RNS Number : 2781I
  Artemis Investment Management
  17 November 2008
   


    FORM 8.3

    DEALINGS BY PERSONS WITH INTERESTS IN SECURITIES REPRESENTING 1% OR MORE
    (Rule 8.3 of the Takeover Code)

    1.    KEY INFORMATION

 Name of person dealing (Note 1)             Artemis Investment Management Ltd

 Company dealt in                                               Protherics Plc

 Class of relevant security to which the                           Ordinary 2p
 dealings being disclosed relate (Note 2)

 Date of dealing                                            14th November 2008


    2.    INTERESTS, SHORT POSITIONS AND RIGHTS TO SUBSCRIBE

 (a)  Interests and short positions (following dealing) in the class of
      relevant security dealt in (Note 3)

                                              Long              Short
                                              Number     (%)    Number  (%)

 (1) Relevant securities                      3,516,002  1.00%

 (2) Derivatives (other than options)

 (3) Options and agreements to purchase/sell

 Total                                        3,516,002  1.00%

 (b)  Interests and short positions in relevant securities of the company,
      other than the class dealt in (Note 3)

  Class of relevant security:                 Long         Short
                                              Number  (%)  Number  (%)

 (1) Relevant securities 

 (2) Derivatives (other than options)

 (3) Options and agreements to purchase/sell

 Total


    (c)    Rights to subscribe (Note 3)

 Class of relevant security:  Details




    3.    DEALINGS (Note 4)

    (a)    Purchases and sales

 Purchase/sale   Number of securities  Price per unit (Note 5)
                              750,000                   44.13p
 Sale

    (b)    Derivatives transactions (other than options)

 Product name,  Long/short (Note 6)  Number of securities  Price per unit (Note 5)
 e.g. CFD                            (Note 7)



    (c)    Options transactions in respect of existing securities
    (i)    Writing, selling, purchasing or varying

 Product              Writing,              Number of             Exercise  Type, e.g.         Expiry  Option
 name, e.g.           selling,              securities to         price     American,          date    money
 call option          purchasing,           which the                       European                   paid/received
                      varying etc.          option                          etc.                       per unit (Note
                                            relates                                                    5) 
                                            (Note 7)




    (ii)    Exercising

 Product name, e.g. call option  Number of securities  Exercise price per unit (Note 5)



    (d)    Other dealings (including new securities) (Note 4)

 Nature of transaction (Note 8)  Details  Price per unit (if applicable) (Note 5)



    4.    OTHER INFORMATION

    Agreements, arrangements or understandings relating to options or derivatives

    Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting
rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or
disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated.



 Is a Supplemental Form 8 attached? (Note 9)  NO


 Date of disclosure                                         17th November 2008

 Contact name                                                 Alistair Fleming

 Telephone number                                                0131 718 0411

 If a connected EFM, name of offeree/offeror with which                    N/A
 connected

 If a connected EFM, state nature of connection (Note 10)                  N/A


    Notes
    The Notes on Form 8.3 can be viewed on the Takeover Panel's website at www.thetakeoverpanel.org.uk

This information is provided by RNS
The company news service from the London Stock Exchange
 
  END 
 
RETILFILLTLDLIT

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