Codex DNA Expands Application of Proprietary Error Correction Technology
October 04 2022 - 9:00AM
Codex DNA, Inc. (NASDAQ: DNAY), a pioneer in automated benchtop
synthetic biology systems, today announced commercial release of
BioXp® Error-corrected Libraries kits that enable researchers to
automate synthesis of DNA variant libraries on the award-winning
BioXp® automated synthetic biology workstation.
“This addition to the BioXp® solutions demonstrates a new and
expanded application of Codex DNA’s proprietary 2-step error
correction technology. We believe the ability to automate synthesis
of DNA variant libraries on the BioXp® system of up to 64 million
variants per well with 2-fold greater fidelity than previously will
enable scientists in applications such as antibody therapeutics,
enzyme engineering, and both gene and cell-based therapies
including precision medicine to optimize their workflows and
engineer specificity, binding, and activity of mRNA and proteins
with greater speed and accuracy,” said Todd R. Nelson, PhD, CEO of
Codex DNA.
The BioXp® system builds scanning, site-saturation and
combinatorial DNA libraries of high-fidelity customer specific
sequence variants, overnight with the push of a button.
Error-corrected libraries are generated starting with Codex DNA’s
gene synthesis, assembly, proprietary error correction technology
and amplification to yield DNA libraries of purified sequence
variants that are ready to be utilized in downstream research
applications such as cloning, screening or selection. This solution
enables researchers to build DNA libraries of up to 64 million
variants per well with 2-fold greater fidelity than non-error
corrected libraries without compromising on expected sequence
diversity of amino acids.
“By providing a solution that enables synthesis of
error-corrected libraries overnight, independent of the sequence
complexity, we empower researchers to expand and accelerate their
screening and discovery workflows and make faster strides in
cutting-edge discovery applications,” added Todd R. Nelson.
About Codex DNACodex DNA is empowering
scientists with the ability to create novel, synthetic
biology-enabled solutions for many of humanity’s greatest
challenges. As inventors of the industry-standard Gibson Assembly®
method and the first commercial automated benchtop DNA and mRNA
synthesis system, Codex DNA is enabling rapid, accurate, and
reproducible writing of DNA and mRNA for numerous downstream
markets. The award-winning BioXp® system consolidates, automates,
and optimizes the entire synthesis, cloning, and amplification
workflow. As a result, it delivers virtually error-free synthesis
of DNA and RNA at scale within days and hours instead of weeks or
months. Scientists around the world are using the technology in
their own laboratories to accelerate the design-build-test paradigm
for novel, high-value products for precision medicine, biologics
drug discovery, vaccine and therapeutic development, genome
editing, and cell and gene therapy. Codex DNA is a public company
based in San Diego. For more information,
visit codexdna.com.
Codex DNA, the Codex DNA logo, Gibson Assembly, BioXp, and
RapidAMP are trademarks of Codex DNA Inc.
Forward-Looking StatementsThis press release contains
“forward-looking statements” within the meaning of the Private
Securities Litigation Reform Act of 1995, as amended. Such
forward-looking statements are based on Codex DNA’s beliefs and
assumptions and on information currently available to it on the
date of this press release. Forward-looking statements may involve
known and unknown risks, uncertainties and other factors that may
cause Codex DNA’s actual results, performance, or achievements to
be materially different from those expressed or implied by the
forward-looking statements. These and other risks are described
more fully in Codex DNA’s filings with the Securities and Exchange
Commission (“SEC”) and other documents that Codex DNA subsequently
files with the SEC from time to time. Except to the extent required
by law, Codex DNA undertakes no obligation to update such
statements to reflect events that occur or circumstances that exist
after the date on which they were made.
Media Contact:
Charlie Schmidt
Sr. Director of Marketing
charlie@codexdna.com
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