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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 6-K
REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES
EXCHANGE ACT OF 1934
Date of Report: November 7, 2024
Commission File Number: 001-40377
VALNEVA SE
(Translation of registrant's name into English)
6 rue Alain Bombard
44800 Saint-Herblain, France
(Address of principal executive office)
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F ☒ Form 40-F ☐
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):
Note: Regulation S-T Rule 101(b)(1) only permits the submission in paper of a Form 6-K if submitted solely to provide an
attached annual report to security holders.
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):
Note: Regulation S-T Rule 101(b)(7) only permits the submission in paper of a Form 6-K if submitted to furnish a report or other
document that the registrant foreign private issuer must furnish and make public under the laws of the jurisdiction in which the
registrant is incorporated, domiciled or legally organized (the registrant's "home country"), or under the rules of the home
country exchange on which the registrant's securities are traded, as long as the report or other document is not a press release, is
not required to be and has not been distributed to the registrant's security holders, and, if discussing a material event, has already
been the subject of a Form 6-K submission or other Commission filing on EDGAR.
On November 7, 2024, the Registrant announced its results from the nine months ended September 30, 2024 and issued a press
release and unaudited interim condensed consolidated financial statements, copies of which are attached hereto as Exhibits 99.1,
and 99.2, respectively, and incorporated herein by reference. The information contained in this Form 6-K, including Exhibits
99.1 and 99.2, is hereby incorporated by reference into the registrant's Registration Statement on Form F-3 (File No.
333-266839).
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| Unaudited Interim Condensed Consolidated Financial Statements as at September 30, 2024 and for the three months ended September 30, 2024 |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its
behalf by the undersigned, thereunto duly authorized.
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A EUROPEAN COMPANY (SOCIETAS
EUROPAEA) WITH A BOARD OF DIRECTORS
Registered Office;
6 rue Alain Bombard, 44800 Saint-Herblain (France)
Nantes Trade and Companies Registry (R.C.S.)
No. 422 497 560
VALNEVA SE
Campus Bio-Ouest | 6, Rue Alain Bombard
44800 Saint-Herblain, France
Valneva Reports Nine-Month 2024 Financial Results and Provides Corporate Updates
Nine-Month Key Financial Highlights
•Total revenues of €116.6 million, including product sales of €112.5 million
•Net Profit of €24.7 million, including proceeds from the Priority Review Voucher (PRV)1 sale
◦Operating profit of €34.2 million compared to an operating loss of €57.2 million in the first nine-months of 2023
•Cash position of €156.3 million
◦Includes €61.2 million in gross proceeds from recent private placement2
◦Lower cash burn expected in the second half of 2024 as cost contributions to the agreed R&D budget for partnered Lyme disease program were completed in the second quarter of the year
Full-year 2024 Financial Guidance Narrowed
•Expected total product sales according to guidance between €160 million to €170 million and currently anticipated total revenues between €170 million and €180 million
•Expected R&D investments between €65 million and €75 million
•Expected Other income between €100 million and €110 million, including €95 million from the PRV sale
•Launch of the world’s first chikungunya vaccine in Canada and Europe underway; Further potential approvals expected in Brazil (Q4 2024) and the UK (Q1 2025)
Strategic Pipeline Expansion, Strong Clinical and Regulatory Execution
•Secured exclusive worldwide license for S4V2 Shigella vaccine candidate, adding an attractive Phase 2 clinical asset to Valneva’s R&D pipeline3 - recently granted FDA Fast Track4
•Submitted key label extension(s) for IXCHIQ® in Europe and Canada5
1 Valneva Announces Sale of Priority Review Voucher for $103 Million - Valneva
2 Valneva Announces the Success of its Private Placement Raising approximately €60 Million - Valneva
3 Valneva and LimmaTech Enter into a Strategic Partnership to Accelerate the Development of the World’s Most Clinically Advanced Tetravalent Shigella Vaccine Candidate - Valneva
4 Valneva and LimmaTech Awarded FDA Fast Track Designation for Tetravalent Shigella Vaccine Candidate S4V - Valneva
5 Valneva Submits Label Extension Applications for its Chikungunya Vaccine, IXCHIQ®, to EMA and Health Canada - Valneva
November 7, 2024 VALNEVA SE
•Published IXCHIQ® two-year antibody persistence and safety data in the Lancet Infectious Diseases6 further demonstrating the vaccine’s highly differentiated immunological profile
•Awarded new $41.3 million CEPI grant7 to contribute significantly to IXCHIQ® Phase 4 costs and other studies supporting broader access to the vaccine
•Pfizer completed primary vaccination (three doses) in Phase 3 VALOR Lyme disease trial8
•Advancing Phase 1 clinical trial for second-generation Zika vaccine candidate toward expected data readout and further decision on potential development path in 20259
Financial Information
(Unaudited results, consolidated per IFRS)
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€ in million | Nine months ended September 30, |
| 2024 | 2023 |
Total Revenues | 116.6 | 111.8 |
Product Sales | 112.5 | 106.1 |
Net profit/(loss) | 24.7 | -69.3 |
Adjusted EBITDA10 | 48.6 | -46.0 |
Cash | 156.3 | 171.3 |
Saint-Herblain (France), November 7, 2024 – Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company, today reported consolidated financial results for the first nine months of the year, ended September 30, 2024. The condensed consolidated interim financial results are available on the Company’s website (Financial Reports – Valneva).
