RAYMOND,
AB, June 3, 2024 /CNW/ - A groundbreaking
12-week fully blinded, randomized, controlled trial known as the
NUTRIMUM study, recently published in the British Journal of
Psychiatry (BJPsych Open), highlights the efficacy and safety
of Hardy Nutritionals' Daily Essential Nutrients (DEN) in treating
symptoms of antenatal depression. A follow-up study compared the
health of the babies born to mothers taking DEN against babies from
healthy mothers taking regular prenatal vitamins and/or
pharmaceutical antidepressants. This research provides compelling
evidence that this broad-spectrum micronutrient formula offers
significant benefits over antidepressants and regular prenatal
supplements for pregnant women and their babies.
Key Findings for the Mothers:
Improved Mental Health
Outcomes
Daily Essential Nutrients (DEN) significantly improved both
self-rated and clinician-rated depression, global functioning, and
sleep quality in pregnant women relative to placebo controls, with
nearly double the number of women taking micronutrients identifying
themselves as being "much" or "very much" improved. Women with
personality difficulties benefited the most from the micronutrients
(i.e. those with difficulty making & keeping friends,
impulsive, untrusting, short-tempered, worriers,
perfectionists).
Safety, Tolerability, and
Efficacy
The researchers concluded that the micronutrients were safe, and
the "outcomes were comparable to those obtained using psychotherapy
but achieved with much less contact." Furthermore, improvements in
global functioning show that "the impact of micronutrients is
likely not specific to one dimension of pathology (e.g.
depression), but may better serve as an overall metabolic tune-up."
"These findings align with the growing body of literature
highlighting the potential advantage of an abundant nutritional
environment in improving brain health."
For full access, see the following link:
https://www.cambridge.org/core/journals/bjpsych-open/article/efficacy-and-safety-of-a-mineral-and-vitamin-treatment-on-symptoms-of-antenatal-depression-12week-fully-blinded-randomised-placebocontrolled-trial-nutrimum/84BC34CD9F2689AE9D790F69B5D7C673
Key Findings for the Babies:
Enhanced Neonatal
Outcomes
Babies from moms who took DEN for depression during pregnancy
were significantly better off than newborns from moms taking
pharmaceutical antidepressants on 6 out of 7 physiological and
neurological measures (habituation to disturbances, orientation to
sights and sounds, motor control, regulation of state, autonomic
stability, and normal reflexes).
The "DEN babies" even outperformed babies from otherwise
healthy, unmedicated moms on 3 of the 7 measures (habituation to
disturbances, motor control, and autonomic stability)!
Optimal Gestation and
Birth
Micronutrient-exposed infants were also more likely to be
carried to full term than infants from healthy, unmedicated mothers
and mothers taking antidepressants, which bodes well for the
lifelong outcomes of the child.
For full access, see the following link:
https://www.sciencedirect.com/science/article/pii/S0378378224000173?via%3Dihub
Holistic Approach to Mental Health in Pregnancy
The researchers determined that the micronutrients successfully
improved psychological functioning in the mothers and birth
outcomes for the infants, mitigating some of the known risks to
infants which can result from antenatal depression in the
mothers.
The comprehensive nature of Daily Essential Nutrients, which
includes a wide range of vitamins and minerals, supports overall
mental health and well-being. This holistic approach addresses the
nutritional deficiencies that often contribute to depressive
symptoms, providing a more natural and balanced treatment
option.
The researchers postulated that the benefits of Daily Essential
Nutrients compared to typical over-the-counter prenatal supplements
may be due to "a higher dose [and a] more balanced variety of
nutrients."
"Overall, our results indicate that micronutrient
supplementation given above the Recommended Dietary Allowance
during pregnancy appears safer relative to existing treatment
options for women with depression and may even launch these infants
to a better start in life."
Note: There are no financial ties between Hardy Nutritionals and
the University of Canterbury or
any of the researchers.
Sources:
1. "Efficacy and safety of a mineral and vitamin treatment on
symptoms of antenatal depression: 12-week fully blinded randomized
placebo-controlled trial (NUTRIMUM)"
Journal: BJPsych Open
Authors:
Hayley A. Bradley, Elena
Moltchanova, Roger T. Mulder,
Lesley Dixon, Jacki Henderson, and Julia J. Rucklidge
2. "Effect of antenatal micronutrient or antidepressant exposure
on Brazelton neonatal behavioral assessment scale within 1 month of
birth"
Journal: Early Human
Development
Authors: Campbell et al.
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SOURCE Hardy Nutritionals