JRoon71
3 hours ago
Yes, he controls all of the funds (not "owns"). Each fund is an independent business entity (he obviously owns shares in some or all of the funds, but that is different than "owning" the fund itself). So there is no wash sale issue. But because Denner has effective control over the funds (NOT ownership, but CONTROL), they are all reported aggregately. He's got 6 or 7 different funds that he runs (under the purview of the SEC - no idea what he has outside of the U.S.).
It's also possible that he shifts funds between US-based funds and offshore funds, which would explain why shares mysteriously disappear and re-appear, while supposedly "never selling a single share". This would likely avoid tax harvesting/wash sale rules.
Not sure how all that works with these hedge fund type things. But if I have two accounts, and sell a stock in one creating a loss, but immediately (with 30 days either way) repurchase the stock in another account, the IRS considers that a wash sale and I don't get the benefit of claiming a loss on the sold shares. So not sure how Denner works this. Does he not own the other accounts?
JRoon71
3 hours ago
His shares also "re-appeared" (likely from a fund that was outside the purview of the SEC). This is basically another situation where he has moved shares around among his various funds. When he exits one fund, he effectively "sells" them (recording a tax loss), and then when they are acquired in the new fund, he establishes a new cost basis at the price at the time of the transaction.
But since he neither gave up effective control of the shares, nor added or deleted shares, no filing was required.
How did he get his average down to 1.29? He would have to file any transactions within 3 days. There were no trades.
CaptBeer
1 day ago
More from the article:
$AMRN https://www.sciencedirect.com/science/article/pii/S2452302X24003735
Dr. Deepak Bhatt:
Inflammation contributes centrally to the genesis of plaque rupture and ischemic events. Contemporary data support that the risk associated with arterial inflammation persists independently of low-density lipoprotein cholesterol and triglyceride levels.9 The data from Reilly et al6 suggest that EPA could help address this component of residual cardiovascular risk. Analyses from REDUCE-IT show consistent clinical benefits of EPA across baseline levels of low-density lipoprotein cholesterol (and triglycerides, as noted in the previous text). Anti-inflammatory effects mediated by the adaptive immune modulation beyond those assessed by the biomarkers of innate immunity previously reported in REDUCE-IT, such as the effects on T cells reported by Reilly et al,6 could contribute to these benefits.
The valuable data from Reilly et al6 add to other important experimental data that have shown cell membrane stabilizing properties, other anti-inflammatory effects, antioxidant benefits, and antithrombotic properties of EPA, beyond its ability to lower levels of triglyceride-rich lipoproteins.8 These laboratory data complement several randomized imaging trials that also show effects of EPA on slowing or even reversing coronary plaque progression, including the first demonstration of an effect of any drug on improving noninvasively determined fractional flow reserve on CT angiography.10
The present analysis should prompt further research on EPA. This molecule, highly conserved through evolution, appears to play a fundamental role in cardiovascular biology. In REDUCE-IT, no apparent excess in infections emerged; thus, unlike some other targeted anti-inflammatory agents, there does not appear to be an infectious disease risk associated with EPA. This observation opens the door to the study of EPA in other disease states where the effects described by Reilly et al6 on T cells may also provide clinical benefit.
lizzy241
1 day ago
The deals are out there, M&A is picking up. Amarin is next!
Merck buys rights to heart disease drug in latest China deal
REUTERS 8:11 AM ET 3/25/2025
Symbol Last Price Change
MRK 91.43down -0.88 (-0.9533%)
LLY 864.38down -0.52 (-0.0601%)
ULIHF 2.1down -0.25 (-10.638298%)
QUOTES AS OF 10:37:00 AM ET 03/25/2025
By Sriparna Roy
March 25 (Reuters) - Merck(MRK) has signed a licensing agreement for a heart disease drug with Jiangsu Hengrui Pharmaceuticals worth up to $2 billion, the latest in a series of deals U.S. drugmakers have recently signed with China-based firms.
Large drugmakers including Merck(MRK) and Eli Lilly(LLY) have turned to Chinese biotechs for deals that give them access to new drugs for a cheaper investment, analysts have said.
Most recently, Danish drugmaker Novo Nordisk bought global rights to China-based United Laboratories International's(ULIHF) weight-loss drug candidate in a deal worth up to $2 billion.
Merck (MRK) last year signed a licensing deal worth up to $2 billion for Chinese biotech Hansoh Pharma's experimental oral drug to treat obesity. It also bought the rights to an early-stage cancer drug from China's LaNova in an up to $3.3 billion deal.
China continues to be an interesting source of recently struck licensing deals, as more innovations at low costs are coming out of the region, said Kevin Gade, chief operating officer at Bahl & Gaynor, which owns Merck(MRK) shares.
Under the latest deal, announced on Tuesday, Merck(MRK) will get exclusive rights to develop, manufacture and sell Jiangsu Hengrui Pharmaceuticals' experimental oral heart disease drug, HRS-5346, worldwide, except in the Greater China region.
The drug, currently being studied in a mid-stage trial in China, belongs to a class of drugs which prevent formation of cholesterol, fats and proteins in the blood, which can limit the blood flow to vital organs resulting in heart attack, stroke and other cardiovascular diseases.
Hengrui Pharma will receive an upfront payment of $200 million and will be eligible for up to $1.77 billion if it meets certain development, regulatory and commercial milestones, as well as royalties on net sales of HRS-5346, if approved.
The deal is expected to close in the second quarter of 2025. (Reporting by Sriparna Roy in Bengaluru; Editing by Shounak Dasgupta and Shinjini Ganguli)