Valneva will provide a live webcast of its nine-month 2024 results conference call beginning at 3 p.m. CET / 9 a.m. ET today. This webcast will also be available on the Company’s website. Please refer to this link: https://edge.media-server.com/mmc/p/6wzgxkji.
Peter Bühler, Valneva’s Chief Financial Officer, commented, “Our objective is to become sustainably profitable in 2027, based on potential milestone and commercial revenues from our Lyme disease vaccine candidate, if approved. We remain focused on growing sales of our travel vaccines and believe we are sufficiently capitalized, while maintaining the flexibility to continue investing in the future development of the Company by leveraging our proven R&D capabilities. As we approach the conclusion of the Phase 3 Lyme disease trial at the end of next year, we believe we are entering a pivotal time in Valneva’s evolution.”
6 Antibody persistence and safety of a live-attenuated chikungunya virus vaccine up to 2 years after single-dose administration in adults in the USA: a single-arm, multicentre, phase 3b study - The Lancet Infectious Diseases
7 CEPI Expands Partnership with Valneva with a $41.3 Million Grant to Support Broader Access to the World’s First Chikungunya Vaccine - Valneva
8 Phase 3 VALOR Lyme Disease Trial: Valneva and Pfizer Announce Primary Vaccination Series Completion - Valneva
9 Valneva Initiates Phase 1 Trial of Second-Generation Zika Vaccine Candidate - Valneva
10 For additional information on Adjusted EBITDA, please refer to the “Non-IFRS Financial Measures” section at the end of the PR
Commercial Portfolio
Valneva’s commercial portfolio is composed of three travel vaccines, IXIARO®/JESPECT®, DUKORAL® and recently launched IXCHIQ®. The Company also distributes certain third-party products in countries where it operates its own marketing and sales infrastructure.
Valneva’s sales in the first nine months of 2024 were €112.5 million compared to €106.1 million (€100.4 million excluding final COVID-19 vaccine sales) in the first nine months of 2023.
JAPANESE ENCEPHALITIS VACCINE IXIARO®/JESPECT®
In the first nine months of 2024, IXIARO®/JESPECT® sales increased by 31% to €66.0 million compared to €50.3 million in the first nine months of 2023. Sales to both travelers and the U.S. military showed double digit growth compared to the first nine months of 2023.
Valneva has been supplying additional doses of IXIARO® to the U.S. Department of Defense (DoD) under the current contract, signed in September 202311, which allowed the DoD to purchase additional doses during the following twelve months. Valneva expects to receive new orders in 2025.
CHOLERA / ETEC12-DIARRHEA VACCINE DUKORAL®
In the first nine months of 2024, DUKORAL® sales were €22.3 million compared to €21.1 million in the first nine months of 2023. At the end of June, DUKORAL® sales remained below prior year but sales in the third quarter grew 85% year-over-year, as marketing investments resumed in the third quarter following successful regulatory inspection of Valneva’s new manufacturing site in Sweden.
CHIKUNGUNYA VACCINE IXCHIQ®
IXCHIQ® is the world’s first and only licensed chikungunya vaccine available to address this significant unmet medical need. The vaccine is now approved in the U.S.13, Europe14, and Canada15 for the prevention of disease caused by the chikungunya virus in individuals 18 years of age and older. The U.S. launch is underway while first sales in Canada and Europe are anticipated in the fourth quarter of 2024.
Following adoption of the U.S. Advisory Committee on Immunization Practices (ACIP)’s recommendations by the U.S. Centers for Disease Control and Prevention (CDC)16 at the beginning of March 2024, Valneva recognized initial sales of €1.8 million in the first nine months of 2024. Valneva is focused on growing IXCHIQ® sales in the U.S., particularly among older adults (6
11 Valneva Announces New IXIARO® Supply Contract with the U.S. Government Worth a Minimum of $32 Million - Valneva
12 Indications differ by country - Please refer to Product / Prescribing Information (PI) / Medication Guide approved in your respective countries for complete information, incl. dosing, safety and age groups in which this vaccine is licensed, ETEC = Enterotoxigenic Escherichia coli (E. Coli) bacterium.
