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Tetra Bio Pharma Inc

Tetra Bio Pharma Inc (TBP)

0.215
0.00
(0.00%)
Closed November 03 4:00PM

Empower your portfolio: Real-time discussions and actionable trading ideas.

Key stats and details

Current Price
0.215
Bid
0.21
Ask
0.215
Volume
-
0.00 Day's Range 0.00
0.215 52 Week Range 0.215
Previous Close
0.215
Open
-
Last Trade
Last Trade Time
Average Volume (3m)
-
Financial Volume
-
VWAP
-

TBP Latest News

Tetra Bio-Pharma Announces Closing of Bought Deal Offering

Tetra Bio-Pharma Announces Closing of Bought Deal Offering Canada NewsWire OTTAWA, ON, May 17, 2021 /NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRE SERVICES OR DISSEMINATION IN THE UNITED...

Tetra Bio-Pharma Announces $10 Million "Bought Deal" Public Offering

Tetra Bio-Pharma Announces $10 Million "Bought Deal" Public Offering Canada NewsWire TORONTO, May 10, 2021 /NOT FOR DISTRIBUTION TO THE U.S. NEWSWIRE OR FOR DISSEMINATION IN THE UNITED...

Tetra Bio-Pharma Announces Closing of Bought Deal Offering

Tetra Bio-Pharma Announces Closing of Bought Deal Offering Canada NewsWire OTTAWA, ON, March 2, 2021 /NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRE SERVICES OR DISSEMINATION IN THE UNITED...

Tetra Bio-pharma Inc. Announces Upsizing of Previously Announced Offering

Tetra Bio-pharma Inc. Announces Upsizing of Previously Announced Offering Canada NewsWire OTTAWA, ON, Feb. 23, 2021 NOT FOR DISTRIBUTION TO U.S. NEWSWIRE SERVICES OR DISSEMINATION IN THE UNITED...

Tetra Bio-Pharma Inc. Announces $10 Million Bought Deal Offering of Units

Tetra Bio-Pharma Inc. Announces $10 Million Bought Deal Offering of Units Canada NewsWire OTTAWA, ON, Feb. 22, 2021 /NOT FOR DISTRIBUTION TO U.S. NEWSWIRE SERVICES OR DISSEMINATION IN THE UNITED...

Tetra Bio-Pharma Inc. Announces Closing of Non-Brokered Private Placement

Tetra Bio-Pharma Inc. Announces Closing of Non-Brokered Private Placement Canada NewsWire OTTAWA, ON, Feb. 3, 2021 OTTAWA, ON, Feb. 3, 2021 /CNW Telbec/ - Tetra Bio-Pharma Inc. ("Tetra...

Tetra Bio-Pharma Inc. Acquires Common Shares of Mondias Natural Products Inc.

Tetra Bio-Pharma Inc. Acquires Common Shares of Mondias Natural Products Inc. Canada NewsWire OTTAWA, ON, Nov. 2, 2020 OTTAWA, ON, Nov. 2, 2020 /CNW Telbec/ - Tetra Bio-Pharma...

Tetra Bio-Pharma and Mondias enter into final agreement for the purchase of Lumiera Health Innovation Inc.

Tetra Bio-Pharma and Mondias enter into final agreement for the purchase of Lumiera Health Innovation Inc. Canada NewsWire MONTREAL, Aug. 17, 2020 MONTREAL, Aug. 17, 2020 /CNW Telbec/ -Β Mondias...

Tetra Bio-Pharma Announces Expected Effective Date of Listing on TSX of its Common Shares and Warrants

Tetra Bio-Pharma Announces Expected Effective Date of Listing on TSX of its Common Shares and Warrants Canada NewsWire OTTAWA, ON, July 30, 2020 /NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRE...

Tetra and Mondias jointly announce the acquisition of Tetra's subsidiary, Lumiera, by Mondias to create a new growth platform

Tetra and Mondias jointly announce the acquisition of Tetra's subsidiary, Lumiera, by Mondias to create a new growth platform Canada NewsWire MONTREAL, July 23, 2020 Allowing Tetra to focus...

