TIDMTTM TIDMPLE 
 
Form 8.3 Plethora - Position Dealing Disclosure 
                                                                    FORM 8.3 
 
          PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY 
   A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 
                 Rule 8.3 of the Takeover Code (the "Code") 
 
1. KEY INFORMATION 
 
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(a) Full name of discloser:                        Baker Bros. Advisors LP 
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(b) Owner or controller of interests and short 
positions disclosed, if different from 1(a): 
The naming of nominee or vehicle companies is 
insufficient. For a trust, the trustee(s), settlor 
and beneficiaries must be named. 
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(c) Name of offeror/offeree in relation to whose   PLETHORA SOLUTIONS 
relevant securities this form relates:             HOLDINGS PLC 
Use a separate form for each offeror/offeree 
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(d) If an exempt fund manager connected with an 
offeror/offeree, state this and specify identity 
of offeror/offeree: 
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(e) Date position held/dealing undertaken:         February 24, 2016 
For an opening position disclosure, state the 
latest practicable date prior to the disclosure 
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(f) In addition to the company in 1(c) above, is   NO 
the discloser making disclosures in respect of any 
other party to the offer? 
If it is a cash offer or possible cash offer, 
state "N/A" 
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2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE 
 
If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the 
offeror or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant 
security. 
 
(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure 
relates following the dealing (if any) 
 
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Class of relevant security:                          1p Ordinary 
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                                               Interests           Short 
                                                                 positions 
                                         ----------------------------------- 
                                            Number       %     Number   % 
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(1) Relevant securities owned and/or      49,231,385    5.98 
 controlled: 
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(2) Cash-settled derivatives: 
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(3) Stock-settled derivatives (including 
 options) and agreements to 
 purchase/DEALING: 
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  TOTAL:                                  49,231,385    5.98 
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Class of relevant security:                     Fund raising warrants 
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                                               Interests           Short 
                                                                 positions 
                                         ----------------------------------- 
                                            Number       %     Number   % 
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(1) Relevant securities owned and/or      28,619,528   28.29 
 controlled: 
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(2) Cash-settled derivatives: 
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(3) Stock-settled derivatives (including 
 options) and agreements to 
 purchase/DEALING: 
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  TOTAL:                                  28,619,528   28.29 
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All interests and all short positions should be disclosed. 
 
Details of any open stock-settled derivative positions (including traded options), or agreements to purchase or 
sell relevant securities, should be given on a Supplemental Form 8 (Open Positions). 
 
(b) Rights to subscribe for new securities (including directors' and other employee options) 
 
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Class of relevant security in relation 
to which subscription right exists: 
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Details, including nature of the 
rights concerned and relevant 
percentages: 
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3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE 
 
Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 
1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt 
in. 
 
The currency of all prices and other monetary amounts should be stated. 
 
(a) Purchases and sales 
 
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 Class of relevant                         Number of 
      security        Purchase/DEALING        securities       Price per unit 
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    Ordinary 1p            Sale             350,000             3.75p 
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(b) Cash-settled derivative transactions 
 
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                                  Nature of 
                                   dealing 
                                    e.g. 
    Class of       Product     opening/closing   Number of 
    relevant     description    a long/short     reference    Price per unit 
    security       e.g. CFD       position,      securities 
                              increasing/reduc 
                              ing a long/short 
                                  position 
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(c) Stock-settled derivative transactions (including options) 
 
(i) Writing, selling, purchasing or varying 
 
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                                                       Type 
            Product    Writing,   Number of            e.g.          Option 
Class of  description purchasing securities Exercise American Expiry  money 
relevant   e.g. call  , selling,  to which    price      ,     date   paid/ 
security    option      varying    option   per unit European       received 
                         etc.      relates             etc.         per unit 
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(ii) Exercise 
 
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                   Product 
    Class of     description     Exercising/     Number of    Exercise price 
    relevant      e.g. call       exercised      securities      per unit 
    security        option         against 
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(d) Other dealings (including subscribing for new securities) 
 
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                    Nature of dealing 
 Class of relevant  e.g. subscription,      Details       Price per unit (if 
      security          conversion                           applicable) 
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4. OTHER INFORMATION 
 
(a) Indemnity and other dealing arrangements 
 
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Details of any indemnity or option arrangement, or any agreement or 
understanding, formal or informal, relating to relevant securities which may 
be an inducement to deal or refrain from dealing entered into by the person 
making the disclosure and any party to the offer or any person acting in 
concert with a party to the offer: 
Irrevocable commitments and letters of intent should not be included. If 
there are no such agreements, arrangements or understandings, state "none" 
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None 
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(b) Agreements, arrangements or understandings relating to options or derivatives 
 
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NONE 
 
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(c) Attachments 
 
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Is a Supplemental Form 8 (Open Positions) attached?                   No 
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