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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): September 29, 2023
JAGUAR HEALTH, INC.
(Exact name of registrant as specified in its charter)
Delaware |
001-36714 |
46-2956775 |
(State or other jurisdiction of incorporation) |
(Commission File Number) |
(IRS Employer Identification No.) |
200 Pine Street, Suite 400
San Francisco, California |
94104 |
(Address of principal executive offices) |
(Zip Code) |
Registrant’s telephone number, including
area code: (415) 371-8300
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):
¨ | Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
¨ | Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
¨ | Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
¨ | Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company ¨
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨
Securities registered pursuant to Section 12(b) of the Act:
Title of each class |
Trading
Symbol(s) |
Name of each exchange on which
registered |
Common Stock, Par Value $0.0001 Per Share |
JAGX |
The Nasdaq Capital Market |
Item 1.01 Entry into a Material Definitive Agreement.
Royalty Interest Global Amendments
On September 29, 2023, Jaguar Health, Inc.
(the “Company”) entered into amendments (the “Royalty Interest Global Amendments”) to (i) the royalty interest
in the original principal amount of $12 million (the “October 2020 Royalty Interest”) with Iliad Research and Trading,
L.P. (“Iliad”), as amended, (ii) the royalty interest in the original principal amount of $12 million (the “December 2020
Royalty Interest”) with Uptown Capital, LLC (f/k/a Irving Park Capital, LLC; “Uptown”), as amended, and (iii) the
royalty interest in the original principal amount of $12 million (the “August 2022 Royalty Interest” and, together with
the October 2020 Royalty Interest and the December 2020 Royalty Interest, the “Royalty Interests”) with Streeterville
Capital, LLC (“Streeterville” and, together with Iliad and Uptown, the “Investors”), pursuant to which, beginning
on January 1, 2026, the monthly Royalty Payment under each of the Royalty Interests shall be the greater of (a) $750,000.00,
and (b) the actual Royalty Payment amount the respective Investor is entitled to for such month pursuant to the terms of such Royalty
Interest. In addition, pursuant to an additional amendment to the August 2022 Royalty Interest with Streeterville, the Company is
prohibited from making prepayments of the Royalty Repayment Amount under the August 2022 Royalty Interest.
As a material consideration for Investors’
agreement to enter into the Royalty Interest Global Amendments, the Company agreed to issue to (i) Iliad warrants to purchase up
to 232,500 shares of the Company’s common stock, par value $0.0001 per share (the “Common Stock”), (ii) Uptown
warrants to purchase up to 262,500 shares of the Common Stock, and (iii) Streeterville warrants to purchase up to 255,000 shares
of the Common Stock, at an exercise price of $0.37 per share (collectively, the “Warrants”).
The Warrants may be exercisable for cash or on
a cashless basis at any time and from time to time during the period commencing on September 29, 2023 (the “Issuance Date”)
and ending on the five-year anniversary of the Issuance Date.
The foregoing descriptions of the Royalty Interest
Global Amendments and the Warrants do not purport to be complete and are qualified in their entirety by reference to the Royalty Interest
Global Amendments and the form of Warrant, copies of which are filed herewith as Exhibits 4.1, 4,2, 4.3, 4.4 and 4.5, respectively, and
incorporated herein by reference.
Exchange Transaction
On September 29, 2023, the Company entered
into a privately negotiated exchange agreement with Uptown (the “Exchange Agreement”), pursuant to which the Company issued
an aggregate of 118 shares of the Company’s newly authorized Series I Convertible Preferred Stock (the “Series I
Preferred Stock”) to Uptown, at an effective exchange price per share equal to the market price (defined as the Minimum Price under
Nasdaq Listing Rule 5635(d)) as of the date of the Exchange Agreement, in exchange for a $1,500,000.00 reduction in the outstanding
balance of the December 2020 Royalty Interest (the “Exchange Transaction”).
Subject to the terms of the Series I Preferred
Stock, each share of Series I Preferred Stock is convertible into shares of the Company’s Common Stock (the “Conversion
Shares”). The terms of the Series I Preferred Stock are set forth in a Certificate of Designation of Preferences, Rights and
Limitations of Series I Convertible Preferred Stock (the “Certificate of Designation”) filed with the Secretary of State
of Delaware and effective on September 29, 2023. A description of the terms of the Series I Preferred Stock is included under
Item 5.03 of this Current Report and is incorporated herein by reference.
The Exchange Agreement includes representations,
warranties, and covenants customary for a transaction of this type.
The foregoing summary of the Exchange Agreement
does not purport to be complete and is subject to, and qualified in its entirety by the Exchange Agreement, a copy of which is attached
as Exhibit 10.1 to this Current Report on Form 8-K and is incorporated herein by reference.
Item 2.03 Creation
of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant.
The information contained
above in Item 1.01 under the heading “Royalty Interest Global Amendments” is hereby incorporated by reference into this Item
2.03 in its entirety.
Item 3.02 Unregistered Sales of Equity Securities.
The information contained above in Item 1.01 is
hereby incorporated by reference into this Item 3.02 in its entirety. The Series I Preferred Shares were issued in reliance on the
exemption from registration provided under Section 3(a)(9) of the Securities Act of 1933, as amended.
Item 5.03 Amendments
to Articles of Incorporation or Bylaws; Change in Fiscal Year.
Series I Certificate of Designation
As disclosed under Items 1.01 and 3.02 above,
in connection with the Exchange Transaction, the Company agreed to issue shares of Series I Preferred Stock to Uptown. The preferences,
rights, limitations and other matters relating to the Series I Preferred Stock are set forth in the Certificate of Designation. The
shares of Series I Preferred Stock rank pari passu with shares of the Common Stock as to distributions of assets upon liquidation,
dissolution or winding up of the Company. The Certificate of Designation is filed as Exhibit 3.1 to this Current Report on Form 8-K.
The Certificate of Designation authorizes the
Company to issue 118 of its 4,475,074 authorized shares of preferred stock as Series I Preferred Stock. The original issue price
for the Series I Preferred Stock is $12,711.864 per share, subject to appropriate adjustment in the event of any stock dividend,
stock split, combination or other similar recapitalization with respect to the Series I Preferred Stock.
The following is a summary of the principal terms
of the Series I Preferred Stock as set forth in the Certificate of Designation:
Dividends
Holders of shares of Series I Preferred Stock
will be entitled to receive dividends equal, on an as-if-converted to shares of Common Stock basis, to and in the same form as dividends
actually paid on shares of the Common Stock when, as, and if such dividends are paid on shares of the Common Stock.
Voting Rights
The Series I Preferred Stock shall have no
voting rights. As long as any shares of Series I Preferred Stock are outstanding, the Company shall not, without the affirmative
vote of the holders of a majority of the then outstanding shares of the Series I Preferred Stock, (a) alter or change adversely
the powers, preferences or rights given to the Series I Preferred Stock or alter or amend the Certificate of Designation or (b) enter
into any agreement with respect to any of the foregoing.
Liquidation Rights
In the event of any voluntary or involuntary liquidation,
dissolution or winding up of the Company (each, a “Liquidation Event”), the holders of shares of Series I Preferred Stock
will be entitled to receive out of the assets of the Company the same amount that a holder of shares of the Common Stock would receive
if the shares of Series I Preferred Stock were fully converted to Common Stock, which amounts shall be paid pari passu with all holders
of Common Stock.
Conversion
Subject to the Beneficial Ownership Limitation
(as defined below), each share of Series I Preferred Stock is convertible into 48,151 shares of Common Stock (quotient obtained from
dividing the $12,711.864 stated value of each share of Series I Preferred Stock by a conversion price of $0.264), which conversion
ratio is subject to adjustment for subject to adjustment for reverse and forward stock splits, stock dividends, stock combinations and
other similar transactions of the Common Stock.
In addition, the Company shall not effect any
conversion of the Series I Preferred Stock, and a holder thereof shall not have the right to convert any portion of the Series I
Preferred Stock, to the extent that, after giving effect to the conversion set forth on the applicable Notice of Conversion, such holder
(together with such holder’s Affiliates and Attribution Parties (both as defined in the Certificate of Designation)) would beneficially
own in excess of the Beneficial Ownership Limitation. The “Beneficial Ownership Limitation” shall be 9.99% of the number of
shares of Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issuable upon conversion
of the Series I Preferred Stock held by the applicable holder. A holder, upon notice to the Company, may increase or decrease the
Beneficial Ownership Limitation provisions in the Certificate of Designation applicable to its Series I Preferred Stock provided
that the Beneficial Ownership Limitation in no event exceeds 9.99% of the number of shares of the Common Stock outstanding immediately
after giving effect to the issuance of shares of Common Stock upon conversion of the Series I Preferred Stock held by the holder
and the relevant provisions of the Certificate of Designation shall continue to apply.
Trading Market
There is no established trading market for any
of the Series I Preferred Stock, and we do not expect a market to develop. We do not intend to apply for a listing for any of the
Series I Preferred Stock on any securities exchange or other nationally recognized trading system. Without an active trading market,
the liquidity of the Series I Preferred Stock will be limited.
The foregoing description of the Certificate of
Designation does not purport to be complete and is qualified in its entirety by reference to the full text of the Certificate of Designation,
a copy of which is filed as Exhibit 3.1 to this Current Report and is incorporated by reference herein.
Item 9.01 Financial Statements and Exhibits.
(d) Exhibits
Exhibit
No. |
|
Description |
3.1 |
|
Certificate of Designation of Preferences, Rights and Limitations of Series I
Convertible Preferred Stock. |
4.1 |
|
Global Amendment No. 2, dated September 29, 2023, by and between Jaguar
Health, Inc. and Iliad Research and Trading, L.P. |
4.2 |
|
Global Amendment No. 2, dated September 29, 2023, by and between Jaguar
Health, Inc. and Uptown Capital, LLC. |
4.3 |
|
Global Amendment, dated September 29, 2023, by and between Jaguar Health, Inc.
and Streeterville Capital, LLC. |
4.4 |
|
Global Amendment No. 2, dated September 29, 2023, by and between Jaguar
Health, Inc. and Streeterville Capital, LLC. |
4.5 |
|
Form of Warrant. |
10.1 |
|
Exchange Agreement, dated September 29, 2023, by and between Jaguar Health, Inc.
and Uptown Capital, LLC. |
104 |
|
Cover Page Interactive Data File (embedded within the inline XBRL document) |
SIGNATURES
Pursuant to the requirements of the Securities
Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly
authorized.
|
JAGUAR HEALTH, INC. |
|
|
|
By: |
/s/ Lisa A. Conte |
|
|
Name: |
Lisa A. Conte |
|
|
Title: |
President and Chief Executive Officer |
Date: October 5, 2023
Exhibit 3.1
JAGUAR HEALTH, INC.
CERTIFICATE OF DESIGNATION OF PREFERENCES,
RIGHTS AND LIMITATIONS
OF
SERIES I CONVERTIBLE
PREFERRED STOCK
Pursuant to Section 151 of the
General Corporation Law of the State of Delaware
The undersigned, Lisa A. Conte and Carol R. Lizak,
do hereby certify that:
1. They
are the Chief Executive Officer/President and Chief Financial Officer, respectively, of Jaguar Health, Inc., a Delaware corporation
(the “Corporation”).
2. The
following resolutions were duly adopted by the board of directors of the Corporation (the “Board of Directors”):
WHEREAS, the certificate of
incorporation of the Corporation provides for a class of its authorized stock known as preferred stock, consisting of 4,475,074 shares,
$0.0001 par value per share, issuable from time to time in one or more series, of which 137 shares designated as Series G Convertible
Preferred Stock (the “Series G Preferred Stock”) and 80 shares designated as Series H Convertible Preferred
Stock (the “Series H Preferred Stock”) are issued and outstanding as of the date hereof;
WHEREAS, the Board of Directors
is authorized to fix the dividend rights, dividend rate, voting rights, conversion rights, rights and terms of redemption and liquidation
preferences of any wholly unissued series of preferred stock and the number of shares constituting any series and the designation thereof,
of any of them; and
WHEREAS, it is the desire
of the Board of Directors, pursuant to its authority as aforesaid, to fix the rights, preferences, restrictions and other matters relating
to a series of the preferred stock, which shall consist of 118 shares of the preferred stock which the Corporation has the authority to
issue, as follows:
NOW, THEREFORE, BE IT RESOLVED,
that the Board of Directors does hereby provide for the issuance of a series of preferred stock for cash or exchange of other securities,
rights, powers, property, or other lawful consideration and does hereby fix and determine the rights, preferences, restrictions and other
matters relating to such series of preferred stock as follows:
TERMS OF Series I
CONVERTIBLE PREFERRED STOCK
Section 1. Definitions. For the purposes hereof, the following
terms shall have the following meanings:
“Affiliate”
means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under common control
with a Person, as such terms are used in and construed under Rule 405 of the Securities Act.
“Attribution
Parties” shall have the meaning set forth in Section 6.
“Beneficial
Ownership Limitation” shall have the meaning set forth in Section 6.
“Business
Day” means any day except any Saturday, any Sunday, any day which is a federal legal holiday in the United States or any day
on which banking institutions in the State of New York are authorized or required by law or other governmental action to close.
“Buy-In”
shall have the meaning set forth in Section 6.
“Commission”
means the United States Securities and Exchange Commission.
“Common
Stock” means the Corporation’s common stock, par value $0.0001 per share, and stock of any other class of securities into
which such securities may hereafter be reclassified or changed.
“Common
Stock Equivalents” means any securities of the Corporation or the Subsidiaries which would entitle the holder thereof to acquire
at any time Common Stock, including, without limitation, any debt, preferred stock, rights, options, warrants or other instrument that
is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock.
“Company
Conversion Notice” means a notice delivered by the Corporation to effect a Mandatory Conversion of all the outstanding Series I
Preferred Stock, provided that the effective date of such Mandatory Conversion shall be no less than ten (10) Business Days following
the date that such notice is deemed to have been given.
“Conversion
Date” shall have the meaning set forth in Section 6(a).
“Conversion
Price” for each share of Series I Preferred Stock shall be, unless otherwise provided in this Certificate of Designation,
equal to $0.264, subject to adjustment for reverse and forward stock splits, stock dividends, stock combinations and other similar transactions
of the Common Stock that occur after the Original Issue Date as set forth in Section 7 hereof.
“Conversion
Ratio” for each share of Series I Preferred Stock shall be equal to the Stated Value divided by the applicable Conversion
Price.
“Conversion
Shares” means, collectively, the shares of Common Stock issuable upon conversion of the shares of Series I Preferred Stock
in accordance with the terms hereof.
“Delaware
Courts” shall have the meaning set forth in Section 8(b).
