Zenith and Newsoara Biopharma Announce Expanded Licensing and Investment
November 15 2021 - 9:55AM
Zenith Capital Corp. (“Zenith” or the “Company”) announced today
that Zenith Epigenetics Ltd. (“Zenith Epigenetics”), a wholly-owned
subsidiary of Zenith Capital, has entered into a licensing
agreement with Newsoara Biopharma Co., Ltd. (“Newsoara”) for Zenith
Epigenetics’ lead compound, ZEN-3694, in Asia excluding Middle East
and North Africa (“MENA”), India, and ten Eurasian countries (the
“Territories”). Under the terms of the agreement, Newsoara will
have the rights to develop, market, and distribute ZEN-3694 for all
indications in the Territories. Zenith will receive an upfront
payment of US$3.5 million, sales-based milestones and single digit
royalties.
Concurrent with the execution of the license
agreement, Newsoara has entered into a subscription agreement to
subscribe for 1.5 million units at a price of US$1.00 per unit, and
Newsoara also agreed to subscribe for an additional 10 million
units of Zenith by way of completing ZEN-3694 development programs
with a budget of $10 million over the next 15 months. Each unit
(“Unit”) shall be comprised of one common share and one-half of a
common share purchase warrant. Each whole warrant shall be
exercisable into one common share at US$1.00 for a period of two
years from the date of the subscription
agreement. “We are very pleased to further
expand our partnership with Newsoara to introduce the therapeutic
potential of ZEN-3694 to additional Asian markets,” stated Donald
McCaffrey, President and CEO of Zenith. “ZEN-3694 is a leading and
differentiated BET inhibitor now having shown clinical proof of
concept in two solid tumor indications with significant unmet need,
metastatic castration-resistant prostate cancer and metastatic
triple negative breast cancer. This additional financing will
support advancing these programs towards registration enabling
studies for these indications in collaboration with our partner
Newsoara.”
About Newsoara
Newsoara is a biotech company based
in Shanghai, China with research laboratories in the
Suzhou BioBAY focusing on novel drug research and development to
address unmet medical needs in patients with oncology, autoimmune,
respiratory, and metabolic diseases. Newsoara has licensed
development and commercialization rights to ZEN-3694 for China,
Hong Kong, Taiwan, Macau and Asia excluding MENA (Middle East and
North Africa), India and ten Eurasian countries.
About Zenith
Zenith Capital Corp. is a biotechnology
investment company originally spun out of Resverlogix Corp. (TSX:
RVX) in 2013. Zenith Epigenetics Ltd., a wholly-owned subsidiary of
Zenith Capital Corp., is a clinical stage biotechnology company
focused on the discovery and development of novel therapeutics for
the treatment of cancer and other disorders with significant unmet
medical need. Zenith Epigenetics is developing various novel
combinations of BET inhibitors with other targeted agents. The lead
compound, ZEN-3694, is in clinical development for:
- Metastatic castration-resistant prostate cancer (“mCRPC”) in
combination with androgen receptor inhibitor, enzalutamide
(XTANDI), with Astellas and Newsoara as collaborators.
- Triple Negative Breast Cancer (“TNBC”) in combination with the
PARP inhibitor TALZENNA with Pfizer as a collaborator.
- Androgen receptor independent mCRPC in combination with immune
checkpoint inhibitor KEYTRUDA and XTANDI with University of
California, San Francisco as a collaborator.
- Ovarian cancer in combination with immune-checkpoint
inhibitors, nivolumab and ipilimumab in collaboration with the
National Cancer Institute.
- Nut midline carcinoma in combination with chemotherapy in
collaboration with the National Cancer Institute.
For further information, please
contact:Investor Relations &
Communications
Zenith EpigeneticsPhone: 587-390-7865Email:
info@zenithepigenetics.com Website:
www.zenithepigenetics.com
This news release may contain certain
forward-looking information as defined under applicable Canadian
securities legislation, that are not based on historical fact,
including without limitation statements containing the words
"believes", "anticipates", "plans", "intends", "will", "should",
"expects", "continue", "estimate", "forecasts" and other similar
expressions. In particular, this news release includes forward
looking information relating to the license and subscription
agreements with Newsoara, the introduction of ZEN-3694 by Newsoara
to Asian markets and the potential role of ZEN-3694 in the
treatment of cancer and other disorders. Our actual results, events
or developments could be materially different from those expressed
or implied by these forward-looking statements. We can give no
assurance that any of the events or expectations will occur or be
realized. By their nature, forward-looking statements are subject
to numerous assumptions and risk factors including those discussed
in our most recent MD&A which are incorporated herein by
reference and are available through SEDAR at www.sedar.com. The
forward-looking statements contained in this news release are
expressly qualified by this cautionary statement and are made as of
the date hereof. Zenith disclaims any intention and has no
obligation or responsibility, except as required by law, to update
or revise any forward-looking statements, whether as a result of
new information, future events or otherwise.
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