Investor2014
5 hours ago
Nothing Anavex I can find in that program, but this: blarcamesine (Anavex 2-73) / Anavex - LARVOL DELTA indicates an embargoed behind AAIC login presentation.
Blarcamesine in Early Alzheimer Disease Phase 2b/3 Randomized Clinical Trial (AAIC 2024) - "In this phase 2b/3 randomized clinical trial, we found that among participants with early AD, blarcamesine significantly slowed clinical progression on prespecified primary outcome global and cognitive measures at 48 weeks in the ITT population. These results suggest that blarcamesine may be an effective, safe, and novel scalable oral treatment for early AD."
Clicking on the link above, the title points to an AAIC login page.
crescentmotor
7 hours ago
As amply demonstrated by the comments on his article, relying on Lane Simonian, a retired history professor, for advice on SAVA is akin to being dependent on kund on Investors Hub for advice concerning AVXL. Lane draws his conclusions about Simufilam's efficacy past one year of treatment based on his complete misunderstanding of the six month Simufilam withdrawal study where he doesn't understand that the "placebo" group (admittedly a confusing term used by SAVA) had already been on Simufilam for one year. As a result, the so-called "placebo" group's statistics were improved from the lingering positive carryover effects of prior Simufilam administration. Very few people understand that nuance in the trial results and SAVA indeed could have done a much better job reporting out the trial results. SAVA should not have named the withdrawal group "placebo" as it really wasn't (given the normal/usual structure of trials) and this caused a lot of confusion in interpreting the trial results. Lane repeatedly questions the MOA of Simufilam without acknowledging that several independent companies and distinguished scientists had conducted studies confirming the MOA. In completed open label trials (placebo controlled for the withdrawal phase), the bottom line is that 47 patients with mild Alzheimer's disease who received Simufilam treatment continuously for two years had no decline in ADAS-Cog scores as a group. 40 other patients who participated in the six month drug withdrawal study and did not receive Simufilam for six months and then were placed back on Simufilam suffered only a one point decline in ADAS-Cog. Two safety inspections by the DSMB have resulted in recommendations that SAVA's two ongoing Phase III trials should continue. Blinded interim safety analysis have shown that Simufilam is not associated with treatment-emergent ARIA. Simufilam is an oral drug and treatment does not require infusions or follow-on MRIs. Last patient visit in the first Phase III trial (RETHINK) is expected in October 2024 with top line data expected shortly thereafter.
Investor Presentations:
https://www.cassavasciences.com/company-presentations
poguemahone
15 hours ago
Here goes my technical analysis: the closing price of $6.48 represents the lower channel of the band that extended through to $6.73. $6.73 represents the resistance zone, as this price has been tested, retested, and retreated. Bollinger bands and stochastic modeling indicate the price could go higher, but it certainly could go lower as well. The key to watch for is if the color is green, the price is higher, which then means it could go lower or remain unchanged, as traders generally want to make money. Look for the stock to go up or down, but it might also remain unchanged if buyers lack conviction. It’s too hard to call right now, so I’ll get back to you tomorrow at 4:30 to let you know what already happened.
123tom
16 hours ago
Looking at EW...
Like you said ,counting waves can be a little tricky. You can see 5 waves up, but also it could extend to 7 waves. I've even counted 9 waves in a finished pattern at times.
Sometimes it helps when I go back to the bottom and start over. I can clearly see the 1st upwave, from 3.25/3.40 bottom to finish peak around 4.50/4.60. As Wave 1
Wave 2 pulls back and holds support at 3.50/3.65/3.73.
Then we get the latest surging upwave that peaked at 6.80. This is the more difficult wave to analyze because depending on how you count it, could be a wave 3,4,and 5 finished.Or... it could be just one wave 3, you know ,like counting 1 of 5 of 3, 2 of 5 of 3, etc. The pullback around 6.40 is looking zig zaggy like a Wave 4.... so that's why I'm thinking the surge to 6.80 was only a Wave 3 , now sideways zig zag is wave 4, and we could anticipate wave 5 to target 7.60-8.40 area as a finished pattern.
RedShoulder
18 hours ago
Short Report just out: 07/15/2024 18,440,980
07/15/2024 18,440,980 3.45 802,783 22.97
06/28/2024 17,825,737 (14.89) 1,692,163 10.53
06/14/2024 20,944,467 (4.00) 1,071,745 19.54
05/31/2024 21,816,277 (0.20) 1,033,741 21.10
05/15/2024 21,860,442 2.68 1,029,913 21.23
https://nasdaqtrader.com/Trader.aspx?id=ShortInterest