“Dividend Shares”
shall have the meaning given such term in Section 3.
“Fundamental Transaction”
shall have the meaning set forth in Section 7(d).
“Holder”
shall have the meaning given such term in Section 2.
“Liquidation
Event” shall have the meaning set forth in Section 5.
“Mandatory
Conversion” shall have the meaning set forth in Section 6.
“Mandatory
Conversion Date” shall have the meaning set forth in Section 6.
“Mandatory
Conversion Determination” shall have the meaning set forth in Section 6.
“Notice
of Conversion” shall have the meaning set forth in Section 6(a).
“Original
Issue Date” means the date of the first issuance of any shares of the Series I Preferred Stock regardless of the number
of transfers of any particular shares of Series I Preferred Stock.
“Person”
means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability company,
joint stock company, government (or an agency or subdivision thereof) or other entity of any kind.
“Securities
Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder.
“Series I
Preferred Stock” shall have the meaning set forth in Section 2.
“Share
Delivery Date” shall have the meaning set forth in Section 6(c)(i).
“Stated
Value” means $12,711.864.
“Trading
Day” means a day on which the principal Trading Market is open for business.
“Trading
Market” means any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date
in question: the NYSE American, the Nasdaq Capital Market, the Nasdaq Global Market, the Nasdaq Global Select Market, or the New York
Stock Exchange (or any successors to any of the foregoing).
“Transfer
Agent” means American Stock Transfer & Trust Company, the current transfer agent of the Corporation with a mailing
address of 59 Maiden Lane, New York, New York and a facsimile number of 718-236-4588, and any successor transfer agent of the Corporation.
Section 2. Designation,
Amount and Par Value. This series of preferred stock shall be designated as Series I Convertible Preferred Stock (the “Series I
Preferred Stock”) and the number of shares so designated shall be 105 (One Hundred Five) (each holder of the Series I
Preferred Stock a “Holder” and collectively, the “Holders”). Each share of Series I Preferred
Stock shall have a par value of $0.0001 per share. The Series I Preferred Stock will initially be issued in book-entry form.
Section 3. Dividends.
Holders of shares of Series I Preferred Stock will be entitled to receive dividends equal, on an as-if-converted to shares of Common
Stock basis, to and in the same form as dividends actually paid on shares of the Common Stock when, as, and if such dividends are paid
on shares of the Common Stock. The dividends shall be paid (to the extent accrued and not previously paid) upon the Mandatory Conversion
Date. Notwithstanding the foregoing, to the extent that a Holder’s right to participate in any stock dividend declared on the Common
Stock to which such Holder is entitled to (“Dividend Shares”) would result in such Holder exceeding the Beneficial
Ownership Limitation, then such Holder shall not be entitled to participate in any such dividend to such extent (or in the beneficial
ownership of any Dividend Shares as a result of such dividend to such extent) and the portion of such Dividend Shares that would cause
such Holder to exceed the Beneficial Ownership Limitation shall be held by the Corporation in abeyance for the benefit of such Holder
(which shall not give the Holder any power to vote or dispose of such Dividend Shares) until such time, if ever, as such Holder’s
beneficial ownership thereof would not result in such Holder exceeding the Beneficial Ownership Limitation.
Section 4. Voting Rights. Except as otherwise provided herein or as
otherwise required by law, the Series I Preferred Stock shall have no voting rights. In addition, as long as any shares of Series I
Preferred Stock are outstanding, the Corporation shall not, without the affirmative vote of the Holders of a majority of the then outstanding
shares of the Series I Preferred Stock, (a) alter or change adversely the powers, preferences or rights given to the Series I
Preferred Stock or alter or amend this Certificate of Designation or (b) enter into any agreement with respect to any of the foregoing.
Section 5. Liquidation Event.
Upon any liquidation, dissolution or winding-up of the Corporation, whether voluntary or involuntary (each, a “Liquidation Event”),
the Holders shall be entitled to receive out of the assets, whether capital or surplus, of the Corporation the same amount that a holder
of shares of the Common Stock would receive if the shares of Series I Preferred Stock were fully converted (disregarding for such
purposes any conversion limitations hereunder) to Common Stock, which amounts shall be paid pari passu with all holders of Common
Stock. The Corporation shall mail written notice of any such Liquidation Event, not less than thirty (30) days prior to the payment date
stated therein, to each Holder.
Section 6. Conversion.
(a) Conversions
at Option of Holder. Subject to Section 6 (Beneficial Ownership Limitation), each share of Series I Preferred
Stock shall be convertible, at any time and from time to time on or after the Original Issue Date, at the option of the Holder thereof,
into that number of shares of Common Stock determined by multiplying (i) the number of shares of Series I Preferred Stock to
be converted as set forth in the applicable Notice of Conversion (as defined below) by (ii) the Conversion Ratio. Holders shall effect
conversions by providing the Corporation with the form of conversion notice attached hereto as Annex A (a “Notice of Conversion”).
Each Notice of Conversion shall specify the number of shares of Series I Preferred Stock to be converted, the number of shares of
Series I Preferred Stock owned prior to the conversion at issue, the number of shares of Series I Preferred Stock owned subsequent
to the conversion at issue and the date on which such conversion is to be effected, which date may not be prior to the date the applicable
Holder delivers by facsimile or other method specified hereunder such Notice of Conversion to the Corporation (such date, the “Optional
Conversion Date”). If no Optional Conversion Date is specified in a Notice of Conversion, the Optional Conversion Date shall
be the date that such Notice of Conversion to the Corporation is deemed delivered hereunder. No ink-original Notice of Conversion shall
be required, nor shall any medallion guarantee (or other type of guarantee or notarization) of any Notice of Conversion form be required.
(b) Mandatory
Conversion. On the tenth (10) anniversary of the Original Issue Date (the “Mandatory Conversion Date” and
together with an Optional Conversion Date, the “Conversion Date”), each outstanding share of Series I Preferred
Stock will automatically convert (subject to the Beneficial Ownership Limitation set forth in Section 6) into such number
of fully paid and non-assessable shares of Common Stock as is determined by dividing the Stated Value by the Conversion Price in effect
on the Mandatory Conversion Date (a “Mandatory Conversion”). Within two Trading Days of the Mandatory Conversion Date,
the Corporation shall deliver to each Holder the Conversion Shares issuable upon conversion of such Holder’s Series I Preferred
Stock as of the Mandatory Conversion Date. To the extent that the Beneficial Ownership Limitation contained in Section 6 applies
to any Holder, such Holder shall within five Business Days of such Holder’s receipt of the Company Conversion Notice, provide the
Corporation with a written determination (a “Mandatory Conversion Determination”), of whether such Holder’s Series I
Preferred Stock is convertible (in relation to other securities owned by such Holder together with any Affiliates and Attribution Parties)
and of how many shares of Series I Preferred Stock are convertible, and the submission of a Mandatory Conversion Determination shall
be deemed to be such Holder’s determination of the maximum number of shares of Series I Preferred Stock that may be converted,
subject to the Beneficial Ownership Limitation and the portion of the shares of Common Stock issuable upon such Mandatory Conversion hereunder
that would cause such Holder to exceed the Beneficial Ownership Limitation shall be held by the Corporation in abeyance for the benefit
of such Holder (which shall not give the Holder any power to vote or dispose of such shares) until such time, if ever, as such Holder’s
beneficial ownership thereof would not result in such Holder exceeding the Beneficial Ownership Limitation. To ensure compliance with
this restriction, each Holder will be deemed to represent to the Corporation each time it delivers a Mandatory Conversion Determination
that such determination has not violated the restrictions set forth in Section 6 and the Corporation shall have no obligation
to verify or confirm the accuracy of such determination.
(c) Mechanics
of Conversion
(i) Delivery
of Conversion Shares Upon Conversion. Not later than the earlier of (i) two (2) Trading Days and (ii) the number of
Trading Days comprising the Standard Settlement Period (as defined below) after each Conversion Date (the “Share Delivery Date”),
the Corporation shall deliver, or cause to be delivered, to the converting Holder the Conversion Shares to be issued upon the conversion
of the number of shares of Series I Preferred Stock to be converted pursuant to Section 6 or 6, as applicable.
When delivering the Conversion Shares as provided herein, the Corporation shall use commercially reasonable efforts to deliver the Conversion
Shares required to be delivered by the Corporation under this Section 6 through the Transfer Agent. As used herein, “Standard
Settlement Period” means the standard settlement period, expressed in a number of Trading Days, on the Corporation’s primary
Trading Market with respect to the Common Stock as in effect on the date of delivery of the Notice of Conversion.
(ii) Failure
to Deliver Conversion Shares. If, in the case of any Notice of Conversion, such Conversion Shares are not delivered to or as directed
by the applicable Holder by the Share Delivery Date, the Holder shall be entitled to elect by written notice to the Corporation at any
time on or before its receipt of such Conversion Shares, to rescind such Conversion, in which event the Corporation shall promptly return
to the Holder the shares of Series I Preferred Stock that were the subject of such Notice of Conversion and the Holder shall promptly
return to the Corporation the Conversion Shares issued to such Holder pursuant to the rescinded Notice of Conversion.
(iii) Obligation
Absolute; Partial Liquidated Damages. The Corporation’s obligation to issue and deliver the Conversion Shares upon conversion
of Series I Preferred Stock in accordance with the terms hereof are absolute and unconditional, irrespective of any action or inaction
by a Holder to enforce the same, any waiver or consent with respect to any provision hereof, the recovery of any judgment against any
Person or any action to enforce the same, or any setoff, counterclaim, recoupment, limitation or termination, or any breach or alleged
breach by such Holder or any other Person of any obligation to the Corporation or any violation or alleged violation of law by such Holder
or any other person, and irrespective of any other circumstance which might otherwise limit such obligation of the Corporation to such
Holder in connection with the issuance of such Conversion Shares; provided, however, that such delivery shall not operate
as a waiver by the Corporation of any such action that the Corporation may have against such Holder. Nothing herein shall limit a Holder’s
right to pursue actual damages for the Corporation’s failure to deliver Conversion Shares within the period specified herein and
such Holder shall have the right to pursue all remedies available to it hereunder, at law or in equity including, without limitation,
a decree of specific performance, injunctive relief, or both specific performance and injunctive relief. The exercise of any such rights
shall not prohibit a Holder from seeking to enforce damages pursuant to any other Section hereof or under applicable law.
(iv) Compensation
for Buy-In on Failure to Timely Deliver Conversion Shares Upon Conversion. In addition to any other rights available to the Holder,
if the Corporation fails for any reason to deliver to a Holder the applicable Conversion Shares by the Share Delivery Date pursuant to
Section 6(c)(i), and if after such Share Delivery Date such Holder is required by its brokerage firm to purchase (in an open
market transaction or otherwise), or the Holder’s brokerage firm otherwise purchases, shares of Common Stock to deliver in satisfaction
of a sale by such Holder of the Conversion Shares which such Holder was entitled to receive upon the conversion relating to such Share
Delivery Date (a “Buy-In”), then the Corporation shall (A) pay in cash to such Holder (in addition to any other
remedies available to or elected by such Holder) the amount, if any, by which (x) such Holder’s total purchase price (including
any brokerage commissions) for the Common Stock so purchased exceeds (y) the product of (1) the aggregate number of shares of
Common Stock that such Holder was entitled to receive from the conversion at issue multiplied by (2) the actual sale price at which
the sell order giving rise to such purchase obligation was executed (including any brokerage commissions) and (B) at the option of
such Holder, either reissue (if surrendered) the shares of Series I Preferred Stock equal to the number of shares of Series I
Preferred Stock submitted for conversion (in which case, such conversion shall be deemed rescinded) or deliver to such Holder the number
of shares of Common Stock that would have been issued if the Corporation had timely complied with its delivery requirements under Section 6(c)(i).
For example, if a Holder purchases shares of Common Stock having a total purchase price of $11,000 to cover a Buy-In with respect to an
attempted conversion of shares of Series I Preferred Stock with respect to which the actual sale price of the Conversion Shares (including
any brokerage commissions) giving rise to such purchase obligation was a total of $10,000 under clause (A) of the immediately preceding
sentence, the Corporation shall be required to pay such Holder $1,000. The Holder shall provide the Corporation written notice indicating
the amounts payable to such Holder in respect of the Buy-In and, upon request of the Corporation, evidence of the amount of such loss.
Nothing herein shall limit a Holder’s right to pursue any other remedies available to it hereunder, at law or in equity including,
without limitation, a decree of specific performance and/or injunctive relief with respect to the Corporation’s failure to timely
deliver Conversion Shares upon conversion of the shares of Series I Preferred Stock as required pursuant to the terms hereof.
(v) Reservation
of Shares Issuable Upon Conversion. The Corporation covenants that it will at all times reserve and keep available out of its authorized
and unissued shares of Common Stock for the sole purpose of issuance upon conversion of the Series I Preferred Stock as herein provided,
free from preemptive rights or any other actual contingent purchase rights of Persons other than the Holder (and the other holders of
the Series I Preferred Stock), not less than such aggregate number of shares of the Common Stock as shall be issuable (taking into
account the adjustments and restrictions of Section 7) upon the conversion of the then outstanding shares of Series I
Preferred Stock. The Corporation covenants that all shares of Common Stock that shall be so issuable shall, upon issue, be duly authorized,
validly issued, fully paid and nonassessable.
(vi) Fractional
Shares. No fractional shares or scrip representing fractional shares shall be issued upon the conversion of the Series I Preferred
Stock. As to any fraction of a share which the Holder would otherwise be entitled to receive upon such conversion, the Corporation shall
at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the
fair market value of a share of Common Stock as determined in good faith by the Board of Directors of the Corporation, or round up to
the next whole share. Notwithstanding anything to the contrary contained herein, but consistent with the provisions of this subsection
with respect to fractional Conversion Shares, nothing shall prevent any Holder from converting fractional shares of Series I Preferred
Stock.
(vii) Transfer
Taxes and Expenses. The issuance of Conversion Shares on conversion of this Series I Preferred Stock shall be made without charge
to any Holder for any documentary stamp or similar taxes that may be payable in respect of the issue or delivery of such Conversion Shares,
provided that the Corporation shall not be required to pay any tax that may be payable in respect of any transfer involved in the issuance
and delivery of any such Conversion Shares upon conversion in a name other than that of the Holders of such shares of Series I Preferred
Stock and the Corporation shall not be required to issue or deliver such Conversion Shares unless or until the Person or Persons requesting
the issuance thereof shall have paid to the Corporation the amount of such tax or shall have established to the satisfaction of the Corporation
that such tax has been paid. The Corporation shall pay all Transfer Agent fees required for same-day processing of any Notice of Conversion
and all fees to the Depository Trust Company (or another established clearing corporation performing similar functions) required for same-day
electronic delivery of the Conversion Shares.
