CARLSBAD, Calif., Feb. 23,
2023 /PRNewswire/ -- Natural Alternatives
International, Inc. ("NAI") (Nasdaq: NAII), an international leader
in custom contract nutritional supplement manufacturing for over
four decades, today announced that new research on the cognitive
benefits of SR CarnoSyn® beta-alanine tablets, a
patented sustained release delivery system owned by NAI, has been
published in Nutrients.
Natural Alternatives International
announces new research on the cognitive benefits of SR CarnoSyn®
beta-alanine tablets
The benefits of CarnoSyn® Brands' beta-alanine
supplementation on functional performance in older adults has been
reported in several prior clinical studies. These human studies
have demonstrated that supplementing with CarnoSyn®
beta-alanine can delay fatigue, increase strength, and improve
functional performance. Various clinical studies concluded that
CarnoSyn® beta-alanine supplementation is associated
with improved executive function and that the anti-inflammatory and
antioxidant effects of increased tissue carnosine levels supports
improved health in older adults.
This new clinical study provided the biggest scale of
participants with precise experimental designs, showing SR
CarnoSyn® beta-alanine supplementation benefits
cognitive function in sedentary older adults. This clinical study
is also the first conducted with a 600 milligram SR
CarnoSyn® beta-alanine tablet providing 2.4 grams of
daily supplementation. The study results indicated improved
cognitive function in older adults whose cognitive function at
baseline was at or below normal. In addition, results indicated
significant depression score reductions using the Geriatric
Depression Scale (GDS).
The study included one hundred older adults between the ages of
60-80 who volunteered to participate in this double-blind,
randomized controlled study. Any participant who had underlying
neurological conditions was not eligible to enroll in the study.
All interviews were conducted by a licensed physician. Participants
were not permitted to use any additional nutritional supplements
for at least six weeks prior to the study.
Before taking their first supplement, participants completed
several tests consisting of written questionnaires to assess
cognitive function and mood, and a computer-based exam to measure
cognitive and executive function. In addition, a series of physical
function tests were performed.
Testing occurred prior to supplementation, at the midpoint, and
at week ten. Participants were instructed to consume two 600 mg
tablets twice per day for the duration of the ten-week study. The
SR CarnoSyn® beta-alanine supplement and the placebo
were identical in appearance.
Cognitive and mood measures consisted of cognitive function
assessments, including the Montreal Cognitive Assessment (MoCA),
the Stroop pattern recognition test, and the Profile of Mood States
(POMS). In addition, participants were also asked to complete the
Geriatric Depression Scale (GDS) and the Geriatric Anxiety Scale
(GAS).
"CarnoSyn® Brands has been devoted to
science-based ingredients and products for over 15 years," said
Aaron Starr, Vice President,
CarnoSyn® Brands. "We were very excited to sponsor this
clinical study with such a prestigious institution and research
team. This was a well-crafted and executed clinical study,
especially considering the difficulties of recruiting participants
and conducting this study during the pandemic. The positive study
results help bolster our existing and extensive
CarnoSyn® research and provides additional
scientific evidence of the benefits of
CarnoSyn® beta-alanine to help further educate our
customers and consumers."
SR CarnoSyn® has six research studies showing brain
health and mood improvement, with numerous benefits for users:
- Improves executive functioning, mental clarity and enhances
cognitive process.
- Reduces mental fatigue.
- Supports brain health, cognitive function, and memory.
- Studies show improved attention and task focus in adults.
- Helps boost mental clarity, concentration, and alertness.
- Promotes a healthy response to everyday stress.
- Fosters a more balanced mood and supports a sense of calm.
About CarnoSyn® Brands:
CarnoSyn® Brands feature two clinically studied,
patented ingredients available exclusively from Natural
Alternatives International, Inc.: CarnoSyn® instant
release beta-alanine powder and SR CarnoSyn® sustained
release beta-alanine tablets. In 2019, CarnoSyn®
beta-alanine successfully obtained NDI status from the FDA and
received Self-Affirmed GRAS (Generally Recognized as Safe) status.
SR CarnoSyn®, an advanced delivery form of
CarnoSyn®, received GRAS affirmation in 2017. The GRAS
affirmation allows NAI to broaden their product offerings within
the food and beverage industries, including medical and other
fortified food products.
About NAI:
NAI, headquartered in Carlsbad, California, is a leading formulator,
manufacturer and marketer of nutritional supplements and provides
strategic partnering services to its customers. NAI's comprehensive
partnership approach offers a wide range of innovative nutritional
products and services to clients including scientific research,
proprietary ingredients, customer-specific nutritional product
formulation, product testing and evaluation, marketing management
and support, packaging and delivery system design, regulatory
review, and international product registration assistance. For more
information about NAI, please visit www.nai-online.com.
For more information, visit: www.srcarnosyn.com
Contact:
Renee
Michaelson
Director of Global Marketing
NAI/CarnoSyn® Brands
(760) 736-7700
info@nai-online.com
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SOURCE Natural Alternatives International, Inc.