CHICAGO, Aug. 1, 2024 /PRNewswire/ -- The
global Single Use Bioreactors Market is expected to grow from
USD 4.4 billion in 2024 to
USD 9.1 billion by 2029, at a CAGR of
15.4%. The single-use bioreactors (SUBs) market is driven by
factors such as the growing adoption of single-use technologies by
SMEs, CDMOs, and CMOs, the benefits of SUBs over traditional
stainless-steel bioreactors, and the expanding biologics and
biosimilars market. These bioreactors are favored for their lower
capital investment, reduced water and energy consumption, and
flexibility. However, challenges such as leachables and
extractables issues, regulatory hurdles, and PFAS restrictions may
impact growth. The market is bolstered by opportunities in hybrid
facilities, which combine single-use and traditional systems for
cost efficiency and flexibility. Despite these advantages, concerns
about the potential breakage of single-use bags, which can lead to
contamination and significant financial losses, pose challenges. In
2023, single-use bioreactor systems and stirred-tank bioreactors
dominated the market, with North
America leading regional markets due to its strong
biopharmaceutical R&D presence. Key players include Sartorius
AG, Danaher Corporation, Thermo Fisher Scientific Inc., and Merck
KGaA.
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Sartorius AG: Leading Provider of Single-Use Bioreactor
Solutions
Sartorius AG is a prominent player in the single-use bioreactors
market, catering to biopharmaceutical and pharmaceutical companies,
CMOs, and CROs. The company stands out for its comprehensive range
of customer-centric, technology-driven solutions and significant
investments in R&D. Its extensive product lineup, which
includes high-quality single-use bioreactors, is a key factor in
its growing market share. Sartorius AG's robust global presence and
ongoing expansion in both developed and emerging markets position
it for continued growth in the single-use bioreactors sector during
the forecast period.
Danaher Corporation: Key Innovator in Single-Use
Bioreactors
Danaher Corporation, through its subsidiary Cytiva, offers
advanced cell culture, filtration, separation, and purification
technologies for the medical, biopharmaceutical, and food &
beverage industries. Its strong portfolio of single-use bioreactor
solutions makes it a leading player in the market. Danaher's
bioprocessing technologies facilitate the development and
commercialization of drugs, plasma, and vaccines, underscoring its
significant role in the single-use bioreactors market.
Thermo Fisher Scientific, Inc.: Comprehensive Single-Use
Bioreactor Solutions Provider
Thermo Fisher Scientific, Inc. provides a broad range of
single-use bioreactor products, effectively addressing diverse
market needs. As a leading market player, Thermo Fisher leverages its extensive product
offerings and strong market presence to influence trends and
customer preferences. Continuous investment in R&D enables the
company to stay at the cutting edge of technological advancements,
addressing emerging challenges and opportunities in
bioprocessing.
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Product Segmentation: Single-Use Bioreactor Systems Lead the
Market
In 2023, the single-use bioreactors market is divided into
several product categories: single-use bioreactor systems,
single-use media bags, single-use assemblies, and other products
(such as single-use vessels, sensors, tubing, connectors, software,
control systems, and probes). The single-use bioreactor systems
segment held the largest market share due to their lower initial
investment requirements, reduced operational costs from simplified
processes, and minimal environmental impact thanks to recyclable
components. These advantages have significantly boosted the
adoption of single-use bioreactor systems in biopharmaceutical
applications.
Type Segmentation: Stirred-Tank Bioreactors Dominate
The single-use bioreactors market is segmented by type into
stirred-tank, wave-induced, bubble-column, and other bioreactors
(including hybrid designs and bioreactors with vertically
perforated discs). In 2023, stirred-tank bioreactors represented
the largest segment. Known for their versatility and scalability,
stirred-tank bioreactors are extensively used in the pharmaceutical
and biotechnology sectors. Their impeller-driven design ensures
even distribution of gases and nutrients, making them ideal for
producing recombinant proteins, vaccines, and monoclonal
antibodies.
Molecule Type Segmentation: Monoclonal Antibodies
Lead
The single-use bioreactors market is also segmented by molecule
type into monoclonal antibodies (mAbs), vaccines, stem cells,
gene-modified cells, and therapeutic proteins & peptides. In
2023, the monoclonal antibodies segment had the largest share,
driven by the expanding pharmaceutical R&D pipeline, increasing
cancer incidence, and rising demand for cancer therapies.
Cell Type Segmentation: Mammalian Cells Prevail
In terms of cell types, the market is divided into mammalian
cells, bacterial cells, yeast cells, and other cells (such as
insect and plant cells). The mammalian cells segment held the
largest market share in 2023. This is due to the widespread use of
mammalian cells in bioprocessing, known for their sophisticated
metabolic functions, which drive the segment's growth.
Application Segmentation: Bioproduction Leads
The market is segmented by application into bioproduction,
process development, and research & development (R&D). The
bioproduction segment accounted for the largest share in 2023,
attributed to the growing use of single-use bioreactors in
biomanufacturing, increased regulatory approvals for
biopharmaceuticals, the rise of biosimilars, and patent expirations
of blockbuster drugs.
End-User Segmentation: Pharmaceutical & Biotechnology
Companies Dominate
Based on end users, the market is segmented into pharmaceutical
& biotechnology companies, contract research organizations
(CROs) & contract manufacturing organizations (CMOs), and
academic & research institutes. The pharmaceutical &
biotechnology companies segment was the largest in 2023 due to
heightened R&D activities and increased production of biologics
and biosimilars.
Regional Insights: North
America and Asia Pacific Lead
The market is divided by region into North America, Europe, Asia
Pacific, Latin America, the
Middle East, and Africa. In 2023, North America held the largest market share,
followed by Europe. North America's substantial market share is
driven by the presence of major players and growing demand for
personalized medicine and biologics. Meanwhile, the Asia Pacific region is anticipated to
experience the highest compound annual growth rate (CAGR), fueled
by the rising demand for biosimilars, expanding biopharmaceutical
manufacturing capacities, and a growing contract manufacturing
sector.
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