RNS Number:0265F
Cambridge Antibody Tech Group PLC
12 December 2002

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

 1. Name of company

    Cambridge Antibody Technology

    2) Name of director

    John Aston

    3) Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
    non-beneficial interest or in the case of an individual holder if it is a
    holding of that person's spouse or children under the age of 18 or in
    respect of a non-beneficial interest

    As in 2 above

    4) Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

    Computershare Trustees Limited

    5) Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

    As in 2 above

    6) Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

    Allocation of partnership and matching shares under Inland Revenue Approved
    Share Incentive Plan

    7) Number of shares/amount of
    stock acquired

    610 ( consisting of 305 partnership shares and 305 matching shares)

    8) Percentage of issued class

    0.0017%

    9) Number of shares/amount
    of stock disposed

    Nil

    10) Percentage of issued class

    N/A

    11) Class of security

    Ordinary 10 Pence

    12) Price per share

    #4.91

    13) Date of transaction

    11 December 2002

    14) Date company informed

    11 December 2002

    15) Total holding following this notification

    28,798

    16) Total percentage holding of issued class following this notification

    0.079%

    If a director has been granted options by the company please complete the
    following boxes

    17) Date of grant



    18) Period during which or date on which exercisable



    19) Total amount paid (if any) for grant of the option



    20) Description of shares or debentures involved: class, number



    21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



    22) Total number of shares or debentures over which options held
    following this notification



    23) Any additional information

    None

    24) Name of contact and telephone number for queries


    Justin Hoskins, 01223 471471


    25) Name and signature of authorised company official responsible for
    making this notification

    Diane Mellett, Company Secretary


    Date of Notification 12 December 2002


                                    SCHEDULE 11

            NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS
 2. Name of company

    Cambridge Antibody Technology

    2) Name of director

    David Glover

    3) Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
    non-beneficial interest or in the case of an individual holder if it is a
    holding of that person's spouse or children under the age of 18 or in
    respect of a non-beneficial interest

    As in 2 above

    4) Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)

    Computershare Trustees Limited

    5) Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)

    As in 2 above

    6) Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary

    Allocation of partnership and matching shares under Inland Revenue Approved
    Share Incentive Plan

    7) Number of shares/amount of
    stock acquired

    610 (consisting of 305 partnership shares and 305 matching shares)

    8) Percentage of issued class

    0.0017%

    9) Number of shares/amount
    of stock disposed

    Nil

    10) Percentage of issued class

    N/A

    11) Class of security

    Ordinary 10 Pence

    12) Price per share

    #4.91

    13) Date of transaction

    11 December 2002

    14) Date company informed

    11 December 2002

    15) Total holding following this notification

    11,529

    16) Total percentage holding of issued class following this notification

    0.032%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
following this notification



23) Any additional information

None

24) Name of contact and telephone number for queries


Justin Hoskins, 01223 471471


25) Name and signature of authorised company official responsible for
making this notification

Diane Mellett, Company Secretary


Date of Notification 12 December 2002


                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

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