PeriodChangeChange %OpenHighLowAvg. Daily VolVWAP
1000.2150.2150.21500CS
4000.2150.2150.21500CS
12000.2150.2150.21500CS
26000.2150.2150.21500CS
52000.2150.2150.21500CS
156000.2150.2150.21500CS
260-0.01-4.444444444440.2250.690.1851680490.35640147CS

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TBP Discussion

View Posts
Netcool Netcool 5 months ago
$TBPMQ waking up?
πŸ‘οΈ0
fung_derf fung_derf 8 months ago
Well THIS is certainly interesting.....you want to sue a poster for giving you misinformation in order to promote a stock price?? And shockingly, you lost money in ANOTHER penny stock??!!

OK , I am posting to the lawyers who always looking to sue the companies..

I want to sue this loser CEO of TBPMF , and his friend ..I don't remember this friend name now , but I invested at the time because of this friend pumping,
I do remember his face from many pumping videos he made before he sold his shares , and I will look until I do find his name..
They both pumped this stock , and then I believe they sold..
I think I lost couple hundreds thousand of doll , and I want to go after them.. I believe they both dishonest , and I am done with this type of people..

If any lawyer representative is reading here , please contact me..

I am done with crooks..I want to go after them both now !!!!

All IMO...
πŸ‘οΈ0
Renee Renee 1 year ago
TBPMF changed to TBPMQ, bankruptcy:

https://otce.finra.org/otce/dailyList?viewType=Symbol%2FName%20Changes
πŸ‘οΈ0
fung_derf fung_derf 1 year ago
How many times can you do this?
πŸ‘οΈ0
fung_derf fung_derf 1 year ago
Here too??? And look who you're talking with?
Lemme guess, she has another kid saved by this drug?
πŸ‘οΈ0
AJ Freely AJ Freely 1 year ago
$TBPMF - Tetra Bio-Pharma Voluntary Bankruptcy
Ontario Securities Commission rejected an application for a Management Cease Trade Order and prevented them from negotiating any securities to continue to finance the corporation and blocked Tetra from paying debt with shares.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Not on OTC. It trades under ticker TBPMF.

21 months ago CEO told on video 2 major stories. One was for Reduvo for which they applied 28 (!!!) Months ago for market access. 28 months!! What's wrong??? No info!!!

18 months ago he told us they started with FDA a Reborn trial which should replace Opioid for pain control. 18 months not 1 single info.

Trading halted or not, it is a dead beaten dog. Such simple company without business can't get an commercial audit done? Before i bought shares info's were flowing. Results were very promising and I thought we
have a solution for the Opiod Crisis.

I was wrong! Take care!
πŸ‘οΈ0
GARYM1 GARYM1 2 years ago
I thought this was halted
πŸ‘οΈ0
d0lphint0m d0lphint0m 2 years ago
For sure

I posted it to show you the guy.
👍️ 1
misiu143 misiu143 2 years ago
Isn’t that a very old video ???
👍️ 1
d0lphint0m d0lphint0m 2 years ago


I found this video.i think the guy in the black hat is who you are referring to.
👍️ 1
jcamp jcamp 2 years ago
News….more funding from Canada without the dilution
πŸ‘οΈ0
treedoc treedoc 2 years ago
Pink market trading now. Nice. Forward
πŸ‘οΈ0
Netcool Netcool 2 years ago
$TBPMF show me the DIN.
πŸ‘οΈ0
misiu143 misiu143 2 years ago
OK , I am posting to the lawyers who always looking to sue the companies..

I want to sue this loser CEO of TBPMF , and his friend ..I don't remember this friend name now , but I invested at the time because of this friend pumping,
I do remember his face from many pumping videos he made before he sold his shares , and I will look until I do find his name..
They both pumped this stock , and then I believe they sold..
I think I lost couple hundreds thousand of doll , and I want to go after them.. I believe they both dishonest , and I am done with this type of people..

If any lawyer representative is reading here , please contact me..

I am done with crooks..I want to go after them both now !!!!

All IMO...
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
The 2 years for Reduvo are now completed. A simple drug approval takes in Canada 2 years and no end in sight.
The Reborn trial completed 1, 5 years without any comments and results. Is the trial still running or has it been stopped?

They got recently about 10 Mio$ as a loan. For what?
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
We get a not atypical question from Health Canada. If a risk management plan is not atypical, why haven't we delivered such plan not 2 years ago? Now we don't have such plan otherwise we would have provided it already 2 years ago. I have no idea how complex such plan is, but we can assume they will need at least 1 months and then.....

