By Matt Andrejczak

SAN FRANCISCO (Dow Jones) - CVS Caremark Corp. reported Tuesday first-quarter net income edged down, clipped by new pharmacy-contract costs and acquisition integration expenses.

But the nation's largest drug-store chain boosted its full-year profit outlook by two cents a share, citing the performance of the newly acquired Long Drug stores.

CVS said first-quarter profit declined to $738.4 million, or 50 cents a share, from $745 million, or 51 cents a share, a year earlier. Revenue rose 10% to $23.4 billion.

The company said it would have earned 55 cents a share, excluding $107.5 million of intangible asset amortization related to acquisition activity. Analysts estimated the company to earn 53 cents a share, according to FactSet Research.

CVS shares rose 0.7% to $32.25 by late morning trading.

Earlier this year, CVS renegotiated some pharmacy contracts at lower price rates and bid aggressively to keep others. The drug retailer told investors this would undercut its profit margin this year but the new deals would help business in 2010.

Rhode Island-based CVS (CVS) operates 6,900 stores across the nation and fills the most drug prescriptions nationwide. It acquired Longs Drug Stores last fall, adding 529 stores in California, Arizona, Hawaii and Nevada.

CVS said sales at stores open more than one year - a key gauge of retailer health - rose 3.3% over the same quarter last year. Pharmacy same-store sales rose 4.6% and front-end cash register sales gained 0.7%.

CVS said retail pharmacy network claims processed rose 4.4% to 147.7 million helped by the addition of RxAmerica members and the Maintenance Choice program. Mail service claims rose 3% to 15.7 million during the quarter.

Looking forward, the drug retailer forecast 2009 profit, excluding charges, between $2.55 and $2.63 a share. Its previous forecast had been $2.53 to $2.61 a share.

CVS shares have gained 12% so far this year.