FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

CANADA PENSION PLAN INVESTMENT BOARD 		2. Issuer Name and Ticker or Trading Symbol

IQVIA HOLDINGS INC. [ IQV ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

ONE QUEEN STREET EAST, SUITE 2500 		3. Date of Earliest Transaction (MM/DD/YYYY)

12/4/2018
(Street)

TORONTO ONTARIO, A6 M5C 2W5
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common stock, $0.001 par value per share   12/4/2018     S    1582194   D $123.72   4342572   I   See Footnote   (1) (2)
Common stock, $0.001 par value per share   12/4/2018     S    1582194   D $123.72   1569600   D   (3)  

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
(1)  The disposed securities reported on this row reflect a disposition of indirect ownership by Canada Pension Plan Investment Board ("CPPIB") through its wholly-owned subsidiaries, CPP Investment Board Private Holdings Inc. ("PHI"), CPP Investment Board (USRE III) Inc. ("USRE III") and CPP Investment Board Private Holdings (3) Inc. ("PHI3"). The 1,582,194 shares of the issuer indirectly disposed of by CPPIB consist of 1,541,216 shares sold by PHI, 24,587 shares sold by USRE III, and 16,391 shares sold by PHI3.
(2)  The 4,342,572 shares of the issuer reflected in this row as indirectly owned by CPPIB consist of (i) 4,335,972 shares of the issuer directly owned by PHI and (ii) 6,600 shares of the issuer directly owned by CPPIB MAP Cayman SPC ("MAP"), a wholly-owned subsidiary of CPPIB. PHI has no beneficial ownership over the 6,600 shares of the issuer held indirectly by CPPIB through MAP. USRE III and PHI3 ceased to hold any shares of the issuer as of immediately after the disposition reflected in this row.
(3)  CPPIB directly owns 1,569,600 shares of the issuer and the disposed securities reported on this Form 4 do not include any securities of the issuer directly owned by CPPIB. PHI has no beneficial ownership over the issuer's securities that are directly owned by CPPIB.

Remarks:
PHI is party to a Shareholders Agreement, dated as of May 3, 2016, by and among the issuer and certain shareholders of the issuer. Pursuant to such Shareholders Agreement, PHI and certain other shareholders of the issuer agreed, among other things, to vote their respective shares of the issuer's common stock in favor of certain individuals designated to the issuer's board of directors in accordance with the terms and conditions thereof. As a result of the Shareholders Agreement, the reporting persons may be deemed to be members of a group (the "Group") holding over 10% of the outstanding shares of common stock of the issuer for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended. Each reporting person disclaims beneficial ownership of any securities of the issuer owned by any member of the Group, other than the securities reported in Table I of this Form 4.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
CANADA PENSION PLAN INVESTMENT BOARD
ONE QUEEN STREET EAST
SUITE 2500
TORONTO ONTARIO, A6 M5C 2W5
X

CPP Investment Board Private Holdings, Inc.
ONE QUEEN STREET EAST,
SUITE 2500
TORONTO ONTARIO, A6 M5C 2W5
X


Signatures
BY: /s/ Kathryn J. Daniels Name: Kathryn J. Daniels, Title: Managing Director, Head of Compliance, Legal of Canada Pension Plan Investment Board 12/4/2018
** Signature of Reporting Person Date

BY: /s/ Kathryn J. Daniels Name: Kathryn J. Daniels, Title: Authorized Signatory of CPP Investment Board Private Holdings, Inc. 12/4/2018
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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