(d) Beneficial
Ownership Limitation. The Corporation shall not effect any conversion of the Series I Preferred Stock, including, without limitation,
a Mandatory Conversion, and a Holder shall not have the right to receive dividends hereunder or convert any portion of the Series I
Preferred Stock, to the extent that, after giving effect to the receipt of Dividend Shares hereunder or conversion set forth on the applicable
Notice of Conversion, to the extent that, after giving effect to the conversion set forth on the applicable Notice of Conversion, such
Holder (together with such Holder’s Affiliates, and any Persons acting as a group together with such Holder or any of such Holder’s
Affiliates (such Persons, “Attribution Parties”)) would beneficially own in excess of the Beneficial Ownership Limitation
(as defined below). For purposes of the foregoing sentence, the number of shares of Common Stock beneficially owned by such Holder and
its Affiliates and Attribution Parties shall include the number of shares of Common Stock received as Dividend Shares or issuable upon
conversion of the Series I Preferred Stock with respect to which such determination is being made, but shall exclude the number of
shares of Common Stock which are issuable upon (i) conversion of the remaining, unconverted Series I Preferred Stock beneficially
owned by such Holder or any of its Affiliates or Attribution Parties and (ii) exercise or conversion of the unexercised or unconverted
portion of any other securities of the Corporation subject to a limitation on conversion or exercise analogous to the limitation contained
herein beneficially owned by such Holder or any of its Affiliates or Attribution Parties. Except as set forth in the preceding sentence,
for purposes of this Section 6, beneficial ownership shall be calculated in accordance with Section 13(d) of the
Exchange Act and the rules and regulations promulgated thereunder. To the extent that the limitation contained in this Section 6
applies, the determination of whether the Series I Preferred Stock is convertible (in relation to other securities owned by such
Holder together with any Affiliates and Attribution Parties) and of how many shares of the Series I Preferred Stock are convertible
shall be in the sole discretion of such Holder, and the submission of a Notice of Conversion shall be deemed to be such Holder’s
determination of whether the shares of Series I Preferred Stock may be converted (in relation to other securities owned by such Holder
together with any Affiliates and Attribution Parties) and how many shares of the Series I Preferred Stock are convertible, in each
case subject to the Beneficial Ownership Limitation. To ensure compliance with this restriction, each Holder will be deemed to represent
to the Corporation each time it delivers a Notice of Conversion that such Notice of Conversion has not violated the restrictions set forth
in this paragraph and the Corporation shall have no obligation to verify or confirm the accuracy of such determination. In addition, a
determination as to any group status as contemplated above shall be determined in accordance with Section 13(d) of the Exchange
Act and the rules and regulations promulgated thereunder. For purposes of this Section 6, in determining the number of
outstanding shares of Common Stock, a Holder may rely on the number of outstanding shares of Common Stock as stated in the most recent
of the following: (i) the Corporation’s most recent periodic or annual report filed with the Commission, as the case may be,
(ii) a more recent public announcement by the Corporation or (iii) a more recent written notice by the Corporation or the Transfer
Agent setting forth the number of shares of Common Stock outstanding. Upon the written or oral request (which may be via email) of a Holder,
the Corporation shall within two Trading Days confirm orally and in writing to such Holder the number of shares of Common Stock then outstanding.
In any case, the number of outstanding shares of Common Stock shall be determined after giving effect to the conversion or exercise of
securities of the Corporation, including the Series I Preferred Stock, by such Holder or its Affiliates or Attribution Parties since
the date as of which such number of outstanding shares of Common Stock was reported. The “Beneficial Ownership Limitation”
shall be 9.99% of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance of shares of Common
Stock issuable upon conversion of the Series I Preferred Stock held by the applicable Holder. A Holder, upon notice to the Corporation,
may increase or decrease the Beneficial Ownership Limitation provisions of this Section 6 applicable to its Series I
Preferred Stock provided that the Beneficial Ownership Limitation in no event exceeds 9.99% of the number of shares of the Common Stock
outstanding immediately after giving effect to the issuance of shares of Common Stock upon conversion of the Series I Preferred Stock
held by the Holder and the provisions of this Section 6 shall continue to apply. Any such increase in the Beneficial Ownership
Limitation will not be effective until the 61st day after such notice is delivered to the Corporation and shall only apply to such Holder
and no other Holder. The provisions of this paragraph shall be construed and implemented in a manner otherwise than in strict conformity
with the terms of this Section 6 to correct this paragraph (or any portion hereof) which may be defective or inconsistent
with the intended Beneficial Ownership Limitation contained herein or to make changes or supplements necessary or desirable to properly
give effect to such limitation. The limitations contained in this paragraph shall apply to a successor holder of the Series I Preferred
Stock.
Section 7. Certain Adjustments.
(a) Stock
Dividends and Stock Splits. If the Corporation, at any time while this Series I Preferred Stock is outstanding: (i) pays
a stock dividend or otherwise makes a distribution or distributions payable in shares of Common Stock on shares of Common Stock or any
other Common Stock Equivalents (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Corporation
upon conversion of, or payment of a dividend on, this Series I Preferred Stock), (ii) subdivides outstanding shares of Common
Stock into a larger number of shares, (iii) combines (including by way of a reverse stock split) outstanding shares of Common Stock
into a smaller number of shares, or (iv) issues, in the event of a reclassification of shares of the Common Stock, any shares of
capital stock of the Corporation, then the Conversion Price shall be multiplied by a fraction of which the numerator shall be the number
of shares of Common Stock (excluding any treasury shares of the Corporation) outstanding immediately before such event, and of which the
denominator shall be the number of shares of Common Stock outstanding immediately after such event. Any adjustment made pursuant to this
Section 7(a) shall become effective immediately after the record date for the determination of stockholders entitled
to receive such dividend or distribution and shall become effective immediately after the effective date in the case of a subdivision,
combination or re-classification.
(b) Subsequent
Rights Offerings. In addition to any adjustments pursuant to Section 7(a) above, if at any time the Corporation grants,
issues or sells any Common Stock Equivalents or rights to purchase stock, warrants, securities or other property pro rata to the record
holders of shares of Common Stock (the “Purchase Rights”), then the Holder will be entitled to acquire, upon the terms
applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had held the number
of shares of Common Stock acquirable upon complete conversion of such Holder’s Series I Preferred Stock (without regard to
any limitations on conversion hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date on
which a record is taken for the grant, issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which
the record holders of shares of Common Stock are to be determined for the grant, issue or sale of such Purchase Rights (provided, however,
to the extent that the Holder’s right to participate in any such Purchase Right would result in the Holder exceeding the Beneficial
Ownership Limitation, then the Holder shall not be entitled to participate in such Purchase Right to such extent (or beneficial ownership
of such shares of Common Stock as a result of such Purchase Right to such extent) and such Purchase Right to such extent shall be held
in abeyance for the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership
Limitation).
(c) Pro
Rata Distributions. During such time as this Series I Preferred Stock is outstanding, if the Corporation declares or makes any
dividend or other distribution of its assets (or rights to acquire its assets) to holders of shares of Common Stock, by way of return
of capital or otherwise (including, without limitation, any distribution of cash, stock or other securities, property or options by way
of a dividend, spin off, reclassification, corporate rearrangement, scheme of arrangement or other similar transaction) (a “Distribution”),
at any time after the issuance of this Series I Preferred Stock, then, in each such case, the Holder shall be entitled to participate
in such Distribution to the same extent that the Holder would have participated therein if the Holder had held the number of shares of
Common Stock acquirable upon complete conversion of this Series I Preferred Stock (without regard to any limitations on conversion
hereof, including without limitation, the Beneficial Ownership Limitation) immediately before the date of which a record is taken for
such Distribution, or, if no such record is taken, the date as of which the record holders of shares of Common Stock are to be determined
for the participation in such Distribution (provided, however, to the extent that the Holder’s right to participate
in any such Distribution would result in the Holder exceeding the Beneficial Ownership Limitation, then the Holder shall not be entitled
to participate in such Distribution to such extent (or in the beneficial ownership of any shares of Common Stock as a result of such Distribution
to such extent) and the portion of such Distribution shall be held in abeyance for the benefit of the Holder until such time, if ever,
as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation).
(d) Fundamental
Transaction. If, at any time while this Series I Preferred Stock is outstanding, (i) the Corporation, directly or indirectly,
in one or more related transactions effects any merger or consolidation of the Corporation with or into another Person and the Corporation
is not the surviving Person, (ii) the Corporation, directly or indirectly, effects any sale, lease, license, assignment, transfer,
conveyance or other disposition of all or substantially all of its assets in one or a series of related transactions, (iii) any direct
or indirect purchase offer, tender offer or exchange offer is completed pursuant to which holders of Common Stock are permitted to sell,
tender or exchange their shares for other securities, cash or property and has been accepted by the holders of 50% or more of the outstanding
Common Stock, (iv) the Corporation, directly or indirectly, in one or more related transactions effects any reclassification, reorganization
or recapitalization of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively converted into
or exchanged for other securities, cash or property, or (v) the Corporation, directly or indirectly, in one or more related transactions
consummates a stock or share purchase agreement or other business combination (including, without limitation, a reorganization, recapitalization,
spin-off or scheme of arrangement) with another Person whereby such other Person acquires more than 50% of the outstanding shares of Common
Stock (each a “Fundamental Transaction”), then, immediately prior but subject to the occurrence of the Fundamental
Transaction each outstanding share of Series I Preferred Stock shall automatically convert into shares of Common Stock, without any
action of or by the Holders or the Corporation, at the Conversion Ratio then in effect, and the Holders shall receive, for each Conversion
Share, such consideration, at the same time and subject to the same terms and conditions, as the other holders of Common Stock pursuant
to the terms of the Fundamental Transaction; provided, however, that such conversion would not result in the Holder exceeding
the Beneficial Ownership Limitation in the successor entity, or if no successor entity, the Corporation. If holders of Common Stock are
given any choice as to the securities, cash or property to be received in a Fundamental Transaction, then the Holders shall be given the
same choice.
(e) Calculations.
All calculations under this Section 7 shall be made to the nearest cent or the nearest 1/100th of a share, as the case may
be. For purposes of this Section 7, the number of shares of Common Stock deemed to be issued and outstanding as of a given
date shall be the sum of the number of shares of Common Stock (excluding any treasury shares of the Corporation) issued and outstanding.
(f) Notice
to the Holders.
(i) Adjustment
to Conversion Price. Whenever the Conversion Price is adjusted pursuant to any provision of this Section 7, the Corporation
shall promptly deliver to each record Holder by facsimile or email a notice setting forth the Conversion Price after such adjustment and
setting forth a brief statement of the facts requiring such adjustment.
(ii) Notice
to Allow Conversion by Holder. If (A) the Corporation shall declare a dividend (or any other distribution in whatever form) on
the Common Stock, (B) the Corporation shall declare a special nonrecurring cash dividend on or a redemption of the Common Stock applicable
to all holders of Common Stock, (C) the Corporation shall authorize the granting to all holders of the Common Stock of rights or
warrants to subscribe for or purchase any shares of capital stock of any class or of any rights, (D) the approval of any stockholders
of the Corporation shall be required in connection with any reclassification of the Common Stock, any consolidation or merger to which
the Corporation is a party, any sale or transfer of all or substantially all of the assets of the Corporation, or any compulsory share
exchange whereby the Common Stock is converted into other securities, cash or property, or (E) the Corporation shall authorize the
voluntary or involuntary dissolution, liquidation or winding up of the affairs of the Corporation, then, in each case, the Corporation
shall cause to be filed at each office or agency maintained for the purpose of conversion of this Series I Preferred Stock, and shall
cause to be delivered by facsimile or email to each record Holder at its last facsimile number or email address as it shall appear upon
the stock books of the Corporation, at least twenty (20) calendar days prior to the applicable record or effective date hereinafter specified,
a notice stating (x) the date on which a record is to be taken for the purpose of such dividend, distribution, redemption, rights
or warrants, or if a record is not to be taken, the date as of which the holders of the Common Stock of record to be entitled to such
dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on which such reclassification, consolidation,
merger, sale, transfer or share exchange is expected to become effective or close, and the date as of which it is expected that holders
of the Common Stock of record shall be entitled to exchange their shares of the Common Stock for securities, cash or other property deliverable
upon such reclassification, consolidation, merger, sale, transfer or share exchange, provided that the failure to deliver such notice
or any defect therein or in the delivery thereof shall not affect the validity of the corporate action required to be specified in such
notice. To the extent that any notice provided hereunder constitutes, or contains, material, non-public information regarding the Corporation
or any of the Subsidiaries, the Corporation shall simultaneously file such notice with the Commission pursuant to a Current Report on
Form 8-K. The Holder shall remain entitled to convert part or all of the shares of Series I Preferred Stock held by such Holder
during the 20-day period commencing on the date of such notice through the effective date of the event triggering such notice except as
may otherwise be expressly set forth herein.
Section 8. Miscellaneous.
(a) Notices.
Any and all notices or other communications or deliveries to be provided by the Holders hereunder shall be in writing and delivered personally,
by facsimile, by e-mail or sent by a nationally recognized overnight courier service, addressed to the Corporation, at the address set
forth above Attention: Chief Executive Officer, facsimile number (415) 371-8311, email: lconte@jaguar.health with a copy sent to attention
of the Corporation’s Chief Financial Officer, facsimile number (415) 371-8311, email: clizak@jaguar.health or such other facsimile
number or address as the Corporation may specify for such purposes by notice to the Holders delivered in accordance with this Section 8(a).
Any and all notices or other communications or deliveries to be provided by the Corporation hereunder shall be in writing and delivered
personally, by facsimile, by e-mail or sent by a nationally recognized overnight courier service addressed to each record Holder at the
facsimile number, e-mail address or address of such Holder appearing on the books of the Corporation. Any notice or other communication
or deliveries hereunder shall be deemed given and effective on the earliest of (i) the time of transmission, if such notice or communication
is delivered via facsimile or e-mail at the facsimile number or e-mail address set forth in this Section 8(a) prior to
5:30 p.m. (New York City time) on any Trading Day, (ii) the next Trading Day after the time of transmission, if such notice
or communication is delivered via facsimile or via e-mail at the facsimile number or e-mail address set forth in this Section 8(a) on
a day that is not a Trading Day or later than 5:30 p.m. (New York City time) on any Trading Day, (iii) the second Trading Day
following the date of mailing, if sent by U.S. nationally recognized overnight courier service, or (iv) upon actual receipt by the
party to whom such notice is required to be given.
