UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

NOTICE OF EFFECTIVENESS

Effective Date: December 13, 2017
Accession Number: 0001193125-17-365726
Submission Type: POS AM
CIK: 0001274644
Company Name: Ocera Therapeutics, Inc.
File Number: 333-192698
Ocera Therapeutics, Inc. (NASDAQ:OCRX)
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