Apollomics Inc. (“Apollomics” or the “Company”), a clinical-stage
biopharmaceutical company developing multiple oncology drug
candidates to address difficult-to-treat and treatment-resistant
cancers, today announced the completion of its business combination
(the “Business Combination”) with Maxpro Capital Acquisition Corp.
(“Maxpro”, Nasdaq: JMAC). Apollomics’ Class A ordinary shares and
public warrants are expected to commence trading today, March 30,
2023, on the Nasdaq Capital Market (Nasdaq) under the symbols
"APLM" and “APLMW,” respectively. The Business Combination, which
was approved by Maxpro’s shareholders on March 20, 2023, along with
a $23.65 million private investment in public equity (PIPE)
financing raised in connection with the Business Combination,
provides access to capital that is expected to enable the Company
to advance its pipeline of drug candidates.
Apollomics’ mission is to improve treatment options for patients
diagnosed with difficult-to-treat, high mortality cancers.
Apollomics’ pipeline includes nine novel oncology drug candidates,
six of which are currently in clinical stage of development. By
using targeted therapy, immuno-oncology agents, and other
innovative approaches, Apollomics’ novel drug candidates have the
potential to address a range of cancers, including lung cancer,
brain cancer, acute myeloid leukemia, and other solid tumors.
Apollomics expects results from its global Phase 2 multi-cohort
clinical trial of vebreltinib (APL-101), a highly specific cMet
inhibitor, in non-small cell lung cancer and other solid tumors
with cMet dysregulation, this year, which the Company believes may
support its first new drug application with the U.S. Food and Drug
Administration (FDA) while generating clinical data on other
indications. Apollomics is also developing uproleselan (APL-106),
an E-selectin inhibitor, in China as an adjunct to chemotherapy to
enhance its anti-cancer effects for adult patients with relapsed or
refractory acute myeloid leukemia. The FDA granted Breakthrough
Therapy Designation to GlycoMimetics, Apollomics’ collaboration
partner in the United States, for uproleselan, and the China
National Medical Products Administration (NMPA) designated it as a
breakthrough therapy in China. The Company expects to complete
patient recruitment of its Phase 3 study for uproleselan (APL-106)
in China this year.
“Becoming a public company represents a major milestone in our
journey to provide solutions for patients with difficult-to-treat
cancers worldwide,” said Dr. Guo-Liang Yu, Ph.D., Chairman and
Chief Executive Officer of Apollomics. “The funds now available to
us are expected to facilitate development of our oncology pipeline
and further our mission to provide patients with effective
therapies and hope.”
Moses Chen, Chief Executive Officer of Maxpro, said, “We are
thrilled to have completed the Business Combination with
Apollomics. We’re confident that the Company’s cutting-edge
drug candidates will deliver value to investors while advancing the
Company’s ability to provide treatment options for patients
diagnosed with difficult-to-treat, high mortality
cancers.”
Apollomics will continue to be led by Dr. Yu, a serial
entrepreneur and pharmaceutical researcher with more than 300
patents, as its Chief Executive Officer and Chairman of the Board
of Directors.
The Apollomics executive leadership team will also consist
of:
- Dr. Sanjeev Redkar, Ph.D., MBA, Apollomics’ Co-Founder, who
will continue to serve as President and will serve as a
Director;
- Dr. Jane Wang, Ph.D., who will continue to serve as Chief
Scientific Officer; and
- Dr. Peony Yu, MD, who will continue to serve as Chief Medical
Officer.
In addition to Dr. Yu and Dr. Redkar, Apollomics’ Board of
Directors will also consist of: Dr. Jonathan Wang, Ph.D., MBA; Dr.
Kenneth C. Carter, Ph.D.; Dr. Hong-Jung (Moses) Chen, Ph.D.; Wendy
Hayes, MBA; and Glenn S. Vraniak, MBA.
Advisors
EF Hutton, division of Benchmark Investments, LLC served as
capital markets advisor and exclusive placement agent to Maxpro.
Nelson Mullins Riley & Scarborough LLP served as legal advisor
to Maxpro. White & Case LLP served as legal advisor to
Apollomics.
About Apollomics Inc.
Apollomics Inc. is an innovative clinical-stage
biopharmaceutical company focused on the discovery and development
of oncology therapies with the potential to be combined with other
treatment options to harness the immune system and target specific
molecular pathways to inhibit cancer. Apollomics currently has a
pipeline of nine drug candidates across multiple programs, six of
which are currently in the clinical stage of development.
