SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 

 

FORM 6-K

 

 

REPORT OF FOREIGN PRIVATE ISSUER

Pursuant to Rule 13a-16 or 15d-16 of

the Securities Exchange Act of 1934

 

03 September 2008

 

 

PROTHERICS PLC

(Translation of Registrant’s Name Into English)

 

 

The Heath Business & Technical Park
Runcorn, Cheshire, W47 4QF England

(Address of Principal Executive Offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

 

Form 20-F       X              Form 40-F               

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):             

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 191(b)(7):             

 

Indicate by check mark whether the registrant by furnishing the information contained in this form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

 

Yes                     No          X     

 

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82-              .

 

 

The Registrant is furnishing a copy of its announcements as reported to the Company Announcements Office of the London Stock Exchange.

 

 

Protherics PLC

Notification of Major Interests in Shares

Lon don, UK; Brentwood, TN, US: 3 September 2008 - Protherics PLC (“Protherics” or the “Company”), the international biopharmaceutical company focused on critical care and cancer, announces that on 2 September 2008, in accordance with the Transparency Obligations Directive, a notification of interest in the ordinary share capital of the Company was received from Citigroup on behalf of Standard Life Investments Ltd. Details of the interest notified are as follows:

1.     Reason for the notification (please tick the appropriate box or boxes)

 

An acquisition of voting rights

Yes

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

 

An event changing the breakdown of voting rights

 

Other (please specify):

 

2. Full name of person(s) subject to the notification obligation:

Standard Life Investments Ltd

3. Full name of shareholder(s) (if different from 2.):

Vidacos Nominees

4. Date of the transaction (and date on which the threshold is crossed or reached if different):

28 August 2008

5. Date on which issuer notified:

2 September 2008

6. Threshold(s) that is/are crossed or reached:

crossed 3%, 4% and 5% thresholds

7. Notified details:



A: Voting rights attached to shares

Class/type of shares

if possible using the ISIN CODE

Situation previous to the Triggering transaction

Resulting situation after the triggering transaction

Number of Shares

Number of Voting Rights

Number of shares

Number of voting rights

% of voting rights

 

Direct

Indirect

Direct

Indirect

Ordinary 2P Shares
(GB0007029209)

Below 3%

Below 3%

17,953,060

5,846,047

12,107,013

1.709%

3.538%



 

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ Conversion Period/ Date

Number of voting rights that may be acquired if the instrument is exercised/ converted.

% of voting rights

         
         

Total (A+B)

N umber of voting rights

% of voting rights

17,953,060

5.247%



8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable :

Standard Life Investments Ltd

 

Proxy Voting:

9. Name of the proxy holder:

 

10. Number of voting rights proxy holder will cease to hold:

 

11. Date on which proxy holder will cease to hold voting rights:

 


12. Additional information:

 


| Ends |

F or f urther i nformation please contact :

Protherics

 

Nick Staples, Director of Corporate Affairs

+44 (0) 7919 480510

Julie Vickers, Company Secretary

+44 (0)1928 518010

   

Financial Dynamics – press enquiries

 

London: Ben Atwell, Lara Mott

+44 (0) 20 7831 3113

New York: John Capodanno

+1 212 850 5600



Or visi t www.protherics.com

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

       

 

PROTHERICS PLC

       

Date: 03 September 2008

 

By:

 

/s/ Rolf Soderstrom

       

Rolf Soderstrom

       

Finance Director

 

 

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