biOasis Discovers the Keys to Transcend to Advance Its Program for the Delivery of Therapeutics Across the Blood-Brain Barrier
April 24 2014 - 9:00AM
Marketwired
biOasis Discovers the Keys to Transcend to Advance Its Program for
the Delivery of Therapeutics Across the Blood-Brain Barrier
This Represents A Major Finding For the Company, Its Partners,
Potential Partners and Shareholders
VANCOUVER, BRITISH COLUMBIA--(Marketwired - Apr 24, 2014) -
BIOASIS TECHNOLOGIES INC. (OTCQX:BIOAF)(TSX-VENTURE:BTI), a
pioneering biopharmaceutical company focused on overcoming the
limitations of therapeutic drug delivery across the blood-brain
barrier, has identified a new family of peptides that conserve the
brain shuttling properties of Transcend. Transcend is biOasis'
proprietary vector which has the function of shuttling molecules
across the blood-brain barrier. In side-by-side comparisons, these
new peptide vectors are more efficient than the native, full-size
Transcend molecule at delivering cargo to the brain.
This new family of peptides is able to shuttle a variety of
therapeutic and biologics into the brain and their transport is not
limited by the size of the transported therapeutic or its
composition. This family, the second generation of Transcend,
offers multiple advantages compared to Transcend. For example, the
costs of production are extremely low as the peptides can be easily
synthesized and a wide variety of peptide-cargo conjugates with
different applications to a range of diseases can be produced
simply and predictably. The peptide vectors are particularly
well-suited to coupling to small molecule chemotherapeutics and
other drugs. Thus development of new drugs using these new shuttle
vectors can be accomplished more quickly and at much lower costs.
This new family of novel chemical entities will provide a strong
patent position for the company and its current and future
partners.
Professor Wilfred Jefferies, biOasis' founding scientist states,
"After several years of innovation based on Transcend, our team has
identified a new class of small carriers that can shuttle drugs
across the blood-brain barrier allowing them to enter and
distribute in the brain. In preclinical animal models the peptide
vector-conjugates have shown remarkable efficacy. The discovery and
translation of these new carrier entities into novel therapeutics
provides a glimpse into the future treatment of Neurological
Disorders."
About Transcend
Transcend offers the creation of a new class of drugs that can
cross the blood-brain barrier to address unmet medical needs in the
treatment of brain metastatic cancer and other brain disorders,
such as neurodegeneration and metabolic disease. The blood-brain
barrier represents the single greatest challenge in treating
diseases and other disorders within the brain. Diseases such as
cancer are readily treated in many areas of the body, but drugs
designed to treat cancer simply cannot penetrate the blood- brain
barrier. The ability to more effectively permeate the blood-brain
opens the door for the creation of new drugs designed to treat a
wide variety of neurological diseases and disorders. Additionally,
Transcend offers the potential to take existing clinically approved
drugs that are near their end of patent life and extend them.
About biOasis
biOasis Technologies Inc. is a biopharmaceutical company
headquartered in Vancouver, Canada. Based on Transcend, biOasis
proprietary brain delivery platform, the company is focused on
creating new drugs that can cross the blood-brain barrier to
address unmet medical needs in the treatment of brain diseases such
as neurodegeneration, metastatic cancer and metabolic diseases.
biOasis trades on the OTCQX under the symbol "BIOAF" and on the TSX
Venture Exchange under the symbol "BTI". For more information about
the company please visit www.bioasis.ca.
Forward Looking Statements
Certain statements in this press release contain forward-looking
statements within the meaning of the Private Securities Litigation
Reform Act of 1995 or forward-looking information under applicable
Canadian securities legislation that may not be based on historical
fact, including without limitation statements containing the words
"believe", "may", "plan", "will", "estimate", "continue",
"anticipate", "intend", "expect" and similar expressions. Such
forward-looking statements or information involve known and unknown
risks, uncertainties and other factors that may cause our actual
results, events or developments, or industry results, to be
materially different from any future results, events or
developments express or implied by such forward-looking statements
or information. Such factors include, among others, our stage of
development, lack of any product revenues, additional capital
requirements, risk associated with the completion of clinical
trials and obtaining regulatory approval to market our products,
the ability to protect our intellectual property, dependence on
collaborative partners and the prospects for negotiating additional
corporate collaborations or licensing arrangements and their
timing. Specifically, certain risks and uncertainties that could
cause such actual events or results expressed or implied by such
forward-looking statements and information to differ materially
from any future events or results expressed or implied by such
statements and information include, but are not limited to, the
risks and uncertainties that: products that we develop may not
succeed in preclinical or clinical trials, or future products in
our targeted corporate objectives; our future operating results are
uncertain and likely to fluctuate; we may not be able to raise
additional capital; we may not be successful in establishing
additional corporate collaborations or licensing arrangements; we
may not be able to establish marketing and the costs of launching
our products may be greater than anticipated; we have no experience
in commercial manufacturing; we may face unknown risks related to
intellectual property matters; we face increased competition from
pharmaceutical and biotechnology companies; and other factors as
described in detail in our filings with the Canadian securities
regulatory authorities at www.sedar.com. Given these risks and
uncertainties, you are cautioned not to place undue reliance on
such forward-looking statements and information, which are
qualified in their entirety by this cautionary statement. All
forward-looking statements and information made herein are based on
our current expectations and we undertake no obligation to revise
or update such forward- looking statements and information to
reflect subsequent events or circumstances, except as required by
law.
On Behalf of the Board of Directors
Rob Hutchison Chairman & CEO
"Neither the TSX
Venture Exchange nor its Regulation Services Provider (as that term
is defined in the policies of the TSX Venture Exchange) accepts
responsibility for the adequacy or accuracy of this release"
biOasis Technologies Inc.Rob HutchisonChairman &
CEO778-383-3280rob@bioasis.caLiolios Group, Inc.Ron BothSenior
Managing Director949-574-3860BTI@liolios.com
Bioasis Technologies (CE) (USOTC:BIOAF)
Historical Stock Chart
From Nov 2024 to Dec 2024
Bioasis Technologies (CE) (USOTC:BIOAF)
Historical Stock Chart
From Dec 2023 to Dec 2024