We end up March 23.
What professionals are these guys? Shame on them!! 2 years sleeping on the shelf and another round and then another??
And Reborn? Is it dead? 18 months no info!!
πŸ‘οΈ0
Buellersback Buellersback 2 years ago
REDUVOβ„’ Marketing Approval on the Right Path

12/22/2022
Second Clarifax received from Health Canada.
MONTREAL, Dec. 22, 2022 /CNW/ - Tetra Bio-Pharma Inc. ("Tetra" or the "Company") (TSX: TBP) (OTCQB: TBPMF) (FRA: JAM1) a leader in cannabinoid-derived drug discovery and development is providing its shareholders with another regulatory update on the REDUVOβ„’ New Drug Submission (NDS). The last update was provided on November 18, 2022.

Tetra Bio-Pharma Logo (CNW Group/Tetra Bio-Pharma Inc.)

On December 21, 2022, the Company received a second Clarification Request (Clarifax) from Health Canada regarding the product's Risk Management Plan, which is not atypical for a controlled substance drug. The Company will be submitting the response to Health Canada within the allowed timeframe. The Company cannot comment on Health Canada's response timelines. Questions/feedback from Health Canada are received as the review of the dossier progresses through different review streams.

About REDUVOβ„’

REDUVOβ„’ is a soft gel capsule used to treat chemotherapy-induced nausea and vomiting (CINV). It is also used to treat weight loss and severe nausea in people living with HIV infection. The active pharmaceutical ingredient in REDUVOβ„’ is dronabinol, also known as THC, a synthetic form of the active natural substance in cannabis. REDUVOβ„’ 5-year cumulative gross sales expected to reach $121M.

About Tetra Bio-Pharma

Tetra Bio-Pharma (TSX: TBP) (OTCQB: TBPMF) (FRA:JAM1) is a leader in cannabinoid-derived drug discovery and development with a FDA and a Health Canada cleared clinical program aimed at bringing novel prescription drugs and treatments to patients and their healthcare providers. Their evidence-based scientific approach has enabled them to develop a pipeline of cannabinoid-based drug products for a range of medical conditions, including pain, inflammation, and oncology. With patients at the core of what they do, Tetra Bio-Pharma is focused on providing rigorous scientific validation and safety data required for inclusion into the existing biopharma industry by regulators, physicians and insurance companies.

Neither the TSX Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Exchange) accepts responsibility for the adequacy or accuracy of this release.

Forward-looking statements

Some statements in this release may contain forward-looking information. All statements, other than of historical fact, that address activities, events or developments that the Company believes, expects or anticipates will or may occur in the future (including, without limitation, statements regarding potential acquisitions and financings) are forward-looking statements. Forward-looking statements are generally identifiable by use of the words "may", "will", "should", "continue", "expect", "anticipate", "estimate", "believe", "intend", "plan" or "project" or the negative of these words or other variations on these words or comparable terminology. Forward-looking statements are subject to a number of risks and uncertainties, many of which are beyond the Company's ability to control or predict, that may cause the actual results of the Company to differ materially from those discussed in the forward-looking statements. Factors that could cause actual results or events to differ materially from current expectations include, among other things, without limitation, the inability of the Company to obtain sufficient financing to execute the Company's business plan; competition; regulation and anticipated and unanticipated costs and delays, the success of the Company's research and development strategies, including the success of this product or any other product, the applicability of the discoveries made therein, the successful and timely completion and uncertainties related to the regulatory process, the timing of clinical trials, the timing and outcomes of regulatory or intellectual property decisions and other risks disclosed in the Company's public disclosure record on file with the relevant securities regulatory authorities. Although the Company has attempted to identify important factors that could cause actual results or events to differ materially from those described in forward-looking statements, there may be other factors that cause results or events not to be as anticipated, estimated or intended. Readers should not place undue reliance on forward-looking statements. The forward-looking statements included in this news release are made as of the date of this news release and the Company does not undertake an obligation to publicly update such forward-looking statements to reflect new information, subsequent events or otherwise unless required by applicable securities legislation.

