Roche's Herceptin Extends Life In Aggressive Stomach Cancer
March 18 2009 - 3:16AM
Dow Jones News
Drugmaker Roche Holding AG (ROG.VX) said Wednesday that new data
shows its breast cancer drug Herceptin also shows benefits when
used to treat aggressive stomach cancer.
The results, from ToGA, a large international Phase III trial,
show that Herceptin significantly prolongs the lives of patients
with HER2-positive advanced stomach cancer.
"This is definitely good news," said Karl-Heinz Koch, an analyst
at Helvea, who rates the stock at buy.
"Herceptin was a breakthrough treatment for patients with
HER2-positive breast cancer and has become the foundation of care
across all stages of HER2-positive breast cancer", Bill Burns, CEO
of Roche's Pharmaceuticals Division, said in a statement. "The ToGA
study shows for the first time that Herceptin extends the lives of
patients in a cancer other than breast cancer."
Stomach cancer is the second most common cause of cancer-related
death in the world, with over 900,000 new cases diagnosed each
year, Roche said. Approximately 22% of stomach tumors overexpress
HER2, or Human Epidermal growth factor Receptor 2, a protein that
causes higher aggressiveness in tumors.
Herceptin, on the market since 1998, is marketed in the U.S. by
Genentech Inc (DNA), in Japan by Chugai Pharmaceutical Co Ltd
(4519.TO) and internationally by Roche.
Roche shares closed at CHF147.10 Tuesday, down 9.5% since the
start of 2009.
Company Web Site: http://www.roche.com
-By Hans Schoemaker, Dow Jones Newswires; +41-43-4438045;
hans.schoemaker@dowjones.com