Apollomics’ lead programs include investigating its core product,
vebreltinib (APL-101), a potent, selective c-Met inhibitor for the
treatment of non-small cell lung cancer and other advanced tumors
with c-Met alterations, which is currently in a Phase 2 multicohort
clinical trial in the United States, and developing an anti-cancer
enhancer drug candidate, uproleselan (APL-106), a specific
E-Selectin antagonist that has the potential to be used
adjunctively with standard chemotherapy to treat acute myeloid
leukemia and other hematologic cancers, which is currently in Phase
1 and Phase 3 clinical trials in China.
Cautionary Statement Regarding Forward-Looking
Statements
This press release includes statements that constitute
“forward-looking statements” within the meaning of the federal
securities laws, including Section 27A of the Securities Act of
1933, as amended (the “Securities Act”), and Section 21E of the
Securities Exchange Act of 1934, as amended (the “Exchange Act”).
All statements, other than statements of present or historical fact
included in this press release, regarding the Company’s future
financial performance, as well as the Company’s strategy, future
operations, revenue guidance, projected costs, prospects, plans and
objectives of management are forward-looking statements. When used
in this press release, the words “could,” “should,” “will,” “may,”
“believe,” “anticipate,” “intend,” “estimate,” “expect,” “project,”
the negative of such terms and other similar expressions are
intended to identify forward-looking statements, although not all
forward-looking statements contain such identifying words. These
forward-looking statements are based on management’s current
expectations and assumptions about future events and are based on
currently available information as to the outcome and timing of
future events. Apollomics cautions you that these forward-looking
statements are subject to numerous risks and uncertainties, most of
which are difficult to predict and many of which are beyond the
control of Apollomics. In addition, Apollomics cautions you that
the forward-looking statements contained in this press release are
subject to unknown risks, uncertainties and other factors,
including: (i) the impact of any current or new government
regulations in the United States and China affecting Apollomics’
operations and the continued listing of Apollomics’ securities;
(ii) the inability to achieve successful clinical results or to
obtain licensing of third-party intellectual property rights for
future discovery and development of Apollomics’ oncology projects;
(iii) the failure to commercialize product candidates and achieve
market acceptance of such product candidates; (iv) the failure to
protect Apollomics’ intellectual property; (v) breaches in data
security; (vi) risks related to the ongoing COVID-19 pandemic and
response; (vii) the risk that Apollomics may not be able to develop
and maintain effective internal controls; (viii) unfavorable
changes to the regulatory environment; and those risks and
uncertainties discussed in the Form F-4 (as amended) filed by
Apollomics, Inc. with the U.S. Securities and Exchange Commission
(“SEC”) under the heading “Risk Factors” and the other documents
filed, or to be filed, by the Company with the SEC. Other unknown
or unpredictable factors also could have material adverse effects
on the Company’s future results and/or could cause our actual
results and financial condition to differ materially from those
indicated in the forward-looking statements. Should one or more of
the risks or uncertainties described in this press release
materialize or should underlying assumptions prove incorrect,
actual results and plans could differ materially from those
expressed in any forward-looking statements. New risk factors that
may affect actual results or outcomes emerge from time to time and
it is not possible to predict all such risk factors, nor can
Apollomics assess the impact of all such risk factors on its
business, or the extent to which any factor or combination of
factors may cause actual results to differ materially from those
contained in any forward-looking statements. Forward-looking
statements are not guarantees of performance. You should not put
undue reliance on these statements, which speak only as of the date
hereof. Additional information concerning these and other factors
that may impact the operations and projections discussed herein can
be found in the reports that Apollomics has filed and will file
from time to time with the SEC. These SEC filings are available
publicly on the SEC’s website at www.sec.gov. Apollomics undertakes
no obligation to update publicly any of these forward-looking
statements to reflect actual results, new information or future
events, changes in assumptions or changes in other factors
affecting forward-looking statements, except to the extent required
by applicable laws. If Apollomics updates one or more
forward-looking statements, no inference should be drawn that
Apollomics will make additional updates with respect to those or
other forward-looking statements.
CONTACTS
Investor RelationsPeter VozzoICR
WestwickePeter.Vozzo@westwicke.com443-213-0505
Media RelationsSean LeousICR
WestwickeSean.Leous@westwicke.com646-866-4012
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