13 Valneva Announces U.S. FDA Approval of World’s First Chikungunya Vaccine, IXCHIQ® - Valneva
14 Valneva Receives Marketing Authorization in Europe for the World’s First Chikungunya Vaccine, IXCHIQ® - Valneva
15 Valneva Announces Health Canada Approval of the World’s First Chikungunya Vaccine, IXCHIQ® - Valneva
16 ACIP Vaccine Recommendations and Schedules | CDC
5+ years old) who are at high risk for severe chikungunya infection and for whom ACIP recommends vaccination for certain travelers.
Valneva remains confident in the long-term prospects for IXCHIQ®, and while U.S. sales have started slow, several factors are expected to drive future growth, including expanded access to the retail channel via publication of the ACIP recommendations in the Morbidity and Mortality Weekly Report (MMWR)17 and anticipated label expansion(s). The U.S. Defense Health Agency – Immunization Healthcare Division (DHA-IHD) also recently published chikungunya and vaccines guidance, which authorizes IXCHIQ® as a Department of Defense CHIKV countermeasure. Key launch metrics that are expected to enable future sales growth, including stocking and re-stocking across all sales channels, active customer accounts, as well as reimbursement for IXCHIQ® by commercial and MediCare insurance plans, continue to track in line with expectations, providing confidence in future sales growth.
The Company plans to review its mid-term IXCHIQ® sales guidance in the coming months, taking into account sales trends in the U.S., early insights into sales performance in Canada and first European Union (EU) countries, as well as demand from existing and potential future Low- and Middle-Income Countries (LMIC) partners.
Regulatory review is ongoing in Brazil and the UK and the Company recently filed18 and is preparing further filings for label extension to adolescents in markets where IXCHIQ® is approved, including key antibody persistence data to further establish IXCHIQ® as a differentiated brand. Phase 3 antibody persistence results two years after vaccination with a single dose were recently published in The Lancet19 showing that IXCHIQ®’s robust immune response was sustained by 97% of participants and was equally durable in younger and older adults. Valneva now expects to report three-year persistence data later this year. These important label updates, combined with anticipated ex-U.S. and endemic product launches are expected to significantly expand access of IXCHIQ® and contribute to its future revenues.
Additionally, Valneva recently expanded its partnership with CEPI20 to support broader access to the vaccine in LMICs, post-marketing trials and potential label extensions in children, adolescents and pregnant women. CEPI will provide Valneva up to $41.3 million of additional funding over the next five years, with support from the EU’s Horizon Europe program.
THIRD-PARTY DISTRIBUTION
Valneva distributes certain third-party vaccines in countries where it operates its own marketing and sales infrastructure. During the first nine months of 2024, third-party sales decreased by 23% to €22.5 million compared to €29.1 million in the first nine months of 2023 as a result of external supply constraints in the first half of the year.
17 The MMWR Recommendations and Reports contain in-depth articles that relay policy statements for prevention and treatment on all areas in CDC’s scope of responsibility (e.g., recommendations from the Advisory Committee on Immunization Practices).
18 Valneva Submits Label Extension Applications for its Chikungunya Vaccine, IXCHIQ®, to EMA and Health Canada - Valneva
19 Antibody persistence and safety of a live-attenuated chikungunya virus vaccine up to 2 years after single-dose administration in adults in the USA: a single-arm, multicentre, phase 3b study - The Lancet Infectious Diseases
20 CEPI Expands Partnership with Valneva with a $41.3 Million Grant to Support Broader Access to the World’s First Chikungunya Vaccine - Valneva
Valneva continues to expect a 20 to 30% reduction in third-party sales in 2024 and to gradually wind down third-party sales to less than 5% of overall product sales by 2026/2027, resulting in overall gross margin improvement.
Clinical Vaccine Candidates
LYME DISEASE VACCINE CANDIDATE – VLA15
Phase 3 primary vaccination completed
VLA15 is the Lyme disease vaccine candidate which has advanced the furthest along the clinical development timeline, with two Phase 3 trials in progress. It leverages an established mechanism of action against Lyme borreliosis infection by targeting the six most prevalent serotypes of the Borrelia outer surface protein A (OspA).
Pfizer and Valneva are currently executing the Phase 3 field efficacy study for VLA15 called VALOR (Vaccine Against Lyme for Outdoor Recreationists). Enrollment in the trial was completed in December 2023 and primary vaccination series was completed in July 202421. Participants will be monitored for the occurrence of Lyme disease cases until the end of the Lyme disease season in 2025.
Pfizer aims to submit a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) and Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) in 2026, subject to positive Phase 3 data. If approved and commercialized, Valneva will be eligible to receive $143 million in initial sales milestones from Pfizer, plus ongoing sales royalties ranging from 14% to 22% and an additional $100 million in cumulative sales milestones.