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/reduvo-marketing-approval-on-the-right-path-301709009.html

SOURCE Tetra Bio-Pharma Inc.
πŸ‘οΈ0
Buellersback Buellersback 2 years ago
Let’s hope approval happens!
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TheBigTicket TheBigTicket 2 years ago
https://ir.tetrabiopharma.com/newsroom/press-releases/news-details/2022/REDUVO-Marketing-Approval-on-the-Right-Path/default.aspx
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Good, if you are happy with bla bla pr. Since June 22 we got nothing with any substance. 2 years - no Reduvo- approval. 1,5 years no info about Reborn trial.
The only positive, I can take, is the loan we got from a good longterm investor. They are not giving tetra a huge loan without promising background info.
πŸ‘οΈ0
Buellersback Buellersback 2 years ago
Good to see a few PRs.
πŸ‘οΈ0
TheBigTicket TheBigTicket 2 years ago
https://ir.tetrabiopharma.com/newsroom/press-releases/news-details/2022/Tetra-Bio-Pharma-Announces-Results-of-Artificial-Intelligence-Study-of-ARDS-003-Combined-with-Favipiravir/default.aspx
πŸ‘οΈ0
TheBigTicket TheBigTicket 2 years ago
https://cdn.jwplayer.com/previews/4pfK5DCs
πŸ‘οΈ0
Buellersback Buellersback 2 years ago
Good stuff. Finally a sign of life.
πŸ‘οΈ0
treedoc treedoc 2 years ago
Should be a fairly easy fix.
β€œOn November 16, the Company received a Clarification Request (Clarifax) from Health Canada regarding the product labels.”
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
What kind of clowns are in Canada Health? They need 2 years to bring 1 question foreward and then the delinquent has to answer within 2 days. If correct, then its a good joke.
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jcamp jcamp 2 years ago
Request for Clarification (Clarifax)
A Clarifax is issued when revisions and/or clarifications regarding the CTA or CTA-A are required. Requests for clarification that are issued during screening should be responded to within 2 calendar days [C.05.009]. A Rejection Letter will be issued if a timely response to a Clarifax has not been provided.
πŸ‘οΈ0
jcamp jcamp 2 years ago
Sounds promising. Tetra has two calendar days to respond. If that’s their only question it bodes well.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Great, after 23 months the first question. How long will it take for the second question? At least one started to read the application. See you end of 2023? Bravo Canada Health - it is alive!!
πŸ‘οΈ0
TheBigTicket TheBigTicket 2 years ago
https://ir.tetrabiopharma.com/newsroom/press-releases/news-details/2022/Tetra-Bio-Pharma-Provides-Update-on-Its-REDUVO-New-Drug-Submission/default.aspx
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Does anyone know more about the financing by Alpha Blue Ocean? Why should one a "dead cat" borrow money without interest, or at all? Credit convertible into worthless shares? Getting worthless warrants for 0,035$? No one would ever do so unless he/she knows Reborn is becoming a winner.
Tetra already knows very well whether Reborn is a success or not but has obviously problems filling the trial, or FDA makes some problems as usual for tiny biotechs.

Maybe TETRA will still become a winner. Reborn works, but that doesn't mean that TETRA will succeed; too many enemies are waiting to eat it.
πŸ‘οΈ0
jcamp jcamp 2 years ago
Reduvo will keep us in business. Very important. No new news on Reborn.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Reduvo has some importance, but those who invested in Tetra are not here because of Reduvo but for the reborn success. Reborn is the key for tetra, Reduvo is just a tiny matter of support, but even this didn't come along in 23 months.

Any clue where Reborn is after 16 months?
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Here is my letter, which didn't get any reply:

Dear Natalie,

I hope you are in a much better condition than Tetra. I wonder what you think you can tell me:

Initially, your CEO was expecting the Reduvo approval for latest end of 2021. I checked in the meantime the performance of Health Canada and found that in the worst case, the approval process for a drug took 24 months. We will reach the worst case, 24 months, in December 2022. Does your company know that we will even be the new record and take longer than 24 months?
The intermediate results for Reborn - FDA trial- were planned for June 22. You modified the trial twice to be faster than initially seen. We are now 16 months into the trials without any report for results. The performance of Reborn can be seen daily, but no indications are given about enrollment (done or not?) and performance (within expectations or not).

We are approaching the last resistance before we fall over the cliff down to 0.006. Does the CEO want us to fall over the cliff? I trust, Reborn is working, but maybe you can't manage the enrollment. Perhaps something went very wrong?
Maybe the CEO feel burnt after all his promises last year in June failed so dramatically. Even if he doesn't want anymore give predictions some info could keep us alive such following messages:

We still wait for the approval. So far no negative indications that it will not take place.
The Reborn trial is smoothly running; enrollment is very slow, but we have managed so far xy %. After complete enrollment, it will take us another xy months for results.

