Trillium Therapeutics Receives Notices of Allowance From U.S. Patent and Trademark Office
October 05 2020 - 7:00AM
Trillium Therapeutics Inc. (“Trillium” or
the “Company”)
(NASDAQ/TSX:TRIL), a clinical
stage immuno-oncology company developing innovative therapies for
the treatment of cancer, announced today that it has received
Notices of Allowance from the United States Patent and Trademark
Office for two patent applications covering the use of SIRPaFc for
the treatment of cancer, U.S. Patent Application No. 13/320,629
(the “629 Application”, exclusively licensed to Trillium) and U.S.
Patent Application No. 15/962,540 (the “540 Application”). Trillium
has two SIRPaFc biologics, TTI-621 and TTI-622, in clinical
development. Both therapeutics target CD47, a “don’t eat me” signal
that cancer cells use to evade immune destruction.
The ‘629 method of use Application provides
coverage for the use of SIRPaFc biologics to treat all CD47+ cancer
cells and tumours, including hematologic and solid cancers.
Counterparts of this application have already been granted in
Japan, Canada and Australia.
The ‘540 Application has claims that cover
TTI-622 composition of matter comprising human SIRPa linked to an
IgG4 Fc region, as well as claims covering pharmaceutical
compositions that contain TTI-622. A composition of matter patent
for TTI-621 (SIRPa linked to an IgG1 Fc) has already been granted
in the U.S. (US 9,969,789) and other countries.
“Intellectual property remains a top priority
for Trillium, and the allowance of these two important patents
further strengthens our position in the SIRPaFc CD47 space,” said
Jan Skvarka, President and Chief Executive Officer of Trillium. “In
addition to our specific composition-of-matter claims covering both
of our CD47-targeting agents, we have expanded our coverage to
embrace the use of the SIRPaFc class of biologics to treat cancer.
We are particularly pleased that the method of use patent also
covers treatment of solid tumors.”
About Trillium Therapeutics
Trillium is an immuno-oncology company
developing innovative therapies for the treatment of cancer. The
Company’s two clinical programs, TTI-621 and TTI-622, target
CD47, a “don’t eat me” signal that cancer cells frequently use to
evade the immune system.
For more information visit: www.trilliumtherapeutics.com.
Caution Regarding Forward-Looking
Information
This press release contains forward-looking
statements within the meaning of applicable United States
securities laws and forward-looking information within the meaning
of Canadian securities laws (collectively, "forward-looking
statements"). Forward-looking statements in this press release
include statements about, without limitation, Trillium’s belief
that the allowed patents will proceed to issue and such allowed
patents strengthen Trillium’s position in the CD47 space. With
respect to the forward-looking statements contained in this press
release, Trillium has made numerous assumptions regarding, among
other things: the effectiveness and timeliness of clinical trials;
and the completeness, accuracy and usefulness of the data. While
Trillium considers these assumptions to be reasonable, these
assumptions are inherently subject to significant scientific,
business, economic, competitive, market and social uncertainties
and contingencies. Additionally, there are known and unknown risk
factors that could cause Trillium's actual results, performance or
achievements to be materially different from any future results,
performance or achievements expressed or implied by the
forward-looking statements contained in this press release. A
discussion of risks and uncertainties facing Trillium appears in
Trillium's Annual Information Form for the year ended December 31,
2019 filed with Canadian securities authorities and on Form 40-F
with the U.S. Securities Exchange Commission, each as updated by
Trillium's continuous disclosure filings, which are available at
www.sedar.com and at www.sec.gov. All forward-looking
statements herein are qualified in their entirety by this
cautionary statement, and Trillium disclaims any obligation to
revise or update any such forward-looking statements or to publicly
announce the result of any revisions to any of the forward-looking
statements contained herein to reflect future results, events or
developments, except as required by law.
Company
Contact:James ParsonsChief Financial
OfficerTrillium Therapeutics Inc. 416-595-0627
x232james@trilliumtherapeutics.com www.trilliumtherapeutics.com
Media Relations:Mike BeyerSam
Brown Inc.312-961-2502mikebeyer@sambrown.com
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