RNS Number:8526M
Metage Capital Limited
26 June 2003

                                                                      FORM SAR 3

Lodge with a RIS or Newstrack and the Takeover Panel. A copy must also be sent
to the company the shares of which are acquired.

                                                   Date of disclosure...26/06/03

   DISCLOSURE UNDER RULE 3 OF THE RULES GOVERNING SUBSTANTIAL ACQUISITIONS OF
                                SHARES ("SARs")



Date of acquisition 26th June 2003

Acquisition in PPL Therapeutics plc (name of company)


(1)  Class of voting shares          Number of shares/rights over shares  If rights over shares acquired,
     (eg ordinary shares)            acquired                             as opposed to the shares
                                                                          themselves, specify nature of
                                                                          rights
                                     
      ordinary shares                11,430,500 shares                    ...............................

                                     No rights


(2)  Resultant total holding of      Resultant total holding of rights    Total percentage
     voting shares (and % of total   over shares (and % of total voting
     voting shares in issue)         shares in issue)

      24,409,610 (20.59%)            ............................(   %)   .........................(%)


(3)   Party making disclosure

Metage Capital Limited


(4)  (a)  Name of person acquiring shares or rights over shares

          Metage Funds Limited

          and, if different, beneficial owner ..............................


     (b)  Names of any other persons acting by
          agreement or understanding (see SAR 5) .............................


Signed, for and on behalf of the party named in (3) above

Daron Sheehan


Telephone and extension number

0207 318 5273

                     ______________________________________


Note.   Under SAR 5, the holdings of and acquisitions by persons acting by
agreement or understanding must be aggregated and treated as a holding of or
acquisition by one person. Note 3 on SAR 5 requires persons who must aggregate
holdings to disclose certain disposals.

For full details of the SARs disclosure requirements, see Rules 3 and 5 of the
SARs. If in doubt, contact the Panel on Takeovers and Mergers, Monitoring
Section, Tel. No: 020 7638 0129.
E-mail: monitoring@disclosure.org.uk


                      This information is provided by RNS
            The company news service from the London Stock Exchange
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