RNS Number:4544P
PPL Therapeutics PLC
05 September 2003


Date:     Immediate, Friday 5 September 2003

Contact:  Geoff Cook, Chief Executive Officer
          PPL Therapeutics plc
          Telephone: 0131 440 4777

          Alistair Mackinnon-Musson
          Philip Dennis
          Hudson Sandler
          Telephone: 020 7796 4133
          Email: ppl@hspr.co.uk



                              PPL Therapeutics PLC

                                 Board Change


The Board of PPL Therapeutics plc ("PPL") is disappointed to announce that Bill
McCall has decided to resign as a non-executive director of the Board with
immediate effect.

PPL is currently in the process of restructuring its business following the
decision of PPL and Bayer to put its recAAT programme on hold, as announced on
18 June 2003.

The Company is currently presenting the options available to it at this time to
its largest shareholders in order to secure their support for the future
strategic direction of the business.

Options being explored are to restructure as a business based around its Fibrin
I technology and to bring in complementary intellectual property to broaden the
product portfolio. Other alternatives being reviewed include the outright sale
of the Company or its winding up.

The Board of PPL aims to conclude these discussions as quickly as possible and
reach a conclusion on the best way forward to enhance value for all
shareholders.



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