Based on the agreement with Pfizer, Valneva’s expected cost contributions for the Lyme disease program were completed in the second quarter of 2024, contributing to a substantially lower expected cash burn in the second half of 2024.
SHIGELLA VACCINE CANDIDATE – S4V2
The World’s most clinically advanced tetravalent Shigella vaccine candidate
In August 2024, Valneva entered into a strategic partnership and exclusive licensing agreement with LimmaTech Biologics AG for the development, manufacturing and commercialization of Shigella4V2 (S4V2), a tetravalent bioconjugate vaccine candidate against shigellosis22.
The U.S. Food and Drug Administration (FDA) recently granted Fast Track designation to S4V2, recognizing its potential to address a serious condition and fill an unmet medical need23.
Shigellosis, caused by Shigella bacteria, is the second leading cause of fatal diarrheal disease worldwide. It is estimated that up to 165 million cases of disease and an estimated 600,000 deaths are attributed to Shigella each year24, particularly among children in LMICs. No approved Shigella vaccine is currently available and the development of Shigella vaccines has been identifie
21 Phase 3 VALOR Lyme Disease Trial: Valneva and Pfizer Announce Primary Vaccination Series Completion - Valneva
22 LimmaTech Biologics AG
23 Valneva and LimmaTech Awarded FDA Fast Track Designation for Tetravalent Shigella Vaccine Candidate S4V - Valneva
24 Shigellosis | CDC Yellow Book 2024
d as a priority by the World Health Organization (WHO)25. Shigellosis also affects international travelers from high-income countries and deployed military personnel in endemic regions. The global market for a vaccine against Shigella is estimated to exceed $500 million annually26.
The anticipated development path follows a staggered and risk-mitigated strategy, allowing for efficient capital allocation. LimmaTech will conduct a Phase 2 Controlled Human Infection Model study (CHIM) in the U.S. and a Phase 2 pediatric study in LMICs expected to begin in the second half of 2024. Valneva will assume all further development, including CMC (chemistry, manufacturing and controls) and regulatory activities, and be responsible for its commercialization worldwide if approved.
Under the terms of the agreement, LimmaTech received an upfront payment of €10 million and is eligible to receive additional regulatory, development and sales-based milestone payments of up to €40 million as well as low double-digit royalties on sales.
ZIKA VACCINE CANDIDATE – VLA1601
Phase 1 ongoing with second-generation vaccine candidate
VLA1601 is a second-generation adjuvanted inactivated vaccine candidate against the mosquito-borne disease caused by the Zika virus (ZIKV). In March 2024, Valneva initiated a Phase 1 clinical trial to investigate the safety and immunogenicity of VLA160127. The randomized, placebo-controlled, Phase 1 trial, VLA1601-102, is planned to enroll approximately 150 participants aged 18 to 49 years in the United States. Participants will receive a low, medium or high dose of VLA1601. In addition, the low dose of VLA1601 will be evaluated with an additional adjuvant. Sentinel recruitment and vaccinations have been completed and the start of the randomized phase is imminent. Data from the trial are expected in the first half of 2025.
Zika disease outbreaks have been reported in tropical Africa, Southeast Asia, the Pacific Islands, and, since 2015, in the Americas. Zika virus transmission persists in several countries in the Americas and in other endemic regions. To date, a total of 89 countries and territories have reported evidence of mosquito transmitted Zika virus infection28; however, surveillance remains limited globally. There are no preventive vaccines or effective treatments available and, as such, Zika remains a public health threat and is included in the FDA’s Tropical Disease Priority Review Voucher Program29.
A vaccine against ZIKV could be a valuable addition to Valneva’s portfolio against mosquito-borne diseases, which already includes IXCHIQ® and IXIARO®.
25 Immunization, Vaccines and Biologicals (who.int)
26 LEK analysis
27 Valneva Initiates Phase 1 Trial of Second-Generation Zika Vaccine Candidate - Valneva
28 Zika virus disease (who.int)
29 Tropical Disease Priority Review Voucher Program | FDA
Nine Months 2024 Financial Review
(Unaudited, consolidated under IFRS)
Revenues
Valneva’s total revenues were €116.6 million in the nine months ended September 30, 2024 compared to €111.8 million in the nine months ended September 30, 2023.
Valneva’s total product sales reached €112.5 million in the first nine months of 2024 compared to €106.1 million in the same period of 2023. The impact of currency fluctuations of €0.1 million was minimal.
Excluding COVID-19 vaccine sales in the nine months ended September 30, 2023, travel vaccine sales showed a growth of €12.1 million or 12% year-over-year.
