FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Wood Gavin

2. Date of Event Requiring Statement (MM/DD/YYYY)
5/20/2013 

3. Issuer Name and Ticker or Trading Symbol

AFFYMETRIX INC [AFFX]

(Last)        (First)        (Middle)

C/O AFFYMETRIX, INC., 3420 CENTRAL EXPRESSWAY

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
___ X ___ Officer (give title below)          _____ Other (specify below)
Chief Financial Officer /

(Street)

SANTA CLARA, CA 95051       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4) 		2. Amount of Securities Beneficially Owned
(Instr. 4) 		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5) 		4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock   16412   (1) D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4) 		2. Date Exercisable and Expiration Date
(MM/DD/YYYY) 		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4) 		4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5) 		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Option to Purchase Common Stock     (2) 11/29/2013   Common Stock   4200   $24.66   D    
Option to Purchase Common Stock     (3) 6/6/2014   Common Stock   600   $25.71   D    
Option to Purchase Common Stock     (4) 6/23/2015   Common Stock   4200   $10.29   D    
Option to Purchase Common Stock     (5) 8/21/2015   Common Stock   2000   $8.71   D    
Option to Purchase Common Stock     (6) 2/19/2016   Common Stock   5000   $2.97   D    
Option to Purchase Common Stock     (7) 8/20/2016   Comon Stock   6000   $8.29   D    
Option to Purchase Common Stock     (8) 8/19/2017   Common Stock   4900   $4.22   D    
Option to Purchase Common Stock     (9) 2/17/2018   Common Stock   5200   $5.31   D    
Option to Purchase Common Stock     (10) 11/17/2018   Common Stock   4000   $4.85   D    
Option to Purchase Common Stock     (11) 7/26/2019   Common Stock   5000   $4.16   D    
Option to Purchase Common Stock     (12) 8/30/2019   Common Stock   5000   $3.91   D    
Option to Purchase Common Stock     (13) 2/7/2020   Common Stock   8000   $3.77   D    
Option to Purchase Common Stock     (13) 2/7/2020   Common Stock   22000   $3.77   D    

Explanation of Responses:
( 1)  Includes the following restricted stock units ("RSUs"), each of which vests in equal anual installments over four years from the grant date, less the number of shares withheld for tax purposes on subsequent scheduled vesting date(s) on or before May 20, 2013 ("Shares Withheld"): (1) 1,225 RSUs granted on August 19, 2010 less 289 Shares Withheld, (2) 1,400 RSUs granted on February 17, 2011 less 294 Shares Withheld, (3) 6,000 RSUs granted on November 17, 2011 less 630 Shares Withheld, (4) 1,500 RSUs granted on July 26, 2012, (5) 1,500 RSUs granted on Augst 30, 2012 and (6) 6,000 RSUs granted on February 7, 2013.
( 2)  Stock option becomes exercisable in equal annual installments over four years from the grant date of November 29, 2006.
( 3)  Stock option becomes exercisable in equal annual installments over four years from the grant date of June 6, 2007.
( 4)  Stock option becomes exercisable in equal annual installments over four years from the grant date of June 23, 2008.
( 5)  Stock option becomes exercisable in equal annual installments over four years from the grant date of August 21, 2008.
( 6)  Stock option becomes exercisable in equal annual installments over four years from the grant date of February 19, 2009.
( 7)  Stock option becomes exercisable in equal annual installments over four years from the grant date of August 20, 2009.
( 8)  Stock option becomes exercisable in equal annual installments over four years from the grant date of August 19, 2010.
( 9)  Stock option becomes exercisable in equal annual installments over four years from the grant date of February 17, 2011.
( 10)  Stock option becomes exercisable in equal annual installments over four years from the grant date of November 17, 2011.
( 11)  Stock option becomes exercisable in equal annual installments over four years from the grant date of July 26, 2012.
( 12)  Stock option becomes exercisable in equal annual installments over four years from the grant date of August 30, 2012.
( 13)  Stock option becomes exercisable in equal annual installments over four years from the grant date of February 7, 2013.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Wood Gavin
C/O AFFYMETRIX, INC.
3420 CENTRAL EXPRESSWAY
SANTA CLARA, CA 95051

Chief Financial Officer

Signatures
/s/ Siang H. Chin, Attorney-in-Fact for Gavin Wood 5/30/2013
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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