I think your CEO should consider that people like me and many others invested in Tetra based on excellent preliminary results. We need to come back to a climate of hope and trust.

Could you please let your CEO know?

kindest regards
πŸ‘οΈ0
jcamp jcamp 2 years ago
That’s hilarious. I’ve spoke with them on multiple occasions. Most recently Oct. 13th.
They’re definitely still in business. They have enough $ to get them to April. Still counting on the DIN to start bringing in revenue. Unfortunately they couldn’t speak to Canadas delay.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
I was writing twice to the company. No reply. I was calling, no one takes phone. Conclusion? Soon they will delist - they are dead and we need opiate for the pain.
Happy bagholding.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
We are approaching several milestones:
1) soon we have 2 years completed for waiting for Reduvo approval. CEO is speechless!
2) soon we will be back at alltime low 0.01. CEO is paralyzed!
3) soon Reborn trial is running 18 months. Is it running at all? CEO provides no information.
4) no information about projects and joint ventures? CEO doesn't care about TBP otherwise he would at least try to build trust and confidence with the shareholder. Or?? Does he have an other agenda?
With the little knowledge of today, I would trust the medicine, but no way to trust management. No way to trust that any medicine gets approved despite its performance as opioid makes too much money. Who cares on suffering or dead people as long as BP makes Billions $.
Only sick people are good for business. Death is collateral damage, part of business.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
In 3 months we have the 24 months completed. Bravo Canada Health. Another crooked organisation. Never approve something what helps people. The same story like with FDA
πŸ‘οΈ0
Buellersback Buellersback 2 years ago
IF the DIN is approved by Health Canada, PPS will go way higher than 5 cents. I now consider TBPMF a lotto play.
πŸ‘οΈ0
Netcool Netcool 2 years ago
Things are starting to come together as well as new developments. Looking forward to the Reduvo DIN as we all are, LOL. Still under the radar so great buying opportunity! Go $TBPMF.
πŸ‘οΈ0
jcamp jcamp 2 years ago
Tetra Bio-Pharma, which trades on the Toronto Stock Exchange and the OCTQB exchange in the U.S., said last week it’s agreed to issue up to $6 million worth of unsecured debentures and stock purchase warrants to London-based investment firm Alpha Blue Ocean Group.

The offering is expected to occur in 15 tranches for total net proceeds of about $5.4 million.

Chief commercial officer Steeve Neron said the deal should provide enough cash to keep the company afloat for the next 14 to 15 months as it awaits the green light from Health Canada to sell one of its key products – a gel capsule used to treat chemotherapy-induced nausea and vomiting in cancer patients and weight loss and severe nausea in patients with HIV infections.
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
New terms and first closing of financing with Alpha Blue!

Apart from the increase of the financing volume from 6 to 10 Mio $, the following sentence seems to me to be indirect info:
"The Company intends to use the net proceeds of the Financing to finance the manufacturing costs of its QIXLEEF drug candidate."

Is this a hint that Reduvo approval is finally coming? Is this the reason for increasing the volume from 6 to 10 Mio$?
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
Thank you for sharing this video.

We all hear and know about Opioide crisis. We have heard extremely promising first results of the Tetra product. It will in many years find its way to the market. Not much doubt.

I am with Leronlimab for more than 5 years. Every expert knows how phantastic this drug works for Covid, Cancer, HIV, TNBC, NASH and many other diseases. It was successful in Phase3 and 2 trials. And? No way to find its way to the market. Big Pharma will not allow to get its business destroyed and FDA collaborates perfectly.

Let's look at Tetra's Reborn trial. It runs for more than 1 year and Tetra has even not reported interim results. There is no way to bypass BP. FDA will find ways to delay for many years, no matter how great Tetra's products are working.

Whatever Gay told us in June 21 was wrong. Yes, the Tetra product is working and is needed desperately but BP will not allow to get it to market. Maybe the new JV can help but still it will take many years.

