
these large-scale studies possible and affordable today. After this
project is completed, researchers will be able to run complementary
data sets that can be used in conjunction with the data from the
Framingham Heart Study." About Affymetrix Affymetrix scientists
invented the world's first high-density microarray in 1989 and
began selling the first commercial microarray in 1994. Since then,
Affymetrix GeneChip(R) technology has become the industry standard
in molecular biology research. Affymetrix technology is used by the
world's top pharmaceutical, diagnostic and biotechnology companies
as well as leading academic, government and not-for-profit research
institutes. More than 1,400 systems have been installed around the
world and more than 7,000 peer-reviewed papers have been published
using the technology. Affymetrix' patented photolithographic
manufacturing process provides the most information capacity
available today on an array, enabling researchers to use a
whole-genome approach to analyzing the relationship between
genetics and health. Affymetrix is headquartered in Santa Clara,
Calif., with manufacturing facilities in Sacramento, Calif., and
Bedford, Mass. The company maintains important sales and marketing
operations in Europe and Asia and has about 1,100 employees
worldwide. For more information about Affymetrix, please visit the
company's website at www.affymetrix.com. All statements in this
press release that are not historical are "forward-looking
statements" within the meaning of Section 21E of the Securities
Exchange Act as amended, including statements regarding Affymetrix'
"expectations," "beliefs," "hopes," "intentions," "strategies," or
the like. Such statements are subject to risks and uncertainties
that could cause actual results to differ materially for Affymetrix
from those projected, including, but not limited to: risks and
uncertainties associated with the agreement with the SHARE project
discussed in this press release; risks of the Company's ability to
achieve and sustain higher levels of revenue, higher gross margins,
reduced operating expenses; uncertainties relating to technological
approaches, manufacturing, product development; personnel
retention; uncertainties related to cost and pricing of Affymetrix
products; dependence on collaborative partners; uncertainties
relating to sole source suppliers; uncertainties relating to FDA
and other regulatory approvals; competition; risks relating to
intellectual property of others and the uncertainties of patent
protection and litigation. These and other risk factors are
discussed in Affymetrix' Form 10-K/A for the year ended December
31, 2005, and other SEC reports, including its Quarterly Reports on
Form 10-Q for subsequent quarterly periods. Affymetrix expressly
disclaims any obligation or undertaking to release publicly any
updates or revisions to any forward-looking statements contained
herein to reflect any change in Affymetrix' expectations with
regard thereto or any change in events, conditions or circumstances
on which any such statements are based. NOTE: Affymetrix, the
Affymetrix logo, and GeneChip are registered trademarks owned or
used by Affymetrix Inc.
Affymetrix (NASDAQ:AFFX)
Historical Stock Chart
From Jun 2024 to Jul 2024
Affymetrix (NASDAQ:AFFX)
Historical Stock Chart
From Jul 2023 to Jul 2024