ONVO Organovo Holdings Inc

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d)

OF THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of Earliest Event Reported): August 21, 2013

ORGANOVO HOLDINGS, INC.

(Exact name of registrant as specified in its charter)

(858) 550-9994

(Registrant’s telephone number, including area code)

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

In conjunction with the 2013 Annual Meeting of Stockholders (the “Annual Meeting”) of Organovo Holdings, Inc. (the “Company”) held on August 21, 2013, the Company’s stockholders approved an amendment to the 2012 Equity Incentive Plan to increase the number of shares of common stock issuable under the Plan by 5,000,000 shares (the “Amendment”). A copy of the Amendment is filed as Exhibit 10.1 to this report and is incorporated herein by reference.

Item 5.07 Submission of Matters to a Vote of Security Holders.

The Company held its Annual Meeting on August 21, 2013. Of the 64,951,014 shares of the Company’s common stock outstanding as of the record date, 42,843,440 shares were represented at the Annual Meeting either in person or by proxy.

A description of each matter voted upon at the Annual Meeting is described in detail in the Company’s definitive proxy statement filed with the Securities and Exchange Commission on July 12, 2013. The number of votes cast for and against (or withheld) and the number of abstentions and broker non-votes with respect to each matter voted upon are set forth below.

(1) Election of Directors. The Company’s stockholders elected Tamar Howson and Richard Heyman, Ph.D. as Class II directors to hold office until the 2016 Annual Meeting of Stockholders and until their respective successors are elected and qualified as follows:

(2) Ratification of Auditors. The Company’s stockholders ratified the appointment of Mayer Hoffman McCann P.C. as the Company’s independent registered public accounting firm for the fiscal year ending March 31, 2014 as follows:

(3) Executive Compensation. The Company’s stockholders, on a non-binding, advisory basis, approved the compensation of the Company’s named executive officers as disclosed in the definitive proxy statement as follows:

(4) Frequency of Executive Compensation Vote. The Company’s stockholders, on a non-binding, advisory basis, selected three (3) years as the frequency of the advisory vote on the compensation of the Company’s named executive officers as follows:

(5) Plan Amendment. The Company’s stockholders approved an amendment to the 2012 Equity Incentive Plan (the “Plan”) to increase the number of shares of common stock issuable under the Plan by 5,000,000 shares as follows:

No other items were presented for stockholder approval at the Annual Meeting.

Following the Annual Meeting, the Company’s Board of Directors and Compensation Committee met to discuss the frequency of the non-binding, advisory vote on the compensation of the Company’s named executive officers. The Board of Directors and Compensation Committee considered the voting results from the Annual Meeting. They also considered the reasons for recommending an annual frequency to the Company’s stockholders as described in the definitive proxy statement for the Annual Meeting. Following this analysis and discussion, the Company’s Board of Directors, with the recommendation of the Compensation Committee, determined that it was in the best interests of the Company and its stockholders to hold an annual non-binding, advisory vote on the compensation of the Company’s named executive officers.

Item 9.01 Financial Statements and Exhibits

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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