As filed with the Securities and Exchange Commission on June 19, 2012
Registration Statement No. 333-40524
Registration Statement No. 333-65616
Registration Statement
No. 333-101632
Registration Statement No. 333-108096
Registration Statement No. 333-117140
Registration Statement No. 333-158521
Registration Statement
No. 333-176517
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
Post-Effective
Amendment No. 1 to Form S-8 Registration Statement No. 333-40524
Post-Effective Amendment No. 1 to Form
S-8 Registration Statement No. 333-65616
Post-Effective Amendment No. 1 to Form S-8 Registration Statement
No. 333-101632
Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-108096
Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-117140
Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-158521
Post-Effective Amendment No. 1 to Form S-8 Registration Statement No. 333-176517
UNDER
THE SECURITIES ACT OF 1933
ARDEA
BIOSCIENCES, INC.
(Exact name of registrant as specified in its charter)
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Delaware
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94-3200380
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(State or other jurisdiction of
incorporation or organization)
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(I.R.S. Employer
Identification No.)
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4939 Directors Place
San Diego, CA
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92121
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(Address of Principal Executive Offices)
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(Zip Code)
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Ardea Biosciences, Inc. Amended and Restated 2004 Stock Incentive Plan
Ardea Biosciences, Inc. 2000 Employee Stock Purchase Plan
Ardea Biosciences, Inc. 2002 Non-Officer Equity Incentive Plan, as amended
Ardea Biosciences, Inc. 2000 Equity Incentive Plan, as amended
Ardea Biosciences, Inc. Amended and Restated 1995 Stock Option Plan
(Full titles of the plans)
Barry D.
Quart, Pharm.D.
Chief Executive Officer
Ardea Biosciences, Inc.
4939 Directors Place
San Diego, CA 92121
(Name and address of agent for service)
(858) 652-6500
(Telephone number, including area code, of agent for service)
Copies to:
Catherine J. Dargan
Covington & Burling LLP
1201 Pennsylvania Avenue, NW
Washington, DC 20004
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller
reporting company. See the definitions of large accelerated filer, accelerated filer and smaller reporting company in Rule 12b-2 of the Exchange Act. (Check one):
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Large accelerated filer
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¨
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Accelerated filer
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x
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Non-accelerated filer
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¨
(Do not check if a smaller reporting company)
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Smaller reporting company
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¨
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DEREGISTRATION OF SECURITIES
This Post-Effective Amendment relates to the following Registration Statements of Ardea Biosciences, Inc. (the Company) on
Form S-8 (collectively, the Registration Statements):
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1.
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Registration Statement No. 333-40524, registering an aggregate of 8,954,886 shares of common stock, par value $0.001 per share, of the Company (Common
Stock) under the Companys (a) Amended and Restated 1995 Stock Option Plan, (b) 2000 Equity Incentive Plan (the 2000 Plan) and (c) 2000 Employee Stock Purchase Plan (the ESPP), as previously filed
with the U.S. Securities and Exchange Commission (the SEC) on June 30, 2000;
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2.
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Registration Statement No. 333-65616, registering an aggregate of 1,683,910 shares of Common Stock under the 2000 Plan and the ESPP, as previously filed with the
SEC on July 23, 2001;
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3.
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Registration Statement No. 333-101632, registering an aggregate of 2,275,000 shares of Common Stock under the Companys 2002 Non-Officer Equity Incentive Plan
(the 2002 Plan) and Stock Option Agreements for Kathleen D. LaPorte and Ernest Mario, Ph.D., as previously filed with the SEC on December 4, 2002;
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4.
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Registration Statement No. 333-108096, registering an aggregate of 233,333 shares of Common Stock under the 2002 Plan, as amended, and the 2000 Plan, as amended,
as previously filed with the SEC on August 20, 2003;
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5.
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Registration Statement No. 333-117140, registering 2,050,000 shares of Common Stock under the Companys 2004 Stock Incentive Plan (the 2004 Plan),
as previously filed with the SEC on July 2, 2004;
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6.
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Registration Statement No. 333-158521, registering an aggregate of 3,567,662 shares of Common Stock under the 2004 Plan, as amended, and the ESPP, as revised, as
previously filed with the SEC on April 9, 2009; and
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7.
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Registration Statement No. 333-176517, registering 2,093,594 shares of Common Stock under the 2004 Plan, as amended and restated, as previously filed with the SEC
on August 26, 2011.
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On June 19, 2012, pursuant to an Agreement and Plan of Merger, dated as of
April 21, 2012 (the Merger Agreement), by and among the Company, Zeneca Inc., a Delaware corporation (Zeneca), and QAM Corp., a Delaware corporation and wholly owned subsidiary of Zeneca (Merger Sub), Merger
Sub merged with and into the Company, with the Company surviving as a wholly owned subsidiary of Zeneca (the Merger).
As a result of the Merger, the Company has terminated any offering of the Companys securities pursuant to the Registration Statements. In accordance with an undertaking made by the Company in the
Registration Statements to remove from registration, by means of a post-effective amendment, any of the securities which remain unsold at the termination of the offerings, the Company hereby removes from registration all of such securities of the
Company registered but unsold under the Registration Statements, if any.
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8
and has duly caused this Post-Effective Amendment to the Registration Statements to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of San Diego, State of California, on this 19th day of June, 2012.
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ARDEA BIOSCIENCES, INC.
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By:
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/s/ Barry Quart
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Barry Quart
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President and Chief Executive Officer
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Pursuant to the requirements of the Securities Act of 1933, as amended, this Post-Effective
Amendment to the Registration Statements has been signed by the following persons in the capacities and on the dates indicated.
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Signatures
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Title
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Date
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/s/ Barry Quart
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President and Chief Executive
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Barry Quart
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Officer
(Principal Executive Officer)
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June 19, 2012
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/s/ John Beck
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Chief Financial Officer
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John Beck
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(Principal Financial Officer and
Principal Accounting Officer)
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June 19, 2012
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