(b) Governing
Law. All questions concerning the construction, validity, enforcement and interpretation of this Certificate of Designation shall
be governed by and construed and enforced in accordance with the internal laws of the State of Delaware, without regard to the principles
of conflict of laws thereof. The rule of construction to the effect that any ambiguities are to be resolved against the drafting
party shall not be employed in the interpretation of this Certificate of Designation or any amendments thereto. All legal proceedings
concerning the interpretation, enforcement and defense of the transactions contemplated by this Certificate of Designation (whether brought
against a party hereto or its respective Affiliates, directors, officers, shareholders, employees or agents) shall be commenced in the
state and federal courts sitting in the State of Delaware, (the “Delaware Courts”).
(c) Uncertificated
Shares. The shares of Series I Preferred Stock shall be uncertificated.
(d) Waiver.
Any waiver by the Corporation or a Holder of a breach of any provision of this Certificate of Designation shall not operate as or be construed
to be a waiver of any other breach of such provision or of any breach of any other provision of this Certificate of Designation or a waiver
by any other Holders. The failure of the Corporation or a Holder to insist upon strict adherence to any term of this Certificate of Designation
on one or more occasions shall not be considered a waiver or deprive that party (or any other Holder) of the right thereafter to insist
upon strict adherence to that term or any other term of this Certificate of Designation on any other occasion. Any waiver by the Corporation
or a Holder must be in writing.
(e) Severability.
If any provision of this Certificate of Designation is invalid, illegal or unenforceable, the balance of this Certificate of Designation
shall remain in effect, and if any provision is inapplicable to any Person or circumstance, it shall nevertheless remain applicable to
all other Persons and circumstances. If it shall be found that any interest or other amount deemed interest due hereunder violates the
applicable law governing usury, the applicable rate of interest due hereunder shall automatically be lowered to equal the maximum rate
of interest permitted under applicable law.
(f) Next
Business Day. Whenever any payment or other obligation hereunder shall be due on a day other than a Business Day, such payment shall
be made or other obligation performed on the next succeeding Business Day.
(g) Headings.
The headings contained herein are for convenience only, do not constitute a part of this Certificate of Designation and shall not be deemed
to limit or affect any of the provisions hereof.
(h) Status
of Converted or Redeemed Preferred Stock. Any shares of Series I Preferred Stock that are converted, redeemed or otherwise acquired
by the Corporation or any of its subsidiaries in accordance with the terms of this Certificate of Designation shall be automatically and
immediately cancelled and retired and shall not be reissued, sold or transfer as shares of Series I Preferred Stock, and shall resume
the status of authorized but unissued shares of preferred stock and the Corporation may thereafter take such appropriate action (without
the need for stockholder action) as may be necessary to reduce the authorized number of shares of Series I Preferred Stock accordingly.
(i) Amendment.
In addition to any other vote or consent required by the Certificate of Incorporation (including this Certificate of Designation) or required
by law, any of the provisions, terms, rights, powers, preferences and other terms of the Series I Preferred Stock set forth herein
may be amended or waived on behalf of all Holders of Series I Preferred Stock by the affirmative written consent or vote of the Holders
of at least a majority of the shares of Series I Preferred Stock then outstanding.
*********************
RESOLVED, FURTHER, that the
chief executive officer, the president, the chief financial officer or any vice-president, and the secretary or any assistant secretary,
of the Corporation be and they hereby are authorized and directed to prepare and file this Certificate of Designation of Preferences,
Rights and Limitations in accordance with the foregoing resolution and the provisions of Delaware law.
IN WITNESS WHEREOF, the undersigned have executed
this Certificate this 29th day of September, 2023.
/s/ Lisa A. Conte |
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/s/ Carol R. Lizak |
Name: Lisa A. Conte |
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Name: Carol R. Lizak |
Title: Chief Executive Officer and President |
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Title: Chief Financial Officer |
ANNEX A
NOTICE OF CONVERSION
(TO BE EXECUTED BY THE REGISTERED HOLDER IN ORDER
TO CONVERT SHARES OF PREFERRED STOCK)
The undersigned hereby elects to convert the number
of shares of Series I Convertible Preferred Stock (the “Preferred Stock”) indicated below into shares of common
stock, par value $0.0001 per share (the “Common Stock”), of Jaguar Health, Inc., a Delaware corporation (the “Corporation”),
according to the conditions hereof, as of the date written below. If shares of Common Stock are to be issued in the name of a Person other
than the undersigned, the undersigned will pay all transfer taxes payable with respect thereto. No fee will be charged to the undersigned
for any conversion, except for any such transfer taxes.
Conversion calculations:
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Date to Effect Conversion: |
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Number of shares of Preferred Stock owned prior to Conversion: |
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Number of shares of Preferred Stock to be Converted: |
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Stated Value of shares of Preferred Stock to be Converted: |
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Number of shares of Common Stock to be Issued: |
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Applicable Conversion Price: |
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Number of shares of Preferred Stock subsequent to Conversion: |
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Address for Delivery: |
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or |
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DWAC Instructions: |
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Broker no: |
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Account no: |
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[HOLDER] |
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By: |
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Name: |
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Title: |
Exhibit 4.1
GLOBAL AMENDMENT #2
This Global Amendment No. 2
(this “Amendment”) is entered into as of September 29, 2023 by and between Iliad Research and Trading, L.P., a
Utah limited partnership (“Investor”), and Jaguar Health, Inc. a Delaware corporation (“Company”).
Capitalized terms used in this Amendment without definition shall have the meanings given to them in the Royalty Interest (as defined
below).
A. Company
previously sold and issued to Investor that certain Royalty Interest dated October 8, 2020 in the original principal amount of $12,000,000,
which was amended pursuant to the Global Amendment, dated April 14, 2022, between the Company and Investor (the “Royalty
Interest”).
B. Investor
and Company have agreed, subject to the terms, amendments, conditions and understandings expressed in this Amendment, to amend the Royalty
Interest as set forth herein.
NOW, THEREFORE, for good and
valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows:
1. Recitals.
Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Amendment are true and accurate and are hereby
incorporated into and made a part of this Amendment.
2. Amendment.
Section 2.2 of the Royalty Interest is hereby deleted and replaced in its entirety with the following provision:
“2.2 Minimum
Royalty Payment. Beginning on January 1, 2026, the monthly Royalty Payment shall be the greater of (a) $750,000.00, and
(b) the actual Royalty Payment amount Investor is entitled to for such month pursuant to Section 2.1 above.”
3. Warrant.
In consideration for the accommodations granted pursuant to this Amendment, Company agrees to issue a warrant to purchase 232,500 shares
of the Company’s common stock, par value $0.0001 per share (the “Common Stock Purchase Warrant”), to Investor
in substantially the form attached hereto as Exhibit A.
4. Representations
and Warranties. In order to induce Investor to enter into this Amendment, Company, for itself, and for its affiliates, successors
and assigns, hereby acknowledges, represents, warrants and agrees as follows:
(a) Company
has full power and authority to enter into this Amendment and to incur and perform all obligations and covenants contained herein, all
of which have been duly authorized by all proper and necessary action. No consent, approval, filing or registration with or notice to
any governmental authority is required as a condition to the validity of this Amendment or the performance of any of the obligations of
Company hereunder.
(b) There
is no fact known to Company or which should be known to Company which Company has not disclosed to Investor on or prior to the date of
this Amendment which would or could materially and adversely affect the understanding of Investor expressed in this Amendment or any representation,
warranty, or recital contained in this Amendment.
(c) Except
as expressly set forth in this Amendment, Company acknowledges and agrees that neither the execution and delivery of this Amendment nor
any of the terms, provisions, covenants, or agreements contained in this Amendment shall in any manner release, impair, lessen, modify,
waive, or otherwise affect the liability and obligations of Company under the terms of the Royalty Interest.
(d) Company
has no defenses, affirmative or otherwise, rights of setoff, rights of recoupment, claims, counterclaims, actions or causes of action
of any kind or nature whatsoever against Investor, directly or indirectly, arising out of, based upon, or in any manner connected with,
the transactions contemplated hereby, whether known or unknown, which occurred, existed, was taken, permitted, or begun prior to the execution
of this Amendment and occurred, existed, was taken, permitted or begun in accordance with, pursuant to, or by virtue of any of the terms
or conditions of the Royalty Interest. To the extent any such defenses, affirmative or otherwise, rights of setoff, rights of recoupment,
claims, counterclaims, actions or causes of action exist or existed, such defenses, rights, claims, counterclaims, actions and causes
of action are hereby waived, discharged and released. Company hereby acknowledges and agrees that the execution of this Amendment by Investor
shall not constitute an acknowledgment of or admission by Investor of the existence of any claims or of liability for any matter or precedent
upon which any claim or liability may be asserted.
(e) Company
represents and warrants that as of the date hereof no Events of Default or other material breaches exist under the Royalty Interest, or
have occurred prior to the date hereof.
5. Other
Terms Unchanged. The Royalty Interest, as amended by this Amendment, remains and continues in full force and effect, constitutes legal,
valid, and binding obligations of each of the parties, and is in all respects agreed to, ratified, and confirmed. Any reference to the
Royalty Interest after the date of this Amendment is deemed to be a reference to the Royalty Interest as amended by this Amendment. If
there is a conflict between the terms of this Amendment and the Royalty Interest, the terms of this Amendment shall control. No forbearance
or waiver may be implied by this Amendment. Company acknowledges that it is unconditionally obligated to pay the remaining balance of
the Royalty Interest and represents that such obligation is not subject to any deductions, defenses, rights of offset, or counterclaims
of any kind. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver
of, or as an amendment to, any right, power, or remedy of Investor under the Royalty Interest, as in effect prior to the date hereof.
6. No
Reliance. Company acknowledges and agrees that neither Investor nor any of its officers, directors, members, managers, equity holders,
representatives or agents has made any representations or warranties to Company or any of its agents, representatives, officers, directors,
or employees except as expressly set forth in this Amendment and the Royalty Interest and, in making its decision to enter into the transactions
contemplated by this Amendment, Company is not relying on any representation, warranty, covenant or promise of Investor or its officers,
directors, members, managers, equity holders, agents or representatives other than as set forth in this Amendment.
7. Counterparts.
This Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall
constitute one instrument. The parties hereto confirm that any electronic copy of another party’s executed counterpart of this Amendment
(or such party’s signature page thereof) will be deemed to be an executed original thereof.
8. Further
Assurances. Each party shall do and perform or cause to be done and performed, all such further acts and things, and shall execute
and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to
carry out the intent and accomplish the purposes of this Amendment and the consummation of the transactions contemplated hereby.
[Remainder of page intentionally left blank]
IN WITNESS WHEREOF, the undersigned have executed
this Amendment as of the date set forth above.
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COMPANY: |
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JAGUAR HEALTH, Inc. |
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By: |
/s/ Lisa Conte |
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Lisa Conte, President and CEO |
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INVESTOR: |
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ILIAD RESEARCH AND TRADING, L.P. |
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By: Iliad Management, LLC, its General Partner |
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By: Fife Trading, Inc., its Manager |
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By: |
/s/ John M. Fife |
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John M. Fife, President |
EXHIBITS:
Exhibit A Warrant
[Signature Page to Global
Amendment #2]
Exhibit 4.2
GLOBAL AMENDMENT #2
This Global Amendment No. 2
(this “Amendment”) is entered into as of September 29, 2023 by and between Uptown Capital, LLC, a Utah limited
liability company (f/k/a Irving Park Capital, LLC) (“Investor”), and Jaguar Health, Inc. a Delaware corporation
(“Company”). Capitalized terms used in this Amendment without definition shall have the meanings given to them in the
Royalty Interest (as defined below).
A. Company
previously sold and issued to Investor that certain Royalty Interest dated December 22, 2020 in the original principal amount of
$12,000,000, which was amended pursuant to the Global Amendment, dated April 14, 2022, between the Company and Investor (the “Royalty
Interest”).
B. Investor
and Company have agreed, subject to the terms, amendments, conditions and understandings expressed in this Amendment, to amend the Royalty
Interest as set forth herein.
NOW, THEREFORE, for good and
valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows:
1. Recitals.
Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Amendment are true and accurate and are hereby
incorporated into and made a part of this Amendment.
2. Amendment.
Section 2.2 of the Royalty Interest is hereby deleted and replaced in its entirety with the following provision:
“2.2 Minimum
Royalty Payment. Beginning on January 1, 2026, the monthly Royalty Payment shall be the greater of (a) $750,000.00, and
(b) the actual Royalty Payment amount Investor is entitled to for such month pursuant to Section 2.1 above.”
3. Warrant.
In consideration for the accommodations granted pursuant to this Amendment, Company agrees to issue a warrant to purchase 262,500 shares
of the Company’s common stock, par value $0.0001 per share (the “Common Stock Purchase Warrant”), to Investor
in substantially the form attached hereto as Exhibit A.
4. Representations
and Warranties. In order to induce Investor to enter into this Amendment, Company, for itself, and for its affiliates, successors
and assigns, hereby acknowledges, represents, warrants and agrees as follows:
(a) Company
has full power and authority to enter into this Amendment and to incur and perform all obligations and covenants contained herein, all
of which have been duly authorized by all proper and necessary action. No consent, approval, filing or registration with or notice to
any governmental authority is required as a condition to the validity of this Amendment or the performance of any of the obligations of
Company hereunder.
(b) There
is no fact known to Company or which should be known to Company which Company has not disclosed to Investor on or prior to the date of
this Amendment which would or could materially and adversely affect the understanding of Investor expressed in this Amendment or any representation,
warranty, or recital contained in this Amendment.
(c) Except
as expressly set forth in this Amendment, Company acknowledges and agrees that neither the execution and delivery of this Amendment nor
any of the terms, provisions, covenants, or agreements contained in this Amendment shall in any manner release, impair, lessen, modify,
waive, or otherwise affect the liability and obligations of Company under the terms of the Royalty Interest.
(d) Company
has no defenses, affirmative or otherwise, rights of setoff, rights of recoupment, claims, counterclaims, actions or causes of action
of any kind or nature whatsoever against Investor, directly or indirectly, arising out of, based upon, or in any manner connected with,
the transactions contemplated hereby, whether known or unknown, which occurred, existed, was taken, permitted, or begun prior to the execution
of this Amendment and occurred, existed, was taken, permitted or begun in accordance with, pursuant to, or by virtue of any of the terms
or conditions of the Royalty Interest. To the extent any such defenses, affirmative or otherwise, rights of setoff, rights of recoupment,
claims, counterclaims, actions or causes of action exist or existed, such defenses, rights, claims, counterclaims, actions and causes
of action are hereby waived, discharged and released. Company hereby acknowledges and agrees that the execution of this Amendment by Investor
shall not constitute an acknowledgment of or admission by Investor of the existence of any claims or of liability for any matter or precedent
upon which any claim or liability may be asserted.
