SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 


 

FORM 6-K

 

 

REPORT OF FOREIGN PRIVATE ISSUER

Pursuant to Rule 13a-16 or 15d-16 of

the Securities Exchange Act of 1934

 

4th July 2008

 

 

PROTHERICS PLC

(Translation of Registrant’s Name Into English)

 

 

The Heath Business & Technical Park
Runcorn, Cheshire, W47 4QF England

(Address of Principal Executive Offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

 

Form 20-F       X              Form 40-F               

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):             

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 191(b)(7):             

 

Indicate by check mark whether the registrant by furnishing the information contained in this form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

 

Yes                     No          X     

 

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82-              .

 

 

The Registrant is furnishing a copy of its announcements as reported to the Company Announcements Office of the London Stock Exchange.

 

 

 

 

 
 
Protherics PLC

Notification of Major Interest
s
 in Shares


Lon
don, UK; Brentwood, TN, US:
 
4 July 2008
 -
 Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care an
d cancer, announces 
that
 on 
3 July 
200
8
, in accordance with the Transparency Obligations Directive, 
notification 
of interest in the ordinary share capital of the Company 
was received 
from 
AXA 
I
nvestment Managers 
UK 
Limited on behalf of AXA S.A.
 and its Group C
ompanies
 ("AXA")
.  
The notification follows a 
disposal of voting rights
.  
Details 
of the
 interest 
notified 
are as follows:


1.
    
Reason for the 
notification
 
(please tick the appropriate box or boxes)
   
 



A
 disposal
 of voting rights 

X
An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to w
hich voting rights are attached



An event changing the breakdown of
 voting rights



Other (please 
s
pecify):



2
. Full name of person(s) subject to the notification obligation:
AXA 
S.A.
, 25 Avenue Matignon, 75008 Paris and its group of companies.
3
. Full name of shareholder(s) 
(if different from 2
.):


4
. Date of the transaction (and date on which the threshold is crossed or reached if different):
2
 July 2008
5
. Date on which issuer notified:
3 July 2008
6
. Threshold(s) that is/are crossed or reached:
13
%
7. Notified details:

A: Voting rights attached to shares
Class/type of shares 
if possible using the ISIN CODE
Situation previous to the Triggering transaction 
Resulting situation after the triggering transaction
Number of Shares 
Number of Voting Rights 
Number of shares
 
Number of voting rights 
% of voting rights
Direct
Direct
Indirect 
Direct
Indirect

0702920


4
4,836,830

44,836,830

9
41
,
666

9
41,666


40,
774,831

0.28
%

11.98
%

B: Financial Instruments
Resulting situation after the triggering transaction 
Type of financial instrument 
Expiration date 
Exercise/ Conversion Period/ Date
 
Number of voting rights that may be acquired if the instrument is exercised/ converted. 
% of voting rights







Total (A+B)
N
umber of voting rights
% of voting rights

41,
716,497

12.25
%

8
.
 
Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable :
Name of Company/Fund

Number of Shares
% of issued share capita
l
AXA UK Investment Co ICVC
UK
 Smaller Companies Fund
Indirect
552,143
0.16220
Sun Life Pensions Management Ltd
Direct
225,000
0.06610
Sun Life Unit Assurance Ltd
FTSE All Share Tracker
Direct
53,913
0.01584
Sun Life Pensions Management
FTSE All Share Tracker
Direct
294,874
0.08662
AXA Framlington
Indirect
425,000
0.12485
AXA Framlington
Indirect
1,851,468
0.54388
AXA Framlington
Indirect
1,909,918
0.56105
AXA Framlington
Indirect
459,865
0.13509
AXA Framlington
Indirect
639,353
0.18781
AXA Framlington
Indirect
15,438,453
4.53516
AXA Framlington
Indirect
13,753,131
4.04008
AXA Framlington
Indirect
2,000,000
0.58751
AXA Framlington
Indirect
1,500,000
0.44064
AXA Framlington
Indirect
500,000
0.14688
AXA Framlington
Indirect
220,000
0.06463
Framlington onshore private clients
Indirect
975,500
0.28656
AXA Sun Life ith Profits Passive
Direct
226,817
0.06663
AXA Sun Life With Profits Passive
Direct
141,062
0.04144
AXA Framlington
Indirect
550,000
0.16157

Total Direct
Total Indirect

941,666
40,774,831

0.27662
11.97790

TOTAL

41,716,497

12.25452

Proxy Voting:
9
. Name of the proxy holder:

1
0
. Number of voting rights proxy holder will cease to hold:

11
. Date on which proxy holder will cease to hold voting
 
rights:

12
. Additional information:





| Ends |


F
or f
urther 
i
nformation
 please contact
:

Protherics 

Nick Staples
Director of Corporate 
Affairs
+44 (0) 7919 480510  
Julie Vickers, Company Secretary 
+44 (0)
1928 518010


Financial Dynamics
 
- press enquiries

London:
 Ben Atwell, 
Lara Mott
+44 (0) 20 7831 3113 
New York
:
 John Capodanno
+1 212 850 5600

Or visi
t  
www.protherics.com

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

       

 

PROTHERICS PLC

       

Date: 4th July 2008

 

By:

 

/s/ Rolf Soderstrom


       

Rolf Soderstrom

       

Finance Director

 

 

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