Bruker Introduces New Consumable MALDI BiotargetTM for the MALDI BiotyperTM Workflow Using Proteomic Microbial Identification
May 07 2011 - 7:00AM
Business Wire
At the 21st Annual Meeting of the European Society of Clinical
Microbiology and Infectious Diseases (www.congrex.ch/ECCMID2011),
Bruker introduces single-use MALDI BiotargetTM sample plates for
the mass spectrometry-based MALDI Biotyper workflow for microbial
identification of a wide range of microbial species by means of
specific proteomic fingerprints.
Due to its very fast result generation and superior analytical
performance, in recent years MALDI Biotyper-based molecular
identification has increasingly replaced classical biochemical
identification in clinical microbiology laboratories. The MALDI
Biotyper allows for microbial identification from pure cultures
within a few minutes. It enables a broad and unbiased
identification of more than 2,000 species of gram-negative and
gram-positive bacteria, as well as yeasts. Currently, more than 250
MALDI Biotyper systems have been installed, mostly in clinical
routine laboratories.
The MALDI Biotargets are a further addition to Bruker´s product
range for fast and cost-effective microbial identification. They
complement Bruker´s reusable steel target plates, and can, for
example, be used in laboratory networks that have a central core
facility equipped with a Bruker MALDI-TOF mass spectrometer. In
this use case, the samples can be prepared in satellite
microbiology laboratories and can be sent to the central core
laboratory for species analysis. The results can then be reviewed
via a local MALDI Biotyper software client for the final approval
of the identification by the microbiologist.
Conveniently, the MALDI Biotargets make target cleaning
procedures unnecessary, and they reduce the need for chemical
handling in laboratories. Via their barcode-label, the MALDI
Biotargets enable sample tracking of the microbial isolates. The
MALDI Biotargets are suitable for the preparation of up to 48
microbial isolates, and MALDI Biotargets are currently for
research-use-only.
An additional, proprietary reusable steel BigAnchorChipTM target
plate is the best choice for workflows coming from liquid phase,
like in the rapid detection of salmonella after pre-enrichment from
stool samples.
Dr. Ulrich Weller of Laboratory Boogen in Cologne, Germany,
stated: “Our laboratory has done most of our microbial routine
identification work with the MALDI Biotyper in the last few years.
Now we have extensively studied and validated the new consumable
MALDI Biotargets in comparison to Bruker´s reusable steel targets.
The MALDI Biotargets have shown the same excellent performance, and
make handling even more convenient. Moreover, they allow us to send
prepared samples for measurements in partner laboratories.”
Dr. Wolfgang Pusch, Vice President for Clinical Research
Solutions & IVD at Bruker Daltonics, added: “We are very
pleased to introduce the MALDI Biotargets for our customers in
microbiology to ensure high quality sample preparation to achieve
the best results for new workflows in microbiology. Our reusable
steel targets are the basic sample preparation plates for standard
workflows. The new MALDI Biotargets now allow for a further
reduction in workload and chemical handling by our customers.”
About the Bruker MALDI Biotyper
Bruker’s proprietary MALDI Biotyper solution enables molecular
identification, taxonomical classification or dereplication of
microorganisms like bacteria, yeasts and fungi. Classification and
identification of microorganisms is achieved reliably and quickly
using proteomic fingerprinting by high-throughput MALDI-TOF mass
spectrometry. Applications include clinical routine microbial
identification, environmental and pharmaceutical analysis,
taxonomical research, food and consumer product processing and
quality control, as well as marine microbiology. Bruker’s robust
MALDI Biotyper method requires minimal sample preparation efforts
and offers low consumables cost per sample. The MALDI Biotyper is
available in a research-use-only version, as well as in an IVD-CE
version according to EU directive EC/98/79 in certain European
countries. For more information, please visit
www.maldibiotyper.com.
For more information about Bruker Corporation (NASDAQ: BRKR),
please visit www.bruker.com.
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