RNS Number:8641B
Cambridge Antibody Tech Group PLC
30 September 2002

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
John Aston


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
As in 2 above


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
As in 2 above


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)
As in 2 above


6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Exercise of options under Unapproved Executive Scheme


7) Number of shares/amount of
stock acquired
5,000


8) Percentage of issued class
0.014%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10p shares


12) Price per share
#3.00


13) Date of transaction
30 September 2002


14) Date company informed
30 September 2002


15) Total holding following this notification
27,857


16) Total percentage holding of issued class following this notification
0.077%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 30 September 2002





                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

1) Name of company
Cambridge Antibody Technology


2) Name of director
Peter Chambre


3) Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18 or in respect of a
non-beneficial interest
Spouse


4) Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them (if notified)
Sarah Frances Elizabeth Chambre (spouse)


5) Please state whether notification relates to a person(s) connected
with the Director named in 2 above and identify the connected person(s)
Spouse


6) Please state the nature of the transaction. For PEP transactions
please indicate whether general/single co PEP and if discretionary/non
discretionary
Market purchase of 6529 shares


7) Number of shares/amount of
stock acquired
6529


8) Percentage of issued class
0.018%


9) Number of shares/amount
of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10p shares


12) Price per share
#4.59


13) Date of transaction
30 September 2002


14) Date company informed
30 September 2002


15) Total holding following this notification
9529


16) Total percentage holding of issued class following this notification
0.026%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01763 263233


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett Company Secretary

Date of Notification 30 September 2002


                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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