(e) Company
represents and warrants that as of the date hereof no Events of Default or other material breaches exist under the Royalty Interest, or
have occurred prior to the date hereof.
5. Other
Terms Unchanged. The Royalty Interest, as amended by this Amendment, remains and continues in full force and effect, constitutes legal,
valid, and binding obligations of each of the parties, and is in all respects agreed to, ratified, and confirmed. Any reference to the
Royalty Interest after the date of this Amendment is deemed to be a reference to the Royalty Interest as amended by this Amendment. If
there is a conflict between the terms of this Amendment and the Royalty Interest, the terms of this Amendment shall control. No forbearance
or waiver may be implied by this Amendment. Company acknowledges that it is unconditionally obligated to pay the remaining balance of
the Royalty Interest and represents that such obligation is not subject to any deductions, defenses, rights of offset, or counterclaims
of any kind. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver
of, or as an amendment to, any right, power, or remedy of Investor under the Royalty Interest, as in effect prior to the date hereof.
6. No
Reliance. Company acknowledges and agrees that neither Investor nor any of its officers, directors, members, managers, equity holders,
representatives or agents has made any representations or warranties to Company or any of its agents, representatives, officers, directors,
or employees except as expressly set forth in this Amendment and the Royalty Interest and, in making its decision to enter into the transactions
contemplated by this Amendment, Company is not relying on any representation, warranty, covenant or promise of Investor or its officers,
directors, members, managers, equity holders, agents or representatives other than as set forth in this Amendment.
7. Counterparts.
This Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall
constitute one instrument. The parties hereto confirm that any electronic copy of another party’s executed counterpart of this Amendment
(or such party’s signature page thereof) will be deemed to be an executed original thereof.
8.
Further Assurances. Each party shall do and perform or cause
to be done and performed, all such further acts and things, and shall execute and deliver all such other agreements, certificates,
instruments and documents, as the other party may reasonably request in order to carry out the intent and accomplish the purposes of
this Amendment and the consummation of the transactions contemplated hereby.
[Remainder of page intentionally left blank]
IN WITNESS WHEREOF, the undersigned have executed
this Amendment as of the date set forth above.
|
COMPANY: |
|
|
|
JAGUAR
HEALTH, Inc. |
|
|
|
By: |
/s/ Lisa Conte |
|
|
Lisa Conte, President and CEO |
|
INVESTOR: |
|
|
|
UPTOWN CAPITAL, LLC |
|
|
|
By: |
/s/ John M. Fife |
|
|
John M. Fife, President |
EXHIBITS:
Exhibit A Warrant
[Signature Page to Global
Amendment #2]
Exhibit 4.3
GLOBAL AMENDMENT #1
This Global Amendment No. 1
(this “Amendment”) is entered into as of September 29, 2023 by and between Streeterville Capital, LLC, a Utah
limited liability company (“Investor”), and Jaguar Health, Inc. a Delaware corporation (“Company”).
Capitalized terms used in this Amendment without definition shall have the meanings given to them in the Royalty Interest (as defined
below).
A. Company
previously sold and issued to Investor that certain Royalty Interest dated August 24, 2022 in the original principal amount of $12,000,000
between the Company and Investor (the “Royalty Interest”).
B. Investor
and Company have agreed, subject to the terms, amendments, conditions and understandings expressed in this Amendment, to amend the Royalty
Interest as set forth herein.
NOW, THEREFORE, for good and
valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows:
1. Recitals.
Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Amendment are true and accurate and are hereby
incorporated into and made a part of this Amendment.
2. Prepayment.
Section 1.2 of the Royalty Interest is hereby deleted in its entirety and replaced in its entirety with the following provision:
“1.2 [INTENTIONALLY
DELETED]”
3. Representations
and Warranties. In order to induce Investor to enter into this Amendment, Company, for itself, and for its affiliates, successors
and assigns, hereby acknowledges, represents, warrants and agrees as follows:
(a) Company
has full power and authority to enter into this Amendment and to incur and perform all obligations and covenants contained herein, all
of which have been duly authorized by all proper and necessary action. No consent, approval, filing or registration with or notice to
any governmental authority is required as a condition to the validity of this Amendment or the performance of any of the obligations of
Company hereunder.
(b) There
is no fact known to Company or which should be known to Company which Company has not disclosed to Investor on or prior to the date of
this Amendment which would or could materially and adversely affect the understanding of Investor expressed in this Amendment or any representation,
warranty, or recital contained in this Amendment.
(c) Except
as expressly set forth in this Amendment, Company acknowledges and agrees that neither the execution and delivery of this Amendment nor
any of the terms, provisions, covenants, or agreements contained in this Amendment shall in any manner release, impair, lessen, modify,
waive, or otherwise affect the liability and obligations of Company under the terms of the Royalty Interest.
(d) Company
has no defenses, affirmative or otherwise, rights of setoff, rights of recoupment, claims, counterclaims, actions or causes of action
of any kind or nature whatsoever against Investor, directly or indirectly, arising out of, based upon, or in any manner connected with,
the transactions contemplated hereby, whether known or unknown, which occurred, existed, was taken, permitted, or begun prior to the execution
of this Amendment and occurred, existed, was taken, permitted or begun in accordance with, pursuant to, or by virtue of any of the terms
or conditions of the Royalty Interest. To the extent any such defenses, affirmative or otherwise, rights of setoff, rights of recoupment,
claims, counterclaims, actions or causes of action exist or existed, such defenses, rights, claims, counterclaims, actions and causes
of action are hereby waived, discharged and released. Company hereby acknowledges and agrees that the execution of this Amendment by Investor
shall not constitute an acknowledgment of or admission by Investor of the existence of any claims or of liability for any matter or precedent
upon which any claim or liability may be asserted.
(e) Company
represents and warrants that as of the date hereof no Events of Default or other material breaches exist under the Royalty Interest, or
have occurred prior to the date hereof.
4. Other
Terms Unchanged. The Royalty Interest, as amended by this Amendment, remains and continues in full force and effect, constitutes legal,
valid, and binding obligations of each of the parties, and is in all respects agreed to, ratified, and confirmed. Any reference to the
Royalty Interest after the date of this Amendment is deemed to be a reference to the Royalty Interest as amended by this Amendment. If
there is a conflict between the terms of this Amendment and the Royalty Interest, the terms of this Amendment shall control. No forbearance
or waiver may be implied by this Amendment. Company acknowledges that it is unconditionally obligated to pay the remaining balance of
the Royalty Interest and represents that such obligation is not subject to any deductions, defenses, rights of offset, or counterclaims
of any kind. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver
of, or as an amendment to, any right, power, or remedy of Investor under the Royalty Interest, as in effect prior to the date hereof.
5. No
Reliance. Company acknowledges and agrees that neither Investor nor any of its officers, directors, members, managers, equity holders,
representatives or agents has made any representations or warranties to Company or any of its agents, representatives, officers, directors,
or employees except as expressly set forth in this Amendment and the Royalty Interest and, in making its decision to enter into the transactions
contemplated by this Amendment, Company is not relying on any representation, warranty, covenant or promise of Investor or its officers,
directors, members, managers, equity holders, agents or representatives other than as set forth in this Amendment.
6. Counterparts.
This Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall
constitute one instrument. The parties hereto confirm that any electronic copy of another party’s executed counterpart of this Amendment
(or such party’s signature page thereof) will be deemed to be an executed original thereof.
7. Further
Assurances. Each party shall do and perform or cause to be done and performed, all such further acts and things, and shall execute
and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to
carry out the intent and accomplish the purposes of this Amendment and the consummation of the transactions contemplated hereby.
[Remainder of page intentionally left blank]
IN WITNESS WHEREOF, the undersigned have executed
this Amendment as of the date set forth above.
|
COMPANY: |
|
|
|
JAGUAR
HEALTH, Inc. |
|
|
|
By: |
/s/ Lisa Conte |
|
|
Lisa Conte, President and CEO |
|
INVESTOR: |
|
|
|
STREETERVILLE CAPITAL, LLC |
|
|
|
By: |
/s/ John M. Fife |
|
|
John M. Fife, President |
[Signature Page to Global
Amendment]
Exhibit 4.4
GLOBAL AMENDMENT #2
This Global Amendment No. 2
(this “Amendment”) is entered into as of September 29, 2023 by and between Streeterville Capital, LLC, a Utah
limited liability company (“Investor”), and Jaguar Health, Inc. a Delaware corporation (“Company”).
Capitalized terms used in this Amendment without definition shall have the meanings given to them in the Royalty Interest (as defined
below).
A. Company
previously sold and issued to Investor that certain Royalty Interest dated August 24, 2022 in the original principal amount of $12,000,000,
which was amended pursuant to the Global Amendment, dated September 29, 2023, between the Company and Investor (the “Royalty
Interest”).
B. Investor
and Company have agreed, subject to the terms, amendments, conditions and understandings expressed in this Amendment, to amend the Royalty
Interest as set forth herein.
NOW, THEREFORE, for good and
valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows:
1. Recitals.
Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Amendment are true and accurate and are hereby
incorporated into and made a part of this Amendment.
2. Amendment.
Section 2.2 of the Royalty Interest is hereby deleted and replaced in its entirety with the following provision:
“2.2 Minimum
Royalty Payment. Beginning on January 1, 2026, the monthly Royalty Payment shall be the greater of (a) $750,000.00, and
(b) the actual Royalty Payment amount Investor is entitled to for such month pursuant to Section 2.1 above.”
3. Warrant.
In consideration for the accommodations granted pursuant to this Amendment, Company agrees to issue a warrant to purchase 255,000 shares
of the Company’s common stock, par value $0.0001 per share (the “Common Stock Purchase Warrant”), to Investor
in substantially the form attached hereto as Exhibit A.
4. Representations
and Warranties. In order to induce Investor to enter into this Amendment, Company, for itself, and for its affiliates, successors
and assigns, hereby acknowledges, represents, warrants and agrees as follows:
(a) Company
has full power and authority to enter into this Amendment and to incur and perform all obligations and covenants contained herein, all
of which have been duly authorized by all proper and necessary action. No consent, approval, filing or registration with or notice to
any governmental authority is required as a condition to the validity of this Amendment or the performance of any of the obligations of
Company hereunder.
(b) There
is no fact known to Company or which should be known to Company which Company has not disclosed to Investor on or prior to the date of
this Amendment which would or could materially and adversely affect the understanding of Investor expressed in this Amendment or any representation,
warranty, or recital contained in this Amendment.
(c) Except
as expressly set forth in this Amendment, Company acknowledges and agrees that neither the execution and delivery of this Amendment nor
any of the terms, provisions, covenants, or agreements contained in this Amendment shall in any manner release, impair, lessen, modify,
waive, or otherwise affect the liability and obligations of Company under the terms of the Royalty Interest.
(d) Company
has no defenses, affirmative or otherwise, rights of setoff, rights of recoupment, claims, counterclaims, actions or causes of action
of any kind or nature whatsoever against Investor, directly or indirectly, arising out of, based upon, or in any manner connected with,
the transactions contemplated hereby, whether known or unknown, which occurred, existed, was taken, permitted, or begun prior to the execution
of this Amendment and occurred, existed, was taken, permitted or begun in accordance with, pursuant to, or by virtue of any of the terms
or conditions of the Royalty Interest. To the extent any such defenses, affirmative or otherwise, rights of setoff, rights of recoupment,
claims, counterclaims, actions or causes of action exist or existed, such defenses, rights, claims, counterclaims, actions and causes
of action are hereby waived, discharged and released. Company hereby acknowledges and agrees that the execution of this Amendment by Investor
shall not constitute an acknowledgment of or admission by Investor of the existence of any claims or of liability for any matter or precedent
upon which any claim or liability may be asserted.
(e) Company
represents and warrants that as of the date hereof no Events of Default or other material breaches exist under the Royalty Interest, or
have occurred prior to the date hereof.
5. Other
Terms Unchanged. The Royalty Interest, as amended by this Amendment, remains and continues in full force and effect, constitutes legal,
valid, and binding obligations of each of the parties, and is in all respects agreed to, ratified, and confirmed. Any reference to the
Royalty Interest after the date of this Amendment is deemed to be a reference to the Royalty Interest as amended by this Amendment. If
there is a conflict between the terms of this Amendment and the Royalty Interest, the terms of this Amendment shall control. No forbearance
or waiver may be implied by this Amendment. Company acknowledges that it is unconditionally obligated to pay the remaining balance of
the Royalty Interest and represents that such obligation is not subject to any deductions, defenses, rights of offset, or counterclaims
of any kind. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver
of, or as an amendment to, any right, power, or remedy of Investor under the Royalty Interest, as in effect prior to the date hereof.
6. No
Reliance. Company acknowledges and agrees that neither Investor nor any of its officers, directors, members, managers, equity holders,
representatives or agents has made any representations or warranties to Company or any of its agents, representatives, officers, directors,
or employees except as expressly set forth in this Amendment and the Royalty Interest and, in making its decision to enter into the transactions
contemplated by this Amendment, Company is not relying on any representation, warranty, covenant or promise of Investor or its officers,
directors, members, managers, equity holders, agents or representatives other than as set forth in this Amendment.
7. Counterparts.
This Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall
constitute one instrument. The parties hereto confirm that any electronic copy of another party’s executed counterpart of this Amendment
(or such party’s signature page thereof) will be deemed to be an executed original thereof.
8. Further
Assurances. Each party shall do and perform or cause to be done and performed, all such further acts and things, and shall execute
and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to
carry out the intent and accomplish the purposes of this Amendment and the consummation of the transactions contemplated hereby.
[Remainder of page intentionally left blank]
IN WITNESS WHEREOF, the undersigned have executed
this Amendment as of the date set forth above.
|
COMPANY: |
|
|
|
JAGUAR
HEALTH, Inc. |
|
|
|
By: |
/s/ Lisa Conte |
|
|
Lisa Conte, President and CEO |
|
INVESTOR: |
|
|
|
STREETERVILLE CAPITAL, LLC |
|
|
|
By: |
/s/ John M. Fife |
|
|
John M. Fife, President |
EXHIBITS:
Exhibit A Warrant
[Signature Page to Global
Amendment #2]
Exhibit 4.5
NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH
THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE
IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND,
ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT
TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE
WITH APPLICABLE STATE SECURITIES LAWS, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY. THIS SECURITY AND THE SECURITIES
ISSUABLE UPON EXERCISE OF THIS SECURITY MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN SECURED BY SUCH
SECURITIES.