IXIARO®/JESPECT® sales were €66.0 million in the first nine months of 2024 compared to €50.3 million in the nine months ended September 30, 2023. The 31% increase reflects double digit growth in sales to both travelers (11%) and the US military. The impact of foreign currency movements in IXIARO®/JESPECT® sales was negligible.
DUKORAL® sales were €22.3 million in the first nine months of 2024 compared to €21.1 million in the comparative period of 2023. This 6% increase was due to marketing investments resuming in the third quarter of 2024 following successful regulatory inspection of Valneva’s new manufacturing facility in Sweden. Foreign currency fluctuations had an immaterial impact on DUKORAL® sales.
Following adoption of the U.S. ACIP’s recommendations by the U.S. CDC at the beginning of March 2024, Valneva recognized initial sales for IXCHIQ® of €1.8 million in the first nine months of 2024.
Third Party product sales were €22.5 million in the first nine months of 2024 compared to €29.1 million in the same period of 2023. This 23% decrease was mainly driven by lower sales of Rabipur®/RabAvert® and Encepur®, under the distribution agreement with Bavarian Nordic, as a result of external supply constraints in the first half of the year.
Other revenues, including revenues from collaborations, licensing and services amounted to €4.2 million in the first nine months of 2024 compared to €5.7 million in the same period of 2023. The reduction mainly resulted from lower revenue recognition related to the R&D collaboration activities for chikungunya with Instituto Butantan.
Operating Result and adjusted EBITDA
Costs of goods and services sold (COGS) were €71.3 million in the nine months ended September 30, 2024. The gross margin on commercial product sales, excluding IXCHIQ®, amounted to 48.6% compared to 43.7% in the nine months ended September 30, 2023. COGS of €27.2 million related to IXIARO® product sales, yielding a product gross margin of 58.8%. COGS of €14.5 million related to DUKORAL® product sales, yielding a product gross margin of 34.8%. Product gross margins continued recovering during the third quarter of 2024 as the supply shortages during the first half were resolved. Of the remaining COGS in the first nine
months of 2024, €15.2 million related to the third-party products distribution business, €4.6 million to IXCHIQ®, €3.6 million to idle capacity costs and €6.3 million to cost of services. In the first nine months of 2023, overall COGS were €74.8 million, of which €67.6 million related to cost of goods and €7.2 million related to cost of services.
Research and development expenses amounted to €48.6 million in the first nine months of 2024, compared to €42.2 million in the first nine months of 2023. This increase was mainly driven by higher costs related to the ongoing transfer of operations into the new Almeida manufacturing facility. Marketing and distribution expenses in the first nine months of 2024 amounted to €35.7 million compared to €33.9 million in the first nine months of 2023. The increase is mainly related to €16.2 million of expenses associated with launch activities for IXCHIQ® (first nine months of 2023: €13.8 million). In the first nine months of 2024, general and administrative expenses reduced to €32.6 million after €35.1 million in the same period of 2023. The largest expense categories were employee-related expenses of €15.0 million and consulting and other services of €13.1 million.
During the first nine months of 2024, a net gain of €90.8 million from the sale of the PRV was recorded. The gross proceeds of $103 million were reduced by transaction costs as well as contractual payment obligations related to the sale of the PRV.
Other income, net of other expenses decreased to €14.9 million in the nine months ended September 30, 2024 from €17.0 million in the nine months ended September 30, 2023. In the first nine months of 2024 Valneva recorded €6.2 million income from the recently awarded CEPI grant. The first nine months of 2023 included income of €10.3 million awarded by Scottish Enterprise (SE) for non-COVID-19 vaccine development (IXCHIQ® and IXIARO®).
Valneva recorded an operating income of €34.2 million in the first nine months of 2024 compared to an operating loss of €57.2 million in the comparative period of 2023. The increase was mainly the result of the PRV sale.
Adjusted EBITDA (as defined below) profit in the first nine months of 2024 was €48.6 million, whereas in the first nine months of 2023 an adjusted EBITDA loss of €46.0 million was recorded.
Net Result
In the first nine months of 2024, Valneva generated a net profit of €24.7 million, mainly resulting from the sale of the PRV in February 2024. This compared to a net loss of €69.3 million in the first nine months of 2023.
Finance expense and currency effects in the first nine months of 2024 resulted in a net finance expense of €13.4 million, compared to a net finance expense of €13.2 million in the first nine months of 2023. This increase was mainly due to €5.2 million higher interest expenses on loans resulting from the amendment of the Deerfield Management Company and OrbiMed (D&O) loan facility. Additionally foreign exchange profits of €3.0 million were recorded in the first nine months of 2024 compared to losses of €1.4 million observed in the first nine months of 2023, primarily related to the development of the USD and GBP exchange rates to the EUR.
