FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

FEDERICI WILLIAM J 		2. Issuer Name and Ticker or Trading Symbol

NUPATHE INC. [ PATH ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

C/O NUPATHE INC.,, 7 GREAT VALLEY PARKWAY, SUITE 300 		3. Date of Earliest Transaction (MM/DD/YYYY)

2/21/2014
(Street)

MALVERN, PA 19355
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   (1) 2/21/2014     D    13500   D $6.80   (2) 0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock option (right to buy)   $9.00   2/21/2014     D         7486      (3) 1/5/2021   Common Stock   7486   $0.00   (4) 0   D    
Stock option (right to buy)   $7.75   2/21/2014     D         6014      (3) 3/3/2021   Common Stock   6014   $0.00   (4) 0   D    
Stock option (right to buy)   $7.66   2/21/2014     D         6750      (3) 6/8/2021   Common Stock   6750   $0.00   (4) 0   D    
Stock option (right to buy)   $3.70   2/21/2014     D         2802      (3) 3/31/2022   Common Stock   2802   $3.10   (4) 0   D    
Stock option (right to buy)   $3.37   2/21/2014     D         6750      (3) 6/7/2022   Common Stock   6750   $3.43   (4) 0   D    
Stock option (right to buy)   $4.03   2/21/2014     D         2436      (3) 6/30/2022   Common Stock   2436   $2.77   (4) 0   D    
Stock option (right to buy)   $3.56   2/21/2014     D         2791      (3) 9/30/2022   Common Stock   2791   $3.24   (4) 0   D    
Stock option (right to buy)   $3.38   2/21/2014     D         2916      (3) 12/31/2022   Common Stock   2916   $3.42   (4) 0   D    
Stock option (right to buy)   $3.45   2/21/2014     D         2157      (3) 3/31/2023   Common Stock   2157   $3.35   (4) 0   D    
Stock option (right to buy)   $2.99   2/21/2014     D         13500      (3) 6/5/2023   Common Stock   13500   $3.81   (4) 0   D    
Stock option (right to buy)   $3.06   2/21/2014     D         3063      (3) 6/30/2023   Common Stock   3063   $3.74   (4) 0   D    
Stock option (right to buy)   $2.41   2/21/2014     D         4795      (3) 9/30/2023   Common Stock   4795   $4.39   (4) 0   D    
Stock option (right to buy)   $3.27   2/21/2014     D         3538      (3) 12/31/2023   Common Stock   3538   $3.53   (4) 0   D    

Explanation of Responses:
( 1)  Includes all restricted stock units that became fully vested upon the consummation of the merger (the "Merger") contemplated by the Agreement and Plan of Merger, dated January 17, 2014, among the issuer, Teva Pharmaceutical Industries Ltd. and Train Merger Sub, Inc.(the "Merger Agreement").
( 2)  Disposed upon the Merger, in exchange for $3.65 per share, plus contractual rights to receive up to an additional $3.15 in contingent cash consideration payments per share.
( 3)  Pursuant to the Merger Agreement, all options became fully vested upon the consummation of the Merger.
( 4)  Pursuant to the Merger Agremeent, the option was converted into the right to receive, at the earliest date at which the sum of (1) the $3.65 per share cash portion of the merger consideration and (2) the amount per share in cash previously paid or to be paid at such date in connection with the Contingent Cash Consideration Agreement entered into in connection with the Merger Agreement (such sum, the "Per Share Paid Value") exceeds the per-share exercise price under the option: (x) an amount in cash equal to the number of shares of common stock subject to the option multiplied by the excess of (i) the then applicable Per Share Paid Value over (ii) the per-share exercise price under the option; and (y) the right to receive, in respect of each share of common stock subject to the option, each contingent cash consideration payment that, as of such date, has not yet become payable.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
FEDERICI WILLIAM J
C/O NUPATHE INC.,
7 GREAT VALLEY PARKWAY, SUITE 300
MALVERN, PA 19355 		X



Signatures
/s/ Michael F. Marino, attorney-in-fact 2/25/2014
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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