COMMON STOCK PURCHASE WARRANT
JAGUAR HEALTH, INC.
Warrant No.:
Warrant Shares:
Date of Issuance: [______], 2023 (the “Issuance Date”)
THIS COMMON STOCK PURCHASE
WARRANT (the “Warrant”) certifies that, for value received, [________] or its assigns (the “Holder”)
is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time during the
period (the “Exercise Period”) commencing on the Issuance Date (the “Initial Exercise Date”) and
ending on or prior to the close of business on the five (5) year anniversary of the Initial Exercise Date (the “Termination
Date”) but not thereafter, to subscribe for and purchase from Jaguar Health, Inc., a Delaware corporation (the “Company”),
up to [______] ([______]) shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The
purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).
Section 1. Definitions.
Capitalized terms used and not otherwise defined herein shall have the meanings set forth in that certain Royalty Interest, dated [______],
between the Company and Holder (as amended, the “Agreement”).
Section 2. Exercise.
(a) Exercise
of Warrant. Exercise of the purchase rights represented by this Warrant may be made, in whole or in part, at any time or times on
or after the Initial Exercise Date and on or before the Termination Date by delivery to the Company (or such other office or agency that
the Company may designate by notice in writing to the registered Holder at the address of the Holder appearing on the books of the Company)
of a duly executed facsimile copy or PDF copy submitted by electronic (or e-mail attachment) of the Notice of Exercise in the form annexed
hereto (the “Notice of Exercise”). Within the earlier of (i) two (2) Trading Days and (ii) the number
of Trading Days comprising the Standard Settlement Period (as defined in Section 2(d)(i) herein) following the date of exercise
as aforesaid, the Holder shall deliver the aggregate Exercise Price for the shares specified in the applicable Notice of Exercise by wire
transfer or cashier’s check drawn on a United States bank unless the cashless exercise procedure specified in Section 2(c) below
is specified in the applicable Notice of Exercise. No ink-original Notice of Exercise shall be required, nor shall any medallion guarantee
(or other type of guarantee or notarization) of any Notice of Exercise form be required. Notwithstanding anything herein to the contrary,
the Holder shall not be required to physically surrender this Warrant to the Company until the Holder has purchased all of the Warrant
Shares available hereunder and the Warrant has been exercised in full, in which case, the Holder shall surrender this Warrant to the Company
for cancellation within three (3) Trading Days of the date the final Notice of Exercise is delivered to the Company. Partial exercises
of this Warrant resulting in purchases of a portion of the total number of Warrant Shares available hereunder shall have the effect of
lowering the outstanding number of Warrant Shares purchasable hereunder in an amount equal to the applicable number of Warrant Shares
purchased. The Holder and the Company shall maintain records showing the number of Warrant Shares purchased and the date of such purchases.
The Company shall deliver any objection to any Notice of Exercise within one (1) Business Day of receipt of such notice. The Holder
and any assignee, by acceptance of this Warrant, acknowledge and agree that, by reason of the provisions of this paragraph, following
the purchase of a portion of the Warrant Shares hereunder, the number of Warrant Shares available for purchase hereunder at any given
time may be less than the amount stated on the face hereof. In no event will the Company be required to net cash settle a Warrant exercise.
(b) Exercise
Price. The exercise price per share of the Common Stock under this Warrant shall be $0.37, subject to adjustment hereunder (the “Exercise
Price”).
(c) Cashless
Exercise. Notwithstanding anything to the contrary herein, this Warrant may also be exercised, in whole or in part, by means of a
“cashless exercise” in which the Holder shall be entitled to receive a number of Warrant Shares equal to the quotient obtained
by dividing [(A-B) (X)] by (A), where:
| (A) = | as applicable: (i) the VWAP on the Trading Day immediately
preceding the date of the applicable Notice of Exercise if such Notice of Exercise is (1) both executed and delivered pursuant to
Section 2(a) hereof on a day that is not a Trading Day or (2) both executed and delivered pursuant to Section 2(a) hereof
on a Trading Day prior to the opening of “regular trading hours” (as defined in Rule 600(b)(64) of Regulation NMS promulgated
under the federal securities laws) on such Trading Day, (ii) at the option of the Holder, either (y) the VWAP on the Trading
Day immediately preceding the date of the applicable Notice of Exercise or (z) the Bid Price of the Common Stock on the principal
Trading Market as reported by Bloomberg L.P. as of the time of the Holder’s execution of the applicable Notice of Exercise if such
Notice of Exercise is executed during “regular trading hours” on a Trading Day and is delivered within two (2) hours
thereafter (including until two (2) hours after the close of “regular trading hours” on a Trading Day) pursuant to Section 2(a) hereof
or (iii) the VWAP on the date of the applicable Notice of Exercise if the date of such Notice of Exercise is a Trading Day and such
Notice of Exercise is both executed and delivered pursuant to Section 2(a) hereof after the close of “regular trading
hours” on such Trading Day; |
| (B) = | the Exercise Price of this Warrant, as adjusted hereunder;
and |
| (X) = | the number of Warrant Shares that would be issuable upon exercise
of this Warrant in accordance with the terms of this Warrant if such exercise were by means of a cash exercise rather than a cashless
exercise. |
“VWAP” means,
for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed or
quoted on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding date)
on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg L.P. (based on a Trading Day from 9:30
a.m. (New York City time) to 4:02 p.m. (New York City time)), (b) if OTCQB or OTCQX is not a Trading Market, the volume
weighted average price of the Common Stock for such date (or the nearest preceding date) on OTCQB or OTCQX as applicable, (c) if
the Common Stock is not then listed or quoted for trading on OTCQB or OTCQX and if prices for the Common Stock are then reported in the
“Pink Sheets” published by OTC Markets Group, Inc. (or a similar organization or agency succeeding to its functions of
reporting prices), the most recent bid price per share of the Common Stock so reported, or (d) in all other cases, the fair market
value of a share of Common Stock as determined by in good faith by the Company.
Notwithstanding anything herein
to the contrary, upon (i) the closing of (x) a merger, reorganization, tender offer or similar transaction involving the Company
or its securities with or into another entity in which the holders of voting securities of the Company immediately prior to such transaction
will hold less than 50% of the voting securities of the surviving entity immediately following such transaction as a result of shares
held prior to such transaction or (y) a sale or license of all or substantially all of the assets of the Company (each, a “Fundamental
Transaction”), or (ii) the effectuation of any liquidation, dissolution or winding-up of the Corporation, whether voluntary
or involuntary (each, a “Liquidation Event”), this Warrant shall be automatically exercised via cashless exercise pursuant
to this Section 2(c).
Notwithstanding anything herein
to the contrary, on the Termination Date, this Warrant shall be automatically exercised via cashless exercise pursuant to this Section 2(c).
If Warrant Shares are issued
in a cashless exercise pursuant to this Section 2(c), the parties acknowledge and agree that in accordance with Section 3(a)(9) of
the Securities Act, the Warrant Shares shall take on the registered characteristics of the Warrants being exercised. The Company agrees
not to take any position contrary to this Section 2(c).
(d) Mechanics
of Exercise.
(i) Delivery
of Warrant Shares Upon Exercise. The Company shall cause the Warrant Shares purchased hereunder to be transmitted by the Transfer
Agent to the Holder by crediting the account of the Holder’s or its designee’s balance account with The Depository Trust Company
through its Deposit or Withdrawal at Custodian system (“DWAC”) if the Company is then a participant in such system
and either (A) there is an effective registration statement permitting the issuance of the Warrant Shares to or resale of the Warrant
Shares by Holder or (B) this Warrant is being exercised via cashless exercise, and otherwise by physical delivery of a certificate,
registered in the Company’s share register in the name of the Holder or its designee, for the number of Warrant Shares to which
the Holder is entitled pursuant to such exercise to the address specified by the Holder in the Notice of Exercise by the date that is
the earliest of (i) two (2) Trading Days after the delivery to the Company of the Notice of Exercise, (ii) one (1) Trading
Day after delivery of the aggregate Exercise Price to the Company and (iii) the number of Trading Days comprising the Standard Settlement
Period after the delivery to the Company of the Notice of Exercise (such date, the “Warrant Share Delivery Date”).
Upon delivery of the Notice of Exercise, the Holder shall be deemed for all corporate purposes to have become the holder of record of
the Warrant Shares with respect to which this Warrant has been exercised, irrespective of the date of delivery of the Warrant Shares,
provided that payment of the aggregate Exercise Price (other than in the case of a cashless exercise) is received within the earlier of
(i) two (2) Trading Days and (ii) the number of Trading Days comprising the Standard Settlement Period following delivery
of the Notice of Exercise. The Company agrees to maintain a transfer agent that is a participant in the FAST program so long as this Warrant
remains outstanding and exercisable. As used herein, “Standard Settlement Period” means the standard settlement period, expressed
in a number of Trading Days, on the Company’s primary Trading Market with respect to the Common Stock as in effect on the date of
delivery of the Notice of Exercise.
(ii) Delivery
of New Warrants Upon Exercise. If this Warrant shall have been exercised in part, the Company shall, at the request of a Holder and
upon surrender of this Warrant certificate, at the time of delivery of the Warrant Shares, deliver to the Holder a new Warrant evidencing
the rights of the Holder to purchase the unpurchased Warrant Shares called for by this Warrant, which new Warrant shall in all other respects
be identical with this Warrant.
(iii) Rescission
Rights. If the Company fails to cause the Transfer Agent to transmit to the Holder the Warrant Shares pursuant to Section 2(d)(i) by
the Warrant Share Delivery Date, then the Holder will have the right to rescind such exercise.
(iv) No
Fractional Shares or Scrip. No fractional shares or scrip representing fractional shares shall be issued upon the exercise of this
Warrant. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the Company shall,
at its election, either pay a cash adjustment in respect of such final fraction in an amount equal to such fraction multiplied by the
Exercise Price or round up to the next whole share.
(v) Charges,
Taxes and Expenses. Issuance of Warrant Shares shall be made without charge to the Holder for any issue or transfer tax or other incidental
expense in respect of the issuance of such Warrant Shares, all of which taxes and expenses shall be paid by the Company, and such Warrant
Shares shall be issued in the name of the Holder or in such name or names as may be directed by the Holder; provided, however,
that in the event that Warrant Shares are to be issued in a name other than the name of the Holder, this Warrant when surrendered for
exercise shall be accompanied by the Assignment Form attached hereto duly executed by the Holder and the Company may require, as
a condition thereto, the payment of a sum sufficient to reimburse it for any transfer tax incidental thereto. The Company shall pay all
Transfer Agent fees required for same-day processing of any Notice of Exercise and all fees to the Depository Trust Company (or another
established clearing corporation performing similar functions) required for same-day electronic delivery of the Warrant Shares.
(vi) Closing
of Books. The Company will not close its stockholder books or records in any manner which prevents the timely exercise of this Warrant,
pursuant to the terms hereof.
(e) Holder’s
Exercise Limitations. The Company shall not effect any exercise of this Warrant, and a Holder shall not have the right to exercise
any portion of this Warrant, pursuant to Section 2 or otherwise, to the extent that after giving effect to such issuance after exercise
as set forth on the applicable Notice of Exercise, the Holder (together with the Holder’s Affiliates, and any other Persons acting
as a group together with the Holder or any of the Holder’s Affiliates (such Persons, “Attribution Parties”)),
would beneficially own in excess of the Beneficial Ownership Limitation (as defined below). For purposes of the foregoing sentence, the
number of shares of Common Stock beneficially owned by the Holder and its Affiliates and Attribution Parties shall include the number
of shares of Common Stock issuable upon exercise of this Warrant with respect to which such determination is being made, but shall exclude
the number of shares of Common Stock which would be issuable upon (i) exercise of the remaining, nonexercised portion of this Warrant
beneficially owned by the Holder or any of its Affiliates or Attribution Parties and (ii) exercise or conversion of the unexercised
or nonconverted portion of any other securities of the Company (including, without limitation, any other Common Stock Equivalents) subject
to a limitation on conversion or exercise analogous to the limitation contained herein beneficially owned by the Holder or any of its
Affiliates or Attribution Parties. Except as set forth in the preceding sentence, for purposes of this Section 2(e), beneficial ownership
shall be calculated in accordance with Section 13(d) of the Exchange Act and the rules and regulations promulgated thereunder,
it being acknowledged by the Holder that the Company is not representing to the Holder that such calculation is in compliance with Section 13(d) of
the Exchange Act and the Holder is solely responsible for any schedules required to be filed in accordance therewith. To the extent that
the limitation contained in this Section 2(e) applies, the determination of whether this Warrant is exercisable (in relation
to other securities owned by the Holder together with any Affiliates and Attribution Parties) and of which portion of this Warrant is
exercisable shall be in the sole discretion of the Holder, and the submission of a Notice of Exercise shall be deemed to be the Holder’s
determination of whether this Warrant is exercisable (in relation to other securities owned by the Holder together with any Affiliates
and Attribution Parties) and of which portion of this Warrant is exercisable, in each case subject to the Beneficial Ownership Limitation,
and the Company shall have no obligation to verify or confirm the accuracy of such determination. In addition, a determination as to any
group status as contemplated above shall be determined in accordance with Section 13(d) of the Exchange Act and the rules and
regulations promulgated thereunder. For purposes of this Section 2(e), in determining the number of outstanding shares of Common
Stock, a Holder may rely on the number of outstanding shares of Common Stock as reflected in (A) the Company’s most recent
periodic or annual report filed with the Commission, as the case may be, (B) a more recent public announcement by the Company or
(C) a more recent written notice by the Company or the Transfer Agent setting forth the number of shares of Common Stock outstanding.
Upon the written or oral request of a Holder, the Company shall within two Trading Days confirm orally and in writing to the Holder the
number of shares of Common Stock then outstanding. In any case, the number of outstanding shares of Common Stock shall be determined after
giving effect to the conversion or exercise of securities of the Company, including this Warrant, by the Holder or its Affiliates or Attribution
Parties since the date as of which such number of outstanding shares of Common Stock was reported. The “Beneficial Ownership
Limitation” shall be 4.99% of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance
of shares of Common Stock issuable upon exercise of this Warrant. The Holder, upon notice to the Company, may increase or decrease the
Beneficial Ownership Limitation provisions of this Section 2(e), provided that the Beneficial Ownership Limitation in no event exceeds
9.99% of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock
upon exercise of this Warrant held by the Holder and the provisions of this Section 2(e) shall continue to apply. Any increase
in the Beneficial Ownership Limitation will not be effective until the 61st day after such notice is delivered to the Company. The provisions
of this paragraph shall be construed and implemented in a manner otherwise than in strict conformity with the terms of this Section 2(e) to
correct this paragraph (or any portion hereof) which may be defective or inconsistent with the intended Beneficial Ownership Limitation
herein contained or to make changes or supplements necessary or desirable to properly give effect to such limitation. The limitations
contained in this paragraph shall apply to a successor holder of this Warrant.
