The approximately 3,000 fragrance-producing
ingredients in current use have all been evaluated; those not yet
published await peer-review
MAHWAH,
N.J., Sept. 20, 2024 /PRNewswire/ -- The
Research Institute for Fragrance Materials (RIFM) Safety Assessment
Program has published peer-reviewed safety assessments covering
over 2,000 fragrance materials in the peer-reviewed literature.
RIFM President Anne Marie Api,
Ph.D., Fellow ATS, highlighted the achievement at the Institute's
58th Annual Meeting last week.
"RIFM has published thousands of peer-reviewed datasheets, group
summaries, evaluations, and research papers addressing the safe use
of scent-producing ingredients since the early 1970s," Dr. Api
explained. "In the 21st century, we pivoted to research
and next-generation risk assessments (NGRAs) focused on animal-free
science, strategically using new approach methodologies (NAMs) to
save well over half a million animals."
RIFM does no animal testing for any of its human health
endpoints.
Danielle Botelho, Ph.D., Director
of Scientific Operations at RIFM elaborated, "This milestone is
significant, given that the complete palette of discrete fragrance
ingredients is approximately 2,200 materials in any given year. In
addition to the discrete materials, the fragrance-producing palette
includes approximately 900 Natural Complex Substance (NCS)
ingredients distilled from natural sources. RIFM anticipates
completing safety assessments for the first round of NCS by
2028."
About RIFM
The Research Institute for Fragrance Materials (RIFM) assesses
the safety of fragrance ingredients by the most current,
internationally accepted guidelines—and has done so since its
founding in 1966. RIFM's fragrance ingredient Safety Assessment
program draws from its comprehensive database of over 80,000
references, which include approximately 200,000 human health and
environmental endpoints and scientific literature. All RIFM's
findings are reviewed and approved by an independent panel of
academic experts, The Expert Panel for Fragrance Safety
(fragrancesafetypanel.org), with no ties to the fragrance industry,
and submitted for peer-reviewed publication in the scientific
literature. In addition, all of RIFM's published Safety Assessments
and Research are free to the public via
FragranceMaterialSafetyResource.elsevier.com.
Contact:
Gary Sullivan
gsullivan@rifm.org
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SOURCE Research Institute for Fragrance Materials