RNS No 1452x
CAMBRIDGE ANTIBODY TECHNOLOGY
29th December 1997


Schedule 10 - Notification of Major Interests in Shares

1   Name of company:
Cambridge Antibody Technology

2   Name of shareholder having a major interest:
Merrill Lynch & Co Inc

3   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:
or Shareholder

4   Name of registered holder(s) and, if more than one holder, the number of
shares held by each of them:
As 2

5   Number of shares/amount of stock acquired:
2,634,225

6   Percentage of issued class:
11.88%

7   Number of shares/amount of stock disposed:


8   Percentage of issued class:


9   Class of security:
Ordinary 10p shares

10  Date of transaction:
22 December 1997

11  Date company informed:
25 December 1997

12  Total holding following this notification:
2,634,225

13  Total percentage holding of issued class following this notification:
11.88

14  Contact name for queries:
Diane Mellett

15 Contact telephone number:
01763 269 245

16  Name of company official responsible for making notification:
Diane Mellett Company Secretary

17  Date of notification:
December 28 1997

Additional Information:
Reports that Merrill Lynch & Co Inc have acquired holding previously held by
Mercury Asset management plc


END

HOLALLEEFILAFAD


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