RNS Number:4561T                                                                          
AstraZeneca PLC
19 December 2003

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 18 December 2003, it purchased for
cancellation 200,000 ordinary shares of AstraZeneca PLC at a price of 2585 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,692,623,745.


G H R Musker
Company Secretary
19 December 2003


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