Gene Logic Enters Into Agreement with Lundbeck to Discover New Development Paths for Clinical Drug Candidates
June 28 2007 - 6:00AM
Business Wire
Gene Logic Inc. (NASDAQ:GLGC) announced today that it has entered
into a drug repositioning and development agreement with H.
Lundbeck A/S to seek alternative development paths for certain
Lundbeck drug candidates. These drug candidates were discontinued
or de-prioritized in clinical trials for reasons other than safety.
The drug repositioning agreement provides for milestones and
royalties similar to those paid for development-stage in-licensing
deals, discounted to account for Lundbeck�s contribution as the
originator of the compound. The agreement also provides Gene Logic
the option to receive an exclusive license to any of these drug
candidates for which Gene Logic identifies a potential new use and
that Lundbeck chooses not to pursue, in which case Lundbeck would
receive success-based milestone and royalty payments. Gene Logic�s
Drug Repositioning Program seeks to find alternative development
paths for drug candidates with good safety records that have been
de-prioritized or discontinued in clinical trials. The program
offers pharmaceutical partners a novel approach to bolster their
pipelines with high-quality drug candidates that originated from
their own R&D efforts. Applying a diverse set of drug discovery
technologies in parallel, Gene Logic�s Drug Repositioning Program
evaluates drug candidates for potential utility across a wide
spectrum of disease indications. Charles L. Dimmler, III, Gene
Logic CEO commented, �Lundbeck has an outstanding reputation as a
developer of therapeutics for central nervous system disorders. We
are pleased to be partnering with an innovative organization such
as Lundbeck. With six current pharmaceutical company drug
repositioning partnerships, our approach is establishing Gene Logic
as the industry�s drug repositioning leader.� In a separate
agreement unrelated to its drug repositioning partnerships, Gene
Logic announced that it expects to realize approximately $2.5
million in fees from Lundbeck for a license to certain technology
rights controlled by Gene Logic. The revenue will be recognized
over the coming year. Gene Logic Overview Gene Logic is
transforming into a biopharmaceutical development company through
partnerships with pharmaceutical companies. Our partners provide
Gene Logic with access to their drug candidates that have been
assessed as safe in human clinical trials but discontinued for
other reasons. Gene Logic applies its drug indication platform to
find new therapeutic uses for the drug candidates. Gene Logic
expects to receive milestone payments and royalties on drug
candidates that our partners choose to develop based on the
indications we find or, if the partner elects not to pursue such
new indications, Gene Logic may receive ownership and development
rights. Gene Logic has also developed proprietary genomics
databases and services to enable customers worldwide to discover
and prioritize drug targets, identify biomarkers, predict toxicity
and understand mechanisms of toxicity, and obtain insights into the
efficacy of specific compounds. Founded in 1994, Gene Logic is
headquartered in Gaithersburg, Maryland, with additional research
and development facilities in Cambridge, Massachusetts. The Company
currently has about 150 employees worldwide. For more information,
visit www.genelogic.com or call toll-free � 1/800/GENELOGIC. Safe
Harbor Statement This press release contains �forward-looking
statements,� as such term is used in the Securities Exchange Act of
1934, as amended. Such forward-looking statements include the
Company�s ability to identify strategies for making its businesses
successful and the impact of such strategies on our business and
financial performance and on shareholder value. Forward-looking
statements typically include the words �expect,� �anticipate,�
�believe,� �estimate,� �intend,� �may,� �will,� and similar
expressions as they relate to Gene Logic or its management.
Forward-looking statements are based on our current expectations
and assumptions, which are subject to risks and uncertainties. They
are not guarantees of our future performance or results. Our actual
performance and results could differ materially from what we
project in forward-looking statements for a variety of reasons and
circumstances, including particularly such risks and uncertainties
that may affect the Company�s operations, financial condition and
financial results and that are discussed in detail in the Company�s
Annual Report on Form 10-K and our other subsequent filings with
the Securities and Exchange Commission. They include, but are not
limited to: whether we will be able to identify and successfully
implement strategies, on favorable terms or at all, for improving
the performance and value of our businesses and improving the value
of our Genomics business and whether repositioned compounds are
successfully returned to our customers� pipelines and generate
sales, and resulting milestones and royalties for the Company or
whether we acquire repositioned compounds on acceptable terms and
are able to derive revenue from these compounds through licensing
or otherwise, whether we can enter into agreements to develop
sufficient compounds to fulfill our plans for the Drug
Repositioning Division, and improving the value of our businesses
to shareholders; whether there will be remaining price adjustments
or liabilities associated with the sale of the Pre-Clinical
Division, whether we will be able successfully to manage our
existing cash adequately and whether we will have access to
financing on sufficiently favorable terms to maintain our
businesses and effect our strategies, including development of
repositioned compounds; whether we will be able to recruit and
retain qualified personnel, particularly in light of our
restructuring efforts; potential negative effects on our operations
and financial results from workforce reductions, other
restructuring activities, and the evaluation of strategic options;
the potential loss of significant customers; the possibility of
further write-down of the value of certain intangible assets of the
Company, including goodwill associated with the Genomics Division;
and the possibility of delisting from NASDAQ Global Markets, which
could have an adverse effect on the value of our stock. Gene Logic
undertakes no obligation to update or revise any forward-looking
statements, whether as a result of new information, future events
or otherwise.
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