Non-GAAP Financial Measures
In evaluating the operating performance of its business, Verricas management considers non-GAAP loss
from operations, non-GAAP net loss and non-GAAP net loss per share. These non-GAAP financial
measures exclude stock-based compensation charges and non-cash interest expense that are required by GAAP. Verrica believes that non-GAAP loss from operations, non-GAAP net loss and non-GAAP net loss per share provides useful information to both management and investors by excluding the effect of certain non-cash expenses and items that Verrica believes may not be indicative of its operating performance, because either they are unusual and Verrica does not expect them to recur in the ordinary
course of its business, or they are unrelated to the ongoing operation of the business in the ordinary course. Non-GAAP loss from
operations, non-GAAP net loss and non-GAAP net loss per share should be considered in addition to results prepared in accordance with GAAP, but
should not be considered a substitute for, or superior to, GAAP results. Non-GAAP loss from operations, non-GAAP net loss and non-GAAP net loss per share have been reconciled to the nearest GAAP measure in the tables following the financial statements in this press release.
About YCANTH (VP-102)
YCANTH (VP-102) is a proprietary drug-device
combination product that contains a GMP-controlled formulation of cantharidin delivered via a single-use applicator that allows for precise topical
dosing and targeted administration for the treatment of molluscum. YCANTH is the only product approved by the FDA to treat molluscum a common, highly contagious skin disease
that affects an estimated six million people in the United States, primarily children.
In addition, Verrica has successfully completed a Phase 2 study of
VP-102 for the treatment of common warts and a Phase 2 study of VP-102 for the treatment of external genital warts.
About VP-315
VP-315 is a potentially first-in-class oncolytic peptide immunotherapy in development as a
non-surgical treatment option for non-melanoma skin cancers. The Phase 2 trial was initially a three-part, open-label, multicenter, dose-escalation, proof-of-concept study with a safety run-in designed to assess the safety, pharmacokinetics, and efficacy of VP-315 when administered intratumorally to adults with biopsy-proven basal cell carcinoma and was recently amended to two-parts by expanding Part 2. The study is expected to
enroll approximately 80 adult subjects with a histological diagnosis of basal cell carcinoma in at least one eligible target lesion.
Forward-Looking
Statements
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term
is defined in the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as believe, expect, may, plan, potential, will, and similar
expressions, and are based on Verricas current beliefs and expectations. These forward-looking statements include expectations regarding the