RNS No 0288x
CAMBRIDGE ANTIBODY TECHNOLOGY GROUP PLC


                    DEALINGS BY SUBSTANTIAL SHAREHOLDERS

1)  NAME OF COMPANY

CAMBRIDGE ANTIBODY TECHNOLOGY GROUP PLC

2)  NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

THE FLEMING MERCANTILE INVESTMENT TRUST PLC

3)  Please state whether notification indicates that it is in respect of holding
    of the Shareholder named in 2 above or in respect of a non-beneficial
    interest or in the case of an individual holder if it is a holding of that
    person's spouse or children under the age of 18

AS NAMED IN 2 ABOVE

4)  Name of the registered holder(s) and, if more than one holder, the number of
    shares held by each of them.

N/A

5)  Number of shares/amount of stock acquired.

N/A

6)  ( N/A %) of issued Class

7)  Number of shares/amount of stock disposed

N/A

8)  ( N/A %) of issued Class

9)  Class of security

ORDINARY SHARES OF 10P

10) Date of transaction

N/A

11) Date company informed

10 OCT 1997

12) Total holding following this notification

NO LONGER A NOTIFIABLE INTEREST

13) Total percentage holding of issued class following this notification

NO LONGER NOTIFIABLE

14) Any additional information

N/A

15) Name of contact and telephone number for queries

J C ASTON
01763 263233

16) Name and signature of authorised company official responsible for making
    this notification

    Date of Notification..10 OCTOBER 1997.......


END

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