Cash Flow and Liquidity
Net cash used in operating activities amounted to €76.7 million in the first nine months of 2024 compared to €136.8 million of cash used in operating activities in the same period of 2023. Cash outflows in the first nine months of 2024 were largely derived from the operating loss for the period (excluding gains from PRV sale) amounting to €66.1 million and from working capital in the amount of €35.1 million which includes Valneva’s final agreed-upon payments to the Lyme disease clinical program. In the first nine months of 2023, changes in working capital were higher, mainly related to higher payments to Pfizer in conjunction with the Lyme disease program, reducing the refund liability.
Cash inflows from investing activities amounted to €72.2 million in the first nine months of 2024 compared to cash outflows of €4.3 million in the first nine months of 2023. Both years included outflows from construction activities across production sites in Scotland and Sweden and, in addition, 2024 included outflows from the upfront payment to LimmaTech Biologics AG recorded as purchase of an intangible asset. The sale of the PRV positively impacted 2024 by €90.8 million.
Net cash generated in financing activities increased to €35.3 million in the first nine months of 2024 from €26.1 million in the first nine months of 2023. This increase was primarily due to €57.5 million net proceeds from the recent private placement completed in the third quarter of 2024, while the first nine months of 2023 included proceeds from the increase of the loan facility provided by Deerfield Management Company and OrbiMed.
Cash and cash equivalents were €156.3 million as at September 30, 2024, compared to €126.1 million at December 31, 2023.
Non-IFRS Financial Measures
Management uses and presents IFRS results as well as the non-IFRS measure of Adjusted EBITDA to evaluate and communicate its performance. While non-IFRS measures should not be construed as alternatives to IFRS measures, management believes non-IFRS measures are useful to further understand Valneva’s current performance, performance trends, and financial condition.
Adjusted EBITDA is a common supplemental measure of performance used by investors and financial analysts. Management believes this measure provide additional analytical tools. Adjusted EBITDA is defined as net profit / (loss) for the period before income tax, finance income/expense, foreign exchange (gain)/loss, amortization, depreciation, and impairment (excluding impairment loss of disposal).
A reconciliation of Adjusted EBITDA net profit / (loss), which is the most directly comparable IFRS measure, is set forth below:
| | | | | | | | |
€ in million | Nine months ended September 30, |
(unaudited results, consolidated per IFRS) | 2024 | 2023 |
Net profit / (loss) | 24.7 | -69.3 |
Add: |
|
|
Income tax (benefits)/expense | -3.9 | -1.1 |
Total finance income | -1.3 | -0.7 |
Total finance expense | 17.7 | 12.5 |
Foreign currency (gain)/loss - net | -3.0 | 1.4 |
Amortization | 3.7 | 4.7 |
Depreciation | 10.7 | 8.4 |
Impairment, excluding impairment loss of disposal | 0.0 | -1.9 |
Adjusted EBITDA | 48.6 | -46.0 |
About Valneva SE
We are a specialty vaccine company that develops, manufactures, and commercializes prophylactic vaccines for infectious diseases addressing unmet medical needs. We take a highly specialized and targeted approach, applying our deep expertise across multiple vaccine modalities, focused on providing either first-, best- or only-in-class vaccine solutions.
We have a strong track record, having advanced multiple vaccines from early R&D to approvals, and currently market three proprietary travel vaccines, including the world’s first and only chikungunya vaccine, as well as certain third-party vaccines.
Revenues from our growing commercial business help fuel the continued advancement of our vaccine pipeline. This includes the only Lyme disease vaccine candidate in advanced clinical development, which is partnered with Pfizer, the world’s most clinically advanced Shigella vaccine candidate, as well as vaccine candidates against the Zika virus and other global public health threats. More information is available at www.valneva.com.
| | | | | | | | | | | |
Valneva Investor and Media Contacts Laetitia Bachelot-Fontaine VP, Global Communications and European Investor Relations M +33 (0)6 4516 7099 investors@valneva.com |
Joshua Drumm, Ph.D. VP, Global Investor Relations M +001 917 815 4520 joshua.drumm@valneva.com |
| |
Forward-Looking Statements
This press release contains certain forward-looking statements relating to the business of Valneva, including with respect to financial results for 2024; mid-term revenue and cash outlook; the progress, timing, results and completion of research, development and clinical trials for product candidates; regulatory approval of product candidates and requested label extensions; and review of existing products. In addition, even if the actual results or development of Valneva are consistent with the forward-looking statements contained in this press release, those results or developments of Valneva may not be sustained in the future. In some cases, you can identify forward-looking statements by words such as “could,” “should,” “may,” “expects,” “anticipates,” “believes,” “intends,” “estimates,” “aims,” “targets,” or similar words. These forward-looking statements are based largely on the current expectations of Valneva as of the date of this press release and are subject to a number of known and unknown risks and uncertainties and other factors that may cause actual results, performance or achievements to be materially different from any future results, performance or achievement expressed or implied by these forward-looking statements. In particular, the expectations of Valneva could be affected by, among other things, uncertainties and delays involved in the development and manufacture of vaccines, unexpected clinical trial results, unexpected regulatory actions or delays, competition in general, currency fluctuations, the impact of the global and European credit crisis, and the ability to obtain or maintain patent or other proprietary intellectual property protection. Success in preclinical studies or earlier clinical trials may not be indicative of results in future clinical trials. In light of these risks and uncertainties, there can be no assurance that the forward-looking statements made in this press release will in fact be realized. Valneva is providing this information as of the date of this press release and disclaims any intention or obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.