Section 3. Certain
Adjustments.
(a) Stock
Dividends and Splits. If the Company, at any time while this Warrant is outstanding: (i) pays a stock dividend or otherwise makes
a distribution or distributions on shares of its Common Stock or any other equity or equity equivalent securities payable in shares of
Common Stock (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Company upon exercise of this
Warrant), (ii) subdivides outstanding shares of Common Stock into a larger number of shares, (iii) combines (including by way
of reverse stock split) outstanding shares of Common Stock into a smaller number of shares or (iv) issues by reclassification of
shares of the Common Stock any shares of capital stock of the Company, then in each case the Exercise Price shall be multiplied by a fraction
of which the numerator shall be the number of shares of Common Stock (excluding treasury shares, if any) outstanding immediately before
such event and of which the denominator shall be the number of shares of Common Stock outstanding immediately after such event, and the
number of shares issuable upon exercise of this Warrant shall be proportionately adjusted such that the aggregate Exercise Price of this
Warrant shall remain unchanged. Any adjustment made pursuant to this Section 3(a) shall become effective immediately after the
record date for the determination of stockholders entitled to receive such dividend or distribution and shall become effective immediately
after the effective date in the case of a subdivision, combination or re-classification.
(b) Subsequent
Rights Offerings. In addition to any adjustments pursuant to Section 3(a) above, if at any time the Company grants, issues
or sells any Common Stock Equivalents or rights to purchase stock, warrants, securities or other property pro rata to the record holders
of any class of shares of Common Stock (the “Purchase Rights”), then the Holder will be entitled to acquire, upon the
terms applicable to such Purchase Rights, the aggregate Purchase Rights which the Holder could have acquired if the Holder had held the
number of shares of Common Stock acquirable upon complete exercise of this Warrant (without regard to any limitations on exercise hereof,
including without limitation, the Beneficial Ownership Limitation) immediately before the date on which a record is taken for the grant,
issuance or sale of such Purchase Rights, or, if no such record is taken, the date as of which the record holders of shares of Common
Stock are to be determined for the grant, issue or sale of such Purchase Rights (provided, however, to the extent that the Holder’s
right to participate in any such Purchase Right would result in the Holder exceeding the Beneficial Ownership Limitation, then the Holder
shall not be entitled to participate in such Purchase Right to such extent (or beneficial ownership of such shares of Common Stock as
a result of such Purchase Right to such extent) and such Purchase Right to such extent shall be held in abeyance for the Holder until
such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership Limitation).
(c) Pro
Rata Distributions. During such time as this Warrant is outstanding, if the Company shall declare or make any dividend or other distribution
of its assets (or rights to acquire its assets) to holders of shares of Common Stock, by way of return of capital or otherwise (including,
without limitation, any distribution of cash, stock or other securities, property or options by way of a dividend, spin off, reclassification,
corporate rearrangement, scheme of arrangement or other similar transaction) (a “Distribution”), at any time after
the issuance of this Warrant, then, in each such case, the Holder shall be entitled to participate in such Distribution to the same extent
that the Holder would have participated therein if the Holder had held the number of shares of Common Stock acquirable upon complete exercise
of this Warrant (without regard to any limitations on exercise hereof, including without limitation, the Beneficial Ownership Limitation)
immediately before the date of which a record is taken for such Distribution, or, if no such record is taken, the date as of which the
record holders of shares of Common Stock are to be determined for the participation in such Distribution (provided, however,
to the extent that the Holder’s right to participate in any such Distribution would result in the Holder exceeding the Beneficial
Ownership Limitation, then the Holder shall not be entitled to participate in such Distribution to such extent (or in the beneficial ownership
of any shares of Common Stock as a result of such Distribution to such extent) and the portion of such Distribution shall be held in abeyance
for the benefit of the Holder until such time, if ever, as its right thereto would not result in the Holder exceeding the Beneficial Ownership
Limitation). To the extent that this Warrant has not been partially or completely exercised at the time of such Distribution, such portion
of the Distribution shall be held in abeyance for the benefit of the Holder until the Holder has exercised this Warrant.
(d) Calculations.
All calculations under this Section 3 shall be made to the nearest cent or the nearest 1/100th of a share, as the case may be. For
purposes of this Section 3, the number of shares of Common Stock deemed to be issued and outstanding as of a given date shall be
the sum of the number of shares of Common Stock (excluding treasury shares, if any) issued and outstanding.
(e) Notice
to Holder.
(i) Adjustment
to Exercise Price. Whenever the Exercise Price is adjusted pursuant to any provision of this Section 3, the Company shall promptly
deliver to the Holder by facsimile or email a notice setting forth the Exercise Price after such adjustment and any resulting adjustment
to the number of Warrant Shares and setting forth a brief statement of the facts requiring such adjustment.
(ii) Notice
to Allow Exercise by Holder. If (A) the Company shall declare a dividend (or any other distribution in whatever form) on the
Common Stock, (B) the Company shall declare a special nonrecurring cash dividend on or a redemption of the Common Stock, (C) the
Company shall authorize the granting to all holders of the Common Stock rights or warrants to subscribe for or purchase any shares of
capital stock of any class or of any rights, (D) the Company effects a Fundamental Transaction, or (E) a Liquidation Event,
then, in each case, the Company shall cause to be delivered by facsimile or email to the Holder at its last facsimile number or email
address as it shall appear upon the Warrant Register of the Company, at least ten (10) calendar days prior to the applicable record
or effective date hereinafter specified, a notice stating (x) the date on which a record is to be taken for the purpose of such dividend,
distribution, redemption, rights or warrants, or if a record is not to be taken, the date as of which the holders of the Common Stock
of record to be entitled to such dividend, distributions, redemption, rights or warrants are to be determined or (y) the date on
which such Fundamental Transaction is expected to become effective or close, and the date as of which it is expected that holders of the
Common Stock of record shall be entitled to exchange their shares of the Common Stock for securities, cash or other property deliverable
upon such Fundamental Transaction; provided that the failure to deliver such notice or any defect therein or in the delivery thereof shall
not affect the validity of the corporate action required to be specified in such notice. To the extent that any notice provided in this
Warrant constitutes, or contains, material, non-public information regarding the Company or any of the Subsidiaries, the Company shall
simultaneously file such notice with the Commission pursuant to a Current Report on Form 8-K. The Holder shall remain entitled to
exercise this Warrant during the period commencing on the date of such notice to the effective date of the event triggering such notice
except as may otherwise be expressly set forth herein.
Section 4. Transfer
of Warrant.
(a) Transferability.
Subject to compliance with any applicable securities laws and the conditions set forth in Section 4(d) hereof, this Warrant
and all rights hereunder (including, without limitation, any registration rights) are transferable, in whole or in part, upon surrender
of this Warrant at the principal office of the Company or its designated agent, together with a written assignment of this Warrant substantially
in the form attached hereto duly executed by the Holder or its agent or attorney and funds sufficient to pay any transfer taxes payable
upon the making of such transfer. Upon such surrender and, if required, such payment, the Company shall execute and deliver a new Warrant
or Warrants in the name of the assignee or assignees, as applicable, and in the denomination or denominations specified in such instrument
of assignment, and shall issue to the assignor a new Warrant evidencing the portion of this Warrant not so assigned, and this Warrant
shall promptly be cancelled. Notwithstanding anything herein to the contrary, the Holder shall not be required to physically surrender
this Warrant to the Company unless the Holder has assigned this Warrant in full, in which case, the Holder shall surrender this Warrant
to the Company within three (3) Trading Days of the date on which the Holder delivers an assignment form to the Company assigning
this Warrant in full. The Warrant, if properly assigned in accordance herewith, may be exercised by a new holder for the purchase of Warrant
Shares without having a new Warrant issued.
(b) New
Warrants. This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of the Company,
together with a written notice specifying the names and denominations in which new Warrants are to be issued, signed by the Holder or
its agent or attorney. Subject to compliance with Section 4(a), as to any transfer which may be involved in such division or combination,
the Company shall execute and deliver a new Warrant or Warrants in exchange for the Warrant or Warrants to be divided or combined in accordance
with such notice. All Warrants issued on transfers or exchanges shall be dated the Issuance Date and shall be identical with this Warrant
except as to the number of Warrant Shares issuable pursuant thereto.
(c) Warrant
Register. The Company shall register this Warrant, upon records to be maintained by the Company for that purpose (the “Warrant
Register”), in the name of the record Holder hereof from time to time. The Company may deem and treat the registered Holder
of this Warrant as the absolute owner hereof for the purpose of any exercise hereof or any distribution to the Holder, and for all other
purposes, absent actual notice to the contrary.
(d) Representation
by the Holder. The Holder, by the acceptance hereof, represents and warrants that it is acquiring this Warrant and, upon any exercise
hereof, will acquire the Warrant Shares issuable upon such exercise, for its own account and not with a view to or for distributing or
reselling such Warrant Shares or any part thereof in violation of the Securities Act or any applicable state securities law, except pursuant
to sales registered or exempted under the Securities Act.
Section 5. Miscellaneous.
(a) No
Rights as Stockholder Until Exercise. This Warrant does not entitle the Holder to any voting rights, dividends or other rights as
a stockholder of the Company prior to the exercise hereof as set forth in Section 2(d)(i), except as expressly set forth in Section 3.
(b) Loss,
Theft, Destruction or Mutilation of Warrant. The Company covenants that upon receipt by the Company of evidence reasonably satisfactory
to it of the loss, theft, destruction or mutilation of this Warrant or any stock certificate relating to the Warrant Shares, and in case
of loss, theft or destruction, of indemnity or security reasonably satisfactory to it (which, in the case of the Warrant, shall not include
the posting of any bond), and upon surrender and cancellation of such Warrant or stock certificate, if mutilated, the Company will make
and deliver a new Warrant or stock certificate of like tenor and dated as of such cancellation, in lieu of such Warrant or stock certificate.
(c) Saturdays,
Sundays, Holidays, etc. If the last or appointed day for the taking of any action or the expiration of any right required or
granted herein shall not be a Business Day, then, such action may be taken or such right may be exercised on the next succeeding Business
Day.
(d) Authorized
Shares.
The Company covenants that,
during the period this Warrant is outstanding, it will reserve from its authorized and unissued Common Stock a sufficient number of shares
to provide for the issuance of the Warrant Shares upon the exercise of any purchase rights under this Warrant. The Company further covenants
that its issuance of this Warrant shall constitute full authority to its officers who are charged with the duty of issuing the necessary
Warrant Shares upon the exercise of the purchase rights under this Warrant. The Company will take all such reasonable action as may be
necessary to assure that such Warrant Shares may be issued as provided herein without violation of any applicable law or regulation, or
of any requirements of the Trading Market upon which the Common Stock may be listed. The Company covenants that all Warrant Shares which
may be issued upon the exercise of the purchase rights represented by this Warrant will, upon exercise of the purchase rights represented
by this Warrant and payment for such Warrant Shares in accordance herewith, be duly authorized, validly issued, fully paid and nonassessable
and free from all taxes, liens and charges created by the Company in respect of the issue thereof (other than taxes in respect of any
transfer occurring contemporaneously with such issue).
Except and to the extent as
waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending its certificate of
incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or sale of securities or any
other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will at all times
in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate to
protect the rights of Holder as set forth in this Warrant against impairment. Without limiting the generality of the foregoing, the Company
will (i) not increase the par value of any Warrant Shares above the amount payable therefor upon such exercise immediately prior
to such increase in par value, (ii) take all such action as may be necessary or appropriate in order that the Company may validly
and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant and (iii) use commercially reasonable
efforts to obtain all such authorizations, exemptions or consents from any public regulatory body having jurisdiction thereof, as may
be, necessary to enable the Company to perform its obligations under this Warrant.
Before taking any action which
would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the Exercise Price, the Company
shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary from any public regulatory body or
bodies having jurisdiction thereof.
(e) Jurisdiction.
All questions concerning the construction, validity, enforcement and interpretation of this Warrant shall be determined in accordance
with the provisions of the Purchase Agreement.
(f) Restrictions.
The Holder acknowledges that the Warrant Shares acquired upon the exercise of this Warrant, if not registered and the Holder does not
utilize cashless exercise, will have restrictions upon resale imposed by state and federal securities laws.
(g) Nonwaiver
and Expenses. No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall operate as
a waiver of such right or otherwise prejudice the Holder’s rights, powers or remedies, notwithstanding the fact that all rights
hereunder terminate on the Termination Date. If the Company willfully and knowingly fails to comply with any provision of this Warrant,
which results in any material damages to the Holder, the Company shall pay to the Holder such amounts as shall be sufficient to cover
any costs and expenses including, but not limited to, reasonable attorneys’ fees, including those of appellate proceedings, incurred
by the Holder in collecting any amounts due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.
(h) Notices.
Any notice, request or other document required or permitted to be given or delivered to the Holder by the Company shall be delivered in
accordance with the notice provisions of the Purchase Agreement.
(i) Limitation
of Liability. No provision hereof, in the absence of any affirmative action by the Holder to exercise this Warrant to purchase Warrant
Shares, and no enumeration herein of the rights or privileges of the Holder, shall give rise to any liability of the Holder for the purchase
price of any Common Stock or as a stockholder of the Company, whether such liability is asserted by the Company or by creditors of the
Company.
(j) Remedies.
The Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will be entitled to specific
performance of its rights under this Warrant. The Company agrees that monetary damages would not be adequate compensation for any loss
incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive and not to assert the defense in any
action for specific performance that a remedy at law would be adequate.
(k) Successors
and Assigns. Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall inure to the
benefit of and be binding upon the successors and permitted assigns of the Company and the successors and permitted assigns of Holder.
The provisions of this Warrant are intended to be for the benefit of any Holder from time to time of this Warrant and shall be enforceable
by the Holder or holder of Warrant Shares.
(l) Amendment.
This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company and the Holder.
(m) Severability.
Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid under applicable law,
but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall be ineffective to the
extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining provisions of this Warrant.
(n) Headings.
The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed a part of this Warrant.
********************
(Signature Page Follows)
IN
WITNESS WHEREOF, the Company has caused this Warrant to be executed by its officer thereunto duly authorized as of the date
first above indicated.
