RNS Number:2269D
Cambridge Antibody Tech Group PLC
18 May 2006


                   NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Name of company



Cambridge Antibody Technology Group plc



2. Name of shareholder having a major interest



The Goldman Sachs Group Inc.



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

Goldman Sachs Securities (Nominees) Limited      non beneficial
The Depositary Trust Company, New York           non beneficial
Goldman Sachs Securities (Nominees) Limited          beneficial
The Depositary Trust Company, New York               beneficial
Goldman Sachs International (CREST a/c CREPTEMP)     beneficial
Goldman Sachs JBWere Managed Funds Limited           beneficial



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

Goldman Sachs Securities (Nominees) Limited             873,435
The Depositary Trust Company, New York                  475,065
Goldman Sachs Securities (Nominees) Limited               1,400
The Depositary Trust Company, New York                      200
Goldman Sachs International (CREST a/c CREPTEMP)        871,289
Goldman Sachs JBWere Managed Funds Limited               87,360



5. Number of shares / amount of stock acquired



not disclosed



6. Percentage of issued class



not known



7. Number of shares / amount of stock disposed



None



8. Percentage of issued class



N/A



9. Class of security



Ordinary 10 pence shares



10. Date of transaction



15 May 2006



11. Date company informed



18 May 2006



12. Total holding following this notification



2,308,749



13. Total percentage holding of issued class following this notification



4.34%



14. Any additional information



None



15. Name of contact and telephone number for queries



Justin Hoskins 01223 898589



16. Name and signature of authorised company official responsible for making
this notification



Justin Hoskins, Company Secretary



Date of notification



18 May 2006



The FSA does not give any express or implied warranty as to the accuracy of this
document or material and does not accept any liability for error or omission.
The FSA is not liable for any damages (including, without limitation, damages
for loss of business or loss of profits) arising in contract, tort or otherwise
from the use of or inability to use this document, or any material contained in
it, or from any action or decision taken as a result of using this document or
any such material.




                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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