Jugas
8 years ago
http://www.innovationintextiles.com/dryeing-finishing-printing/the-best-antimicrobial-technology-that-youve-never-heard-of/
7th March 2016, Hendersonville, NC
The Best Antimicrobial Technology That You’ve Never Heard Of
4 comments
Today’s antimicrobial treatments for textiles are usually marketed based on the concept of odour control, particularly for active and outdoor wear; and on the idea that textiles treated with antimicrobial agents can be washed less frequently.
But most consumers don’t really understand the chemistry of antimicrobial technologies; and those of us who are somewhat informed are vaguely uncomfortable with the idea of substances such as triclosan, quat-silane, and nano-silver applied to textiles that we wear against the skin.
Quick-Med Technologies has developed an antimicroial technology for textiles using hydrogen peroxide. © Quick-Med Technologies
What if there was an antimicrobial technology for textiles that is cost-effective yet highly durable; proven in medical wound care yet as consumer-friendly as laundry detergent; and that degrades into nothing more harmful than water and oxygen?
The wide-spread use of such a technology could go a long ways in reducing our global water crisis, according to Quick-Med Technologies, Inc., a publicly-traded life sciences company based in Florida that is focused on developing technologies for infection prevention and control for the healthcare and consumer markets.
Hydrogen peroxide, a natural antiseptic
According to David Lerner, founder of Quick-Med Technologies, that technology is currently available as a textile finish that is easily applied during the manufacturing process; or can even be applied to finished textiles as a post-treatment. It’s called Oxi Fresh™; and although it has no relationship to the laundry detergent OxiClean™, both are based on hydrogen peroxide (H202), recognized as a safe antimicrobial agent by the US Food and Drug Administration (FDA).
Consumers are familiar with hydrogen peroxide, Lerner pointed out, as a color-safe bleaching agent and stain fighter for laundering applications. Hydrogen peroxide functions by destroying the cell membrane as well as internal cell structures, thereby killing the microbe and inhibiting the growth of microbial colonies.
Hydrogen Peroxide is well-established as a safe and natural antimicrobial. © Quick-Med Technologies
Hydrogen peroxide has been proven to not only reduce the risk of infection dramatically, but to control microbe-driven odour and staining on textiles. Independent lab analysis using AATCC 100 showed that H202 delivered broad spectrum efficacy against a range of common pathogens and odour-causing bacteria.
Rebranding for consumer textiles
Oxi Fresh™ is, in essence, a consumer-facing rebranding of the company’s Stay-Fresh® technology: a hydrogen peroxide bleach that is permanently bound to textiles for consumer use. But whilst the concentration of H202 in antiseptics for medical use is about 3%, the amount used in Oxi Fresh™ is much less concentrated, according to Dr. Bernd Liesenfeld, Quick-Med Technologies’ president.
The inert binder is composed of zinc oxides and hydroxides, which are safely used on sensitive skin in barrier creams such as diaper cream and sunscreen products. Oxi Fresh™ has been validated to retain efficacy for up to 75 launderings at 105° F, with full kill on medical grade bacteria, virus, fungi and mould.
The Environmental Protection Agency (EPA) in the US has registered the Oxi Fresh™ technology for use in a wide range of consumer textile products.
“We feel the degree of testing we’ve done of H202 on wounds and compromised surfaces speaks to an appropriate level of safety,” said Liesenfeld, whose article describing the platform was published in the September/October 2013 edition of the AATCC Review.
Getting the word out to consumers
Quick-Med has licensed their antimicrobial technologies to various consumer and medical textile producers, such as Doris Hosiery, Polartec LLC, Sarasota Medical Products, and Medline. With the rebranding of Stay-Fresh® as Oxi Fresh™, Lerner is looking to take the product to the next level.
An 18-year veteran of the apparel trade, Lerner is focused on the benefits of Oxi Fresh™ to the consumer as well as to the supply chain side of the business. His primary message: textiles treated with Oxi Fresh™ need not be washed as frequently, and can be safely cleaned at lower temperatures, conserving water and energy, whilst conserving the integrity of the product for a longer wearable life.
“Quick-Med Technologies, Inc. has developed and commercialized Oxi Fresh™ as a new, game-changing, green, FDA/EPA-approved antimicrobial and preservative, a ‘No Wash’ product for the textile, apparel, and footwear industries,” Lerner enthused.
Oxi Fresh hopes to reduce the environmental impact of washing consumer textiles. © Quick-Med Technologies
“The average washing machine uses approximately 33 gallons of water per wash,” he continued. “This product will save millions of gallons of water normally used in home laundering and commercial applications.”
Whilst other antimicrobial technologies likewise tout the reduced need for laundering in marketing their products, Oxi Fresh™ would appear to have additional sustainable aspects.
“Oxi Fresh™ performs as well out-of-the-box as it does after 75 home launderings. It is not a heavy metal; it conserves water and energy; and has no detergent runoff into the environment,” Lerner pointed out.
