Study Suggests Non-invasive Vagus Nerve Stimulation (nVNS) is effective in accelerating United States Air Force Pilot Training
September 10 2024 - 8:00AM
electroCore, Inc. (Nasdaq: ECOR), a commercial-stage
bioelectronic medicine and wellness company, today announced that
the Air Force Research Laboratories (AFRL) presented new results
supporting the ability of electroCore’s TAC-STIM (nVNS) to
accelerate pilot training. The presentation titled “Accelerating
Sensorimotor Learning in A Flight Training Simulation Using
Transcutaneous Vagus Nerve Stimulation” was presented on Tuesday,
August 26th at the 2024 Medical Health System Research Symposium in
Orlando, FL. by Dr. Justin Estepp of the Human Effectiveness
Directorate of the United States Air Force Research Laboratories
(AFRL). The presentation was based on a study conducted at AFRL’s
facilities at Wright-Patterson Air Force Base in Dayton, Ohio. The
study was funded by the Department of the Air Force through AFRL.
The study recruited 28 participants from the 711th Human
Performance Squadron (nVNS = 14 & Sham = 14). Each subject was
assessed on day 0 to establish a baseline. On days 1-4, two
2-minute nVNS stimulation treatments were self-administered by the
subject, before and in the middle of daily training. Each
participant completed 12 glideslope trials on days 1-4; each
simulator trial lasted approximately 2.5 minutes. Performance was
measured throughout each trial through the tracking of sensorimotor
performance. The study showed a significant positive effect
(p<0.05) of nVNS over sham on day one (37% after trial one,
increasing to 51% after trial 12). Based on a Bayesian modeling
approach, there was a 99% probability that active nVNS was superior
to sham on trial 12, suggesting that the learning rate was higher
in the active nVNS group. Additional physiological and mechanistic
data collected in the study are currently being evaluated.
“We congratulate the team at AFRL for the cutting-edge
research presented in this study,” commented Dan Goldberger,
Chief Executive Officer of electroCore. “This is the second study
in the past three months to show that TAC-STIM provided a clear
improvement in the ability of America’s warfighter to learn a
critical skill. We look forward to the additional data from this
and other on-going studies designed to identify use cases for
TAC-STIM across different branches of our Armed Forces.”
About The Air Force Research Laboratory
(AFRL)
The Air Force Research Laboratory is the primary scientific
research and development center for the Department of the Air
Force. AFRL plays an integral role in leading the discovery,
development, and integration of affordable warfighting technologies
for our air, space, and cyberspace force. With a workforce of more
than 11,500 across nine technology areas and 40 other operations
across the globe, AFRL provides a diverse portfolio of science and
technology ranging from fundamental to advanced research and
technology development. For more information, visit:
www.afresearchlab.com.
About electroCore, Inc.electroCore, Inc. is a
commercial stage bioelectronic medicine and wellness company
dedicated to improving health through its non-invasive vagus nerve
stimulation (“nVNS”) technology platform. Our focus is the
commercialization of medical devices for the management and
treatment of certain medical conditions and consumer product
offerings utilizing nVNS to promote general wellbeing and human
performance in the United States and select overseas markets.
For more information, visit www.electrocore.com.
About TAC-STIM Proudly made in the USA,
TAC-STIM™ is a non-invasive vagus nerve stimulator (nVNS) that
utilizes the company’s patented technology to stimulate the vagus
nerve. This portable device is designed to work quickly, and
enhances human performance by improving memory retention,
attention, and mood, accelerating training, and decreasing fatigue.
TAC-STIM is a low-risk general wellness product and is not intended
to treat or diagnose any medical condition or disease.
For more information, visit www.tac-stim.com.
Forward-Looking StatementsThis press release
may contain forward-looking statements within the meaning of the
Private Securities Litigation Reform Act of 1995. Such
forward-looking statements include, but are not limited to,
statements regarding the implications of the results from the AFRL
study, anticipated results and timing of clinical trials being
conducted with TAC-STIM non-invasive vagus nerve stimulation
(nVNS), electroCore's business prospects, its sales and marketing
and product development plans, future cash flow projections,
anticipated costs, its product portfolio or potential markets for
its technologies, the availability and impact of payor coverage,
the potential of nVNS generally in particular to accelerate
training, and other statements that are not historical in nature,
particularly those using terminology such as "anticipates,"
"expects," "believes," "intends," other words of similar meaning,
derivations of such words and the use of future dates. Actual
results could differ from those projected in any forward-looking
statements due to numerous factors. Such factors include, among
others, the ability to obtain additional financing necessary to
continue electroCore's business, sales and marketing and product
development plans, the uncertainties inherent in the development of
new products or technologies, the ability to successfully
commercialize nVNS products, competition in the industry in which
electroCore operates and general market conditions. The results of
earlier preclinical studies and clinical trials may not be
predictive of results of future preclinical studies, clinical
trials, or commercial success. All forward-looking statements are
made as of the date of this press release, and electroCore
undertakes no obligation to update forward-looking statements or to
update the reasons why actual results could differ from those
projected in the forward-looking statements, except as required by
law. Investors should refer to all information set forth in this
document and should also refer to the disclosure of risk factors
set forth in the reports and other documents electroCore files with
the SEC, available at www.sec.gov.Contact:ECOR
Investor Relations(973) 302-9253investors@electrocore.com
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