I invested 2021 because Reborn trial and coming PIN. I was wrong like with Leronlimab. In both my investments were years too early. Gay does what Nader did - telling not the whole true story about great medicine.
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Zuess421 Zuess421 2 years ago
https://thebalancingact.com/a-new-trend-in-pain-management/#.Ywy7jY2QWrM.linkedin
πŸ‘οΈ0
Zuess421 Zuess421 2 years ago
Tetra has been halted for pending news.
πŸ‘οΈ0
jcamp jcamp 2 years ago
Tetra Collaborates with Cellvera to Develop a Potential Oral Combination Treatment for COVID-19 Patients
πŸ‘οΈ0
Emergcy Emergcy 2 years ago
We continue to get served one Nothingburger after the other one. Many "news", but all are irrelevant. What is relevant? We know it:

X) PIN for Reduvo! Why don't we hear anything about it? The approval process already takes 20 months, and no update.
X) What is with Reborn going on? Guy promised us for June 22 interim results. The trial started on June 21. We are in the 15th month, and no results? Is it running at all?

Guy had a big mouth on June 21, but then he disappeared and sent us unimportant Nothingburgers. What is going on?
πŸ‘οΈ0
sonny4me sonny4me 2 years ago
So, the whole bio sector is getting screwed over by big pharma.
πŸ‘οΈ0
Buellersback Buellersback 2 years ago
Interesting article explaining PPS woes for many biotech companies like TBPMF:

Big Pharma Won't Bail Out Battered Biotech -- Heard on the Street -- WSJ
7:00 am ET June 30, 2022 (Dow Jones) Print
By David Wainer


The stock market might be in the doldrums, but the biotechnology index has fallen off a cliff. One measure says it all: Dozens of publicly traded biotechs have dropped so much that they are now valued below the amount of cash they have in the bank.

Some healthcare investors have been pointing to that trend as a sign things have started to bottom. The argument goes that biotech has become so cheap that big pharma -- staring down a patent cliff and armed with hundreds of billions of dollars of dry powder for acquisitions -- will come to the rescue. Indeed, a popular biotech exchange-traded fund, the SPDR S&P Biotech ETF, has rebounded by around 20% from its recent lows.

That analysis paints with too broad a brush. Many of the companies now trading below cash are likely to go out of business in a macroeconomic environment in which their key input cost -- money -- is rising. To an even greater degree than high-growth tech companies such as Shopify or Roblox, biotech struggles in a rising interest-rate environment because many companies don't have any real revenue streams and don't expect to have a product in the market for years. Sadly for both investors and patients, clinical trials move slowly.

That problem has been exacerbated by a biotech bubble in recent years as too many early-stage companies went public. In 2021, the peak bubble year, 111 biotechs had initial public offerings in the U.S., topping the previous peak of 91 in 2020. Some of those companies are still conducting preclinical trials, meaning they haven't even begun testing their therapies on humans.

Sio Gene Therapies, with its shares down 87% in the past year, is an example of a company trading at a negative enterprise value. Sio Gene's market capitalization is $27 million, even though it had $65 million in the bank as of the end of the first quarter.

But Sio Gene is anything but a bargain. The company has terminated its gene therapy licensing agreements with the University of Massachusetts, is quickly running out of cash, and has fired much of its staff. Because a company like Sio Gene is effectively locked out of the capital markets these days, it needs to find a buyer to bail it out. The company hired SVB Securities in late April to help it explore a sale. Whether it can survive in some form remains to be seen.

Sio Gene isn't alone. Fierce Biotech, a news outlet focused on the industry, started a layoff tracker this year, and it looks scary. In the first week of June, for instance, oncology biotech Atreca announced plans to cull a quarter of its workforce and stem-cell developer Athersys said it is cutting 70% of its staff. And the list goes on.

So when will the bleeding stop? For Les Funtleyder, a healthcare investor at E Squared Capital Management, the sector as a whole can't really begin to rebound until it is clear that the Federal Reserve is finished raising rates. As of now, traders are pricing in rate cuts later next year, so a recovery could start early next year, he says. Pharma companies, Mr. Funtleyder says, aren't particularly focused on valuations. What they are focused on is the science and whether the business is a strategic fit.

Of course the market rout leaves some solid biotech businesses trading at bargain prices. That means the deal pace will probably pick up this year, especially in the crowded oncology space. Ipsen has agreed to acquire Epizyme for $247 million, and Bristol-Myers Squibb said it would buy Turning Point Therapeutics for $4.1 billion. Both are cancer plays. While the Turning Point deal reflected a premium, the purchase price was still below last year's high. Much of the most recent strength in the biotechnology sector has been related to speculation that Merck & Co. might buy Seagen, a company that could fetch about $40 billion.

But pharma companies are looking for needles in the haystack, not the haystack itself. That means more pain could still be coming for biotech investors. Big pharma won't be there to help.

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