Lerner also believes that Oxi Fresh™ offers potential benefits to the medical and hospitality businesses, where the cost of high-temperature laundering can be very high.
Supply chain positives
The Oxi Fresh™ licensing arrangement “adds pennies on the dollar” to the cost of finished textiles and garments, Lerner insisted. The technology is easily applied, requiring no special equipment, and presenting no discoloration issues.
The finished products stay fresher and cleaner, for longer, as the technology contains an inherent preservative that reduces inventory spoilage due to mould or humidity during transportation and storage.
“Water scarcity is an emerging problem, and getting worse,” Lerner reiterated. “This growing global challenge is creating opportunities for new and advanced textiles. While ‘green’ technologies are often considered more expensive or inconvenient, Oxi Fresh™ delivers real economic and product benefits to provide a win-win for suppliers, consumers, and the environment.”
- See more at: http://www.innovationintextiles.com/dryeing-finishing-printing/the-best-antimicrobial-technology-that-youve-never-heard-of/#sthash.w16auHKC.dpuf
Jugas
8 years ago
BIOGUARD® products employ Nimbus Technology and is licensed to: Derma Sciences, Inc.
In April, 2007, we entered into a license agreement with Derma Sciences Inc. for NIMBUS treatment of select substrates used in traditional wound care. In February, 2009 we received FDA market clearance for the NIMBUS gauze wound dressing licensed to Derma Sciences and in June, 2009 Derma Sciences reported first commercial sale of a product, BIOGUARD® wound dressings, employing our NIMBUS technology. Derma Sciences is marketing and selling the BIOGUARD product to the professional health care market including acute care hospitals, extended care hospitals, nursing homes, and wound care centers. In July 2012, we entered into a new license agreement with Derma Sciences that grants Derma a worldwide (except for India) exclusive license to our NIMBUS treatment of traditional wound dressings in return for $1.3 million in upfront payment, additional milestone payments and ongoing royalty payments.
Here are some of the BIOGUARD® products:
Websites carrying BIOGUARD® products:
http://www.hightidehealth.com/bioguard-barrier-dressings.html
http://www.medline.com/product/SPONGEBIOGUARD-ANTIMICROBIAL-12PL-4X4/Sponges/Z05-PF31309
http://www.dermasciences.com/bioguard-products
http://www.ebay.com/sch/sis.html?_nkw=Bioguard+Gauze+Bandages+97322+Lot+of+6+large+Rolls
http://www.woundsource.com/product/bioguard-barrier-dressings-conforming-bandages
http://www.vitalitymedical.com/bioguard-barrier-dressings.html
http://www.expressmed.com/product/wound-dressings/73959-63151/bioguard-gauze-roll.html
Jugas
8 years ago
Patents / Publication
Patents / Publication # Year of Publication / Issued Title
8,926,999 2015 Antimicrobial textiles comprising peroxide
8,545,862 2013 Polyelectrolyte complex for imparting antimicrobial properties to a substrate
2013/0011,491 2013 Antimicrobial Textiles Comprising Peroxide
8,277,827 2012 Antimicrobial textiles comprising peroxide
8,092,854 2012 Method of attaching an antimicrobial
cationic polyelectrolyte to the surface of a substrate
2011/0171,280 2011 Antimicrobial Textiles Comprising Peroxide
2010/0330,261 2010 METHOD OF ATTACHING AN ANTIMICROBIAL CATIONIC POLYELECTROLYTE TO THE SURFACE OF A SUBSTRATE
2010/0291,169 2010 Polyelectrolyte Complex for Imparting Antimicrobial Properties to a Substrate
7,790,217 2010 Method of attaching an antimicrobial cationic polyelectrolyte to the surface of a substrate
2009/0181,157 2009 METHOD OF ATTACHING AN ANTIMICROBIAL CATIONIC POLYELECTROLYTE TO THE SURFACE OF A SUBSTRATE
2008/0206,293 2008 Absorbent substrate with a non-leaching antimicrobial activity and a controlled-release bioactive agent.
Jugas
8 years ago
Polartec LLC uses Stay Fresh® on their blankets:
PolarCare™ Blankets
Polartec® PolarCare™ blankets are engineered specifically for the needs of today's professional textile services. These new blankets provide lighter, softer, and warmer comfort by combining our famous temperature regulating lofted fleece with Stay Fresh® antimicrobial treatment for longer lasting freshness
http://polartec.com/search/result/317a4ace2292743924d7b46b798704ba/
Stay Fresh® Antimicrobial
Stay Fresh® Antimicrobial is a breakthrough antimicrobial textile treatment technology under development for a broad range of applications, including healthcare textiles, commercial uniforms and essential wear.
Stay Fresh Antimicrobial is an EPA-registered product that offers material protection for a wide variety of applications, for which a range of solution concentrations are available. The range of application varies widely by intