RNS Number:2318T
Cambridge Antibody Tech Group PLC
12 December 2003

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)  Name of company
Cambridge Antibody Technology


2)  Name of director
John Aston


3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest
As in 2 above


4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)
Computershare Trustees Limited


5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)
As in 2 above


6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary
Allocation of partnership and matching shares under Inland Revenue Approved
Share Incentive Plan


7)  Number of shares/amount of
    stock acquired
680 (consisting of 340 partnership and 340 matching shares)


8)  Percentage of issued class
0.001%


9)  Number of shares/amount
    of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10 pence shares


12) Price per share
#4.41


13) Date of transaction
12 December 2003


14) Date company informed
12 December 2003


15) Total holding following this notification
36,629


16) Total percentage holding of issued class following this notification
0.08%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01223 471471


25) Name and signature of authorised company official responsible for
    making this notification
Diane Mellett, Company Secretary


                       Date of Notification 12 December 2003


                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



1)  Name of company
Cambridge Antibody Technology


2)  Name of director
Peter Chambre


3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest
As in 2 above


4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)
Computershare Trustees Limited


5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)
As in 2 above


6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary
Allocation of partnership and matching shares under Inland Revenue Approved
Share Incentive Plan


7)  Number of shares/amount of
    stock acquired
680 (consisting of 340 partnership and 340 matching shares)


8)  Percentage of issued class
0.001%


9)  Number of shares/amount
    of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10 pence shares


12) Price per share
#4.41


13) Date of transaction
12 December 2003


14) Date company informed
12 December 2003


15) Total holding following this notification
10,469


16) Total percentage holding of issued class following this notification
0.02%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01223 471471


25) Name and signature of authorised company official responsible for
    making this notification
Diane Mellett, Company Secretary


    Date of Notification 12 December 2003



                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1)  Name of company
Cambridge Antibody Technology


2)  Name of director
David Glover


3)  Please state whether notification indicates that it is in respect of
    holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is a
holding of that person's spouse or children under the age of 18 or in respect of
a non-beneficial interest
As in 2 above


4)  Name of the registered holder(s) and, if more than one holder, the
    number of shares held by each of them (if notified)
Computershare Trustees Limited


5)  Please state whether notification relates to a person(s) connected
    with the Director named in 2 above and identify the connected person(s)
As in 2 above


6)  Please state the nature of the transaction. For PEP transactions
    please indicate whether general/single co PEP and if discretionary/non
    discretionary
Allocation of partnership and matching shares under Inland Revenue Approved
Share Incentive Plan


7)  Number of shares/amount of
    stock acquired
680 (consisting of 340 partnership and 340 matching shares)


8)  Percentage of issued class
0.001%


9)  Number of shares/amount
    of stock disposed
Nil


10) Percentage of issued class
Nil


11) Class of security
Ordinary 10 pence shares


12) Price per share
#4.41


13) Date of transaction
12 December 2003


14) Date company informed
12 December 2003


15) Total holding following this notification
12,469


16) Total percentage holding of issued class following this notification
0.03%


If a director has been granted options by the company please complete the
following boxes

17) Date of grant



18) Period during which or date on which exercisable



19) Total amount paid (if any) for grant of the option



20) Description of shares or debentures involved: class, number



21) Exercise price (if fixed at time of grant) or indication that price
    is to be fixed at time of exercise



22) Total number of shares or debentures over which options held
    following this notification



23) Any additional information



24) Name of contact and telephone number for queries
Diane Mellett 01223 471471


25) Name and signature of authorised company official responsible for
    making this notification
Diane Mellett, Company Secretary


    Date of Notification 12 December 2003


                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

RDSEAKAAFSSDFFE