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JAGUAR HEALTH, INC. |
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Name: Lisa A. Conte |
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Title: CEO and President |
Signature
Page to Warrant
EXHIBIT A
NOTICE OF EXERCISE
TO: JAGUAR HEALTH, INC.
(1) The
undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant, and tenders
herewith payment of the exercise price in full, together with all applicable transfer taxes, if any.
(2) Payment
shall take the form of (check applicable box):
¨ in lawful
money of the United States; or
¨
the cancellation of such number of Warrant Shares as is necessary, in accordance with the formula set forth in subsection 2(c),
to exercise this Warrant with respect to ________ Warrant Shares purchasable pursuant to the cashless exercise procedure set forth in
subsection 2(c).
(3) Please
issue said Warrant Shares in the name of the undersigned or in such other name as is specified below:
The Warrant Shares shall be delivered to the following DWAC Account
Number:
(4) Accredited
Investor. The undersigned is an “accredited investor” as defined in Regulation D promulgated under the Securities Act
of 1933, as amended.
[SIGNATURE OF HOLDER]
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Exhibit A
to Warrant
EXHIBIT B
ASSIGNMENT FORM
(To assign the foregoing Warrant, execute this
form and supply required information. Do not use this form to purchase shares.)
FOR VALUE RECEIVED, the foregoing Warrant and all
rights evidenced thereby are hereby assigned to
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Exhibit B
to Warrant
Exhibit 10.1
THE EXCHANGE CONTEMPLATED HEREIN IS INTENDED
TO COMPORT WITH THE REQUIREMENTS OF SECTION 3(a)(9) OF THE SECURITIES ACT OF 1933, AS AMENDED.
EXCHANGE AGREEMENT
This Exchange Agreement (this
“Agreement”) is entered into as of September 29, 2023 (the “Effective Date”) by and between
Uptown Capital, LLC, a Utah limited partnership (f/k/a Irving Park Capital, LLC) (“Investor”), and Jaguar Health, Inc.,
a Delaware corporation (“Borrower”). Capitalized terms used in this Agreement without definition shall have the meanings
given to them in the Royalty Interest (as defined below).
A. Company
previously sold and issued to Investor that certain Royalty Interest, as amended, dated December 22, 2020 (the “Royalty
Interest”) pursuant to that certain Royalty Interest Purchase Agreement dated December 22, 2020 (the “Purchase
Agreement,” and together with the Royalty Interest and all other documents entered into in conjunction therewith, the “Transaction
Documents”).
B. Subject
to the terms of this Agreement, Borrower and Investor desire to partition a new Royalty Interest in the Royalty Repayment Amount of $1,500,000.00
(the “Partitioned Royalty”) from the Royalty Interest and then cause the outstanding balance of the Royalty Interest
to be reduced by an amount equal to the initial outstanding balance of the Partitioned Royalty.
C. Borrower
and Investor further desire to exchange (such exchange is referred to as the “Royalty Exchange”) the Partitioned Royalty
for 118 shares of the Company’s Series I Convertible Preferred Stock, par value $0.0001 (the “Preferred Stock”,
and such 118 shares of Preferred Stock, the “Exchange Shares”), according to the terms and conditions of this Agreement.
D. The
Royalty Exchange will consist of Investor surrendering the Partitioned Royalty in exchange for the Exchange Shares.
E. Other
than the surrender of the Partitioned Royalty, no consideration of any kind whatsoever shall be given by Investor to Borrower in connection
with this Agreement.
F. Investor
and Borrower now desire to exchange the Partitioned Royalty for the Exchange Shares on the terms and conditions set forth herein.
NOW, THEREFORE, for good and
valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties agree as follows:
1. Recitals
and Definitions. Each of the parties hereto acknowledges and agrees that the recitals set forth above in this Agreement are true and
accurate, are contractual in nature, and are hereby incorporated into and made a part of this Agreement.
2. Partition.
Effective as of the date hereof, Borrower and Investor agree that the Partitioned Royalty is hereby partitioned from the Royalty
Interest. Following such partition of the Royalty Interest, Borrower and Investor agree that the Royalty Interest shall
remain in full force and effect, provided that the outstanding balance of the Royalty Interest shall be reduced by an amount equal
to the initial outstanding balance of the Partitioned Royalty. For avoidance of doubt, the rights, duties, obligations, remedies of
Borrower and Investor, and other terms and conditions of the Royalty Interest shall remain unchanged upon the entering into of this
Agreement, except with respect to the reduction in the outstanding balance by the amount of the Partitioned Royalty.
3. Issuance
of Shares. Pursuant to the terms and conditions of this Agreement, the Exchange Shares shall be delivered to Investor on or before
September 29, 2023 and the Royalty Exchange shall occur with Investor surrendering the Partitioned Royalty to Borrower on the date
the Exchage Shares are issued to Investor (the “Issuance Date” ). On the Issuance Date, the Partitioned Royalty shall
be cancelled and all obligations of Borrower under the Partitioned Royalty shall be deemed fulfilled. All Exchange Shares shall be issued
in book entry form.
4. Closing.
The closing of the transaction contemplated hereby (the “Closing”) along with the delivery of the Exchange Shares to
Investor shall occur on the date that is mutually agreed to by Borrower and Investor by means of the exchange by express courier and email
of .pdf documents, but shall be deemed to have occurred at the offices of Hansen Black Anderson Ashcraft PLLC in Lehi, Utah.
5. Holding
Period, Tacking and Legal Opinion. Borrower represents, warrants and agrees that for the purposes of Rule 144 (“Rule 144”)
of the Securities Act of 1933, as amended (the “Securities Act”), the holding period of the Partitioned Royalty and
the Exchange Shares will include Investor’s holding period of the Royalty Interest from December 22, 2020. Borrower agrees
not to take a position contrary to this Section 5 in any document, statement, setting, or situation. The Exchange Shares are being
issued in substitution of and exchange for and not in satisfaction of the Partitioned Royalty. The Exchange Shares shall not constitute
a novation or satisfaction and accord of the Partitioned Royalty. Borrower acknowledges and understands that the representations and agreements
of Borrower in this Section 5 are a material inducement to Investor’s decision to consummate the transactions contemplated
herein.
6. Borrower’s
Representations, Warranties and Agreements. In order to induce Investor to enter into this Agreement, Borrower, for itself, and for
its affiliates, successors and assigns, hereby acknowledges, represents, warrants and agrees as follows: (a) Borrower has full power
and authority to enter into this Agreement and to incur and perform all obligations and covenants contained herein, all of which have
been duly authorized by all proper and necessary action, (b) no consent, approval, filing or registration with or notice to any
governmental authority is required as a condition to the validity of this Agreement or the performance of any of the obligations of Borrower
hereunder, (c) no Event of Default has occurred under the Royalty Interest and any Events of Default that may have occurred thereunder
have not been, and are not hereby, waived by Investor, (d) except as specifically set forth herein, nothing herein shall in any
manner release, lessen, modify or otherwise affect Borrower’s obligations under the Royalty Interest, (e) the issuance of
the Exchange Shares is duly authorized by all necessary corporate action and the Exchange Shares are validly issued, fully paid and non-assessable,
free and clear of all taxes, liens, claims, pledges, mortgages, restrictions, obligations, security interests and encumbrances of any
kind, nature and description, (f) Borrower has not received any consideration in any form whatsoever for entering into this Agreement,
other than the surrender of the Partitioned Royalty, and (g) Borrower has taken no action which would give rise to any claim by
any person for a brokerage commission, placement agent or finder’s fee or other similar payment by Borrower related to this Agreement.
7. Investor’s
Representations, Warranties and Agreements. In order to induce Borrower to enter into this Agreement, Investor, for itself,
and for its affiliates, successors and assigns, hereby acknowledges, represents, warrants and agrees as follows: (a) Investor
has full power and authority to enter into this Agreement and to incur and perform all obligations and covenants contained herein,
all of which have been duly authorized by all proper and necessary action, (b) no consent, approval, filing or registration
with or notice to any governmental authority is required as a condition to the validity of this Agreement or the performance of any
of the obligations of Investor hereunder, (c) Investor has taken no action which would give rise to any claim by any person for
a brokerage commission, placement agent or finder’s fee or other similar payment by Borrower related to this Agreement,
(d) Investor is not currently an affiliate of the Borrower and has not been an affiliate of the Borrower for the prior three
months, and (f) Investor, together with its affiliates, does not, and will not following the receipt of the Exchange Shares,
beneficially own more than 9.99% of the number of shares of Borrower’s common stock, par value $0.0001 (the “Common
Stock”) outstanding on the Effective Date. For purposes of Section 7(f), beneficial ownership of Common Stock will be
determined pursuant to Section 13(d) of the Securities Exchange Act of 1934, as amended.
8. Governing
Law; Venue. This Agreement shall be construed and enforced in accordance with, and all questions concerning the construction, validity,
interpretation and performance of this Agreement shall be governed by, the internal laws of the State of Utah, without giving effect to
any choice of law or conflict of law provision or rule (whether of the State of Utah or any other jurisdictions) that would cause
the application of the laws of any jurisdictions other than the State of Utah. The provisions set forth in the Purchase Agreement to determine
the proper venue for any disputes are incorporated herein by this reference. The parties agree that the Arbitration Provisions shall apply
to any dispute that may arise between Borrower and Investor under this Agreement. BORROWER HEREBY IRREVOCABLY WAIVES ANY RIGHT
IT MAY HAVE TO, AND AGREES NOT TO REQUEST, A JURY TRIAL FOR THE ADJUDICATION OF ANY DISPUTE HEREUNDER OR IN CONNECTION WITH OR ARISING
OUT OF THIS AGREEMENT OR ANY TRANSACTION CONTEMPLATED HEREBY.
9. Counterparts.
This Agreement may be executed in any number of counterparts with the same effect as if all signing parties had signed the same document.
All counterparts shall be construed together and constitute the same instrument. The exchange of copies of this Agreement and of signature
pages by facsimile transmission or other electronic transmission (including email) shall constitute effective execution and delivery
of this Agreement as to the parties and may be used in lieu of the original Agreement for all purposes. Signatures of the parties transmitted
by facsimile transmission or other electronic transmission (including email) shall be deemed to be their original signatures for all purposes.
10. Attorneys’
Fees. In the event of any arbitration or action at law or in equity to enforce or interpret the terms of this Agreement, the parties
agree that the party who is awarded the most money shall be deemed the prevailing party for all purposes and shall therefore be entitled
to an additional award of the full amount of the attorneys’ fees and expenses paid by such prevailing party in connection with
the arbitration, litigation and/or dispute without reduction or apportionment based upon the individual claims or defenses giving rise
to the fees and expenses. Nothing herein shall restrict or impair an arbitrator’s or a court’s power to award fees and expenses
for frivolous or bad faith pleading.
11. No
Reliance. Borrower acknowledges and agrees that neither Investor nor any of its officers, directors, members, managers, equity holders,
representatives or agents has made any representations or warranties to Borrower or any of its agents, representatives, officers, directors,
or employees except as expressly set forth in this Agreement and the Transaction Documents and, in making its decision to enter into the
transactions contemplated by this Agreement, Borrower is not relying on any representation, warranty, covenant or promise of Investor
or its officers, directors, members, managers, equity holders, agents or representatives other than as set forth in this Agreement.
12. Severability.
If any part of this Agreement is construed to be in violation of any law, such part shall be modified to achieve the objective of the
parties to the fullest extent permitted and the balance of this Agreement shall remain in full force and effect.
13. Entire
Agreement. This Agreement, together with the Transaction Documents, and all other documents referred to herein, supersedes all other
prior oral or written agreements between Borrower, Investor, its affiliates and persons acting on its behalf with respect to the
matters discussed herein, and this Agreement and the instruments referenced herein contain the entire understanding of the parties with
respect to the matters covered herein and therein and, except as specifically set forth herein or therein, neither Investor nor Borrower
makes any representation, warranty, covenant or undertaking with respect to such matters.
14. Amendments.
This Agreement may be amended, modified, or supplemented only by written agreement of the parties. No provision of this Agreement may
be waived except in writing signed by the party against whom such waiver is sought to be enforced.
15. Successors
and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their respective successors and assigns.
This Agreement or any of the severable rights and obligations inuring to the benefit of or to be performed by Investor hereunder may be
assigned by Investor to a third party, including its financing sources, in whole or in part. Borrower may not assign this Agreement or
any of its obligations herein without the prior written consent of Investor.
16. Continuing
Enforceability; Conflict Between Documents. Except as otherwise modified by this Agreement, the Royalty Interest and each of the other
Transaction Documents shall remain in full force and effect, enforceable in accordance with all of its original terms and provisions.
This Agreement shall not be effective or binding unless and until it is fully executed and delivered by Investor and Borrower. If there
is any conflict between the terms of this Agreement, on the one hand, and the Royalty Interest or any other Transaction Document, on the
other hand, the terms of this Agreement shall prevail.
17. Time
of Essence. Time is of the essence with respect to each and every provision of this Agreement.
18. Notices.
Unless otherwise specifically provided for herein, all notices, demands or requests required or permitted under this Agreement to be
given to Borrower or Investor shall be given as set forth in the “Notices” section of the Purchase Agreement.
19. Further
Assurances. Each party shall do and perform or cause to be done and performed, all such further acts and things, and shall execute
and deliver all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to
carry out the intent and accomplish the purposes of this Agreement and the consummation of the transactions contemplated hereby.
[Remainder of page intentionally left blank]
IN WITNESS WHEREOF, the undersigned have executed
this Agreement as of the date first set forth above.
|
COMPANY: |
|
|
|
JAGUAR HEALTH, INC. |
|
|
|
By: |
/s/ Lisa A. Conte |
|
Name: |
Lisa A. Conte |
|
Title: |
President & CEO |
|
|
|
INVESTOR: |
|
|
|
UPTOWN CAPITAL, LLC |
|
|
|
By: |
/s/ John M. Fife |
|
|
John M. Fife, President |
[Signature Page to Exchange Agreement]
v3.23.3
Cover
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Sep. 29, 2023 |
Cover [Abstract] |
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8-K
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false
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Document Period End Date |
Sep. 29, 2023
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--12-31
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Entity File Number |
001-36714
|
Entity Registrant Name |
JAGUAR HEALTH, INC.
|
Entity Central Index Key |
0001585608
|
Entity Tax Identification Number |
46-2956775
|
Entity Incorporation, State or Country Code |
DE
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Entity Address, Address Line One |
200 Pine Street
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Entity Address, Address Line Two |
Suite 400
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Entity Address, City or Town |
San Francisco
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CA
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94104
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