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v3.24.3
Unaudited Interim Condensed Consolidated Statements of Income (Loss) - EUR (€) € in Thousands |
9 Months Ended |
Sep. 30, 2024 |
Sep. 30, 2023 |
Profit or loss [abstract] |
|
|
Product sales |
€ 112,475
|
€ 106,130
|
Other revenues |
4,162
|
5,684
|
REVENUES |
116,637
|
111,814
|
Cost of goods and services |
(71,306)
|
(74,810)
|
Research and development expenses |
(48,567)
|
(42,220)
|
Marketing and distribution expenses |
(35,718)
|
(33,919)
|
General and administrative expenses |
(32,554)
|
(35,066)
|
Gain from sale of Priority Review Voucher, net |
90,833
|
0
|
Other income and expenses, net |
14,890
|
17,020
|
OPERATING PROFIT/(LOSS) |
34,214
|
(57,180)
|
Finance income |
1,316
|
724
|
Finance expenses |
(17,713)
|
(12,477)
|
Foreign exchange gain/(loss), net |
3,045
|
(1,441)
|
PROFIT/(LOSS) BEFORE INCOME TAX |
20,862
|
(70,374)
|
Income tax benefit/(expense) |
3,878
|
1,103
|
PROFIT/(LOSS) FOR THE PERIOD |
€ 24,740
|
€ (69,271)
|
Earnings/(losses) per share for profit/(loss) for the period attributable to the equity holders of the Company (expressed in € per share) |
|
|
Basic earnings (losses) per share for profit/(loss) for the period attributable to the equity holders of the Company (in euro per share) |
€ 0.18
|
€ (0.50)
|
Diluted earnings (losses) per share for profit/(loss) for the period attributable to the equity holders of the Company (in euro per share) |
€ 0.17
|
€ (0.50)
|
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v3.24.3
Unaudited Interim Condensed Consolidated Statement of Financial Position - EUR (€) € in Thousands |
Sep. 30, 2024 |
Dec. 31, 2023 |
ASSETS |
|
|
Non-current assets |
€ 213,000
|
€ 197,238
|
Intangible assets |
33,478
|
25,567
|
Right of use assets |
18,653
|
20,392
|
Property, plant and equipment |
141,647
|
136,198
|
Deferred tax assets |
11,667
|
6,592
|
Other non-current assets |
7,555
|
8,490
|
Current assets |
303,614
|
262,824
|
Inventories |
57,829
|
44,466
|
Trade receivables |
30,359
|
41,645
|
Other current assets |
59,091
|
50,633
|
Cash and cash equivalents |
156,335
|
126,080
|
TOTAL ASSETS |
516,614
|
460,062
|
EQUITY |
|
|
Share capital |
24,342
|
20,837
|
Share premium |
647,640
|
594,003
|
Other reserves |
72,430
|
65,088
|
Retained earnings/(Accumulated deficit) |
(551,682)
|
(450,253)
|
Profit/(Loss) for the period |
24,740
|
(101,429)
|
TOTAL EQUITY |
217,469
|
128,247
|
LIABILITIES |
|
|
Non-current liabilities |
189,989
|
172,952
|
Borrowings |
153,126
|
132,768
|
Lease liabilities |
26,015
|
29,090
|
Refund liabilities |
6,443
|
6,303
|
Provisions |
562
|
1,074
|
Deferred tax liabilities |
3,791
|
3,638
|
Other liabilities |
52
|
79
|
Current liabilities |
109,156
|
158,863
|
Borrowings |
19,452
|
44,079
|
Trade payables and accruals |
42,897
|
44,303
|
Income tax liability |
266
|
632
|
Tax and Employee-related liabilities |
18,319
|
16,209
|
Lease liabilities |
2,655
|
2,879
|
Contract liabilities |
956
|
5,697
|
Refund liabilities |
17,095
|
33,637
|
Provisions |
7,290
|
10,835
|
Other liabilities |
226
|
592
|
TOTAL LIABILITIES |
299,145
|
331,815
|
TOTAL EQUITY AND LIABILITIES |
€ 516,614
|
€ 460,062
|
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v3.24.3
Unaudited Interim Condensed Consolidated Statement of Cash Flows - EUR (€) € in Thousands |
9 Months Ended |
Sep. 30, 2024 |
Sep. 30, 2023 |
CASH FLOWS FROM OPERATING ACTIVITIES |
|
|
Profit/(Loss) for the period |
€ 24,740
|
€ (69,271)
|
Gain from sale of Priority Review Voucher, net |
(90,833)
|
0
|
Adjustments for non-cash transactions |
25,672
|
26,867
|
Changes in non-current operating assets and liabilities |
311
|
(181)
|
Changes in working capital |
(35,075)
|
(93,335)
|
Cash generated/(used) in operations |
(75,186)
|
(135,920)
|
Income tax paid |
(1,558)
|
(913)
|
NET CASH GENERATED FROM/(USED IN) OPERATING ACTIVITIES |
(76,744)
|
(136,833)
|
CASH FLOWS FROM INVESTING ACTIVITIES |
|
|
Purchases of property, plant and equipment |
(10,006)
|
(8,354)
|
Proceeds from sale of property, plant and equipment |
165
|
43
|
Purchases of intangible assets |
(10,079)
|
(39)
|
Proceeds from assets classified as held for sale |
0
|
3,358
|
Proceeds from sale of Priority Review Voucher |
90,833
|
0
|
Interest received |
1,316
|
724
|
NET CASH GENERATED FROM/(USED IN) INVESTING ACTIVITIES |
72,228
|
(4,269)
|
CASH FLOWS FROM FINANCING ACTIVITIES |
|
|
Proceeds/(payments) from issuance of common stock, net of costs of equity transactions |
57,460
|
(240)
|
Proceeds from borrowings, net of transaction costs |
(944)
|
39,683
|
Repayment of borrowings |
(3,723)
|
(2,097)
|
Payment of lease liabilities |
(2,788)
|
(2,444)
|
Interest paid |
(14,733)
|
(8,764)
|
NET CASH GENERATED FROM/(USED IN) FINANCING ACTIVITIES |
35,272
|
26,137
|
NET CHANGE IN CASH AND CASH EQUIVALENTS |
30,757
|
(114,964)
|
Cash and cash equivalents at beginning of the year |
126,080
|
286,532
|
Exchange gains/(losses) on cash |
(502)
|
(315)
|
CASH AND CASH EQUIVALENTS AT END OF THE PERIOD |
€ 156,335
|
€ 171,253
|
X |
- DefinitionThe cash flows from (used in) financing activities, which are activities that result in changes in the size and composition of the contributed equity and borrowings of the entity, from continuing and discontinued operations.
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v3.24.3
Unaudited Interim Condensed Consolidated Statement of Changes in Equity - EUR (€) € in Thousands |
Total |
Share capital |
Share premium |
Other reserves |
Retained earnings/ (Accumulated deficit) |
Profit/(loss) for the period |
Equity, beginning balance at Dec. 31, 2022 |
€ 219,797
|
€ 20,755
|
€ 594,043
|
€ 55,252
|
€ (306,974)
|
€ (143,279)
|
Total comprehensive income/(loss) |
(67,602)
|
|
|
1,669
|
|
(69,271)
|
Income appropriation |
0
|
|
|
|
(143,279)
|
143,279
|
Share-based compensation expense: |
|
|
|
|
|
|
Value of services |
5,284
|
|
|
5,284
|
|
|
Exercises |
42
|
82
|
(39)
|
|
|
|
Equity, ending balance at Sep. 30, 2023 |
157,521
|
20,837
|
594,003
|
62,205
|
(450,253)
|
(69,271)
|
Equity, beginning balance at Dec. 31, 2023 |
128,247
|
20,837
|
594,003
|
65,088
|
(450,253)
|
(101,429)
|
Total comprehensive income/(loss) |
25,342
|
|
|
602
|
|
24,740
|
Income appropriation |
0
|
|
|
|
(101,429)
|
101,429
|
Share-based compensation expense: |
|
|
|
|
|
|
Value of services |
6,740
|
|
|
6,740
|
|
|
Exercises |
0
|
55
|
(55)
|
|
|
|
Capital Increase |
61,180
|
3,450
|
57,730
|
|
|
|
Cost of equity transaction, net of tax |
(4,039)
|
|
(4,039)
|
|
|
|
Equity, ending balance at Sep. 30, 2024 |
€ 217,469
|
€ 24,342
|
€ 647,640
|
€ 72,430
|
€ (551,682)
|
€ 24,740
|
X |
- DefinitionThe amount of change in equity resulting from transactions and other events, other than those changes resulting from transactions with owners in their capacity as owners.
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