FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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OMB Number: 3235-0287
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Le Thong Q.		 2. Issuer Name and Ticker or Trading Symbol

ALSP Orchid Acquisition Corp I [ ALOR ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    __X__ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chief Executive Officer
(Last)          (First)          (Middle)

C/O ALSP ORCHID ACQUISITION CORP I, 2815 EASTLAKE AVENUE EAST, SUITE 300		 3. Date of Earliest Transaction (MM/DD/YYYY)

11/22/2021
(Street)

SEATTLE, WA 98102
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Class A Ordinary Shares 11/22/2021  P  825000 A$10.00 (1)825000 I By ALSP Orchid Sponsor LLC (2)
Class A Ordinary Shares 11/23/2021  P  90000 A$10.00 (1)915000 I By ALSP Orchid Sponsor LLC (2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
(1) The reported Class A Ordinary Shares and warrants were purchased by ALSP Orchid Sponsor LLC in connection with a private placement offering of the Issuer. ASLP Orchid Sponsor LLC paid $10.00 for each private placement unit purchased. Each private placement unit consisted of one Class A Ordinary Share of the Issuer and one half of one warrant, with each whole warrant entitling the holder to purchase one Class A Ordinary Share at $11.50 per share.
(2) The securities reported herein are held of record by ALSP Orchid Sponsor LLC. Thong Q. Le and Ian A.W. Howes are the managers of ALSP Orchid Sponsor LLC, and as such, have voting and investment discretion with respect to the securities held by ALSP Orchid Sponsor LLC. Messrs. Le and Howes disclaim beneficial ownership over such shares except to the extent of their pecuniary interest therein.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Le Thong Q.
C/O ALSP ORCHID ACQUISITION CORP I
2815 EASTLAKE AVENUE EAST, SUITE 300
SEATTLE, WA 98102		XXChief Executive Officer
Howes Ian
C/O ALSP ORCHID ACQUISITION CORP I
2815 EASTLAKE AVENUE EAST, SUITE 300
SEATTLE, WA 98102		XXChief Financial Officer
ALSP Orchid Sponsor LLC
2815 EASTLAKE AVENUE EAST, SUITE 300
SEATTLE, WA 98102
X
Signatures
/s/ Thong Q. Le3/18/2022
**Signature of Reporting PersonDate

/s/ Ian A.W. Howes3/18/2022
**Signature of Reporting PersonDate

/s/ Thong Q. Le, Manager of ALSP Orchid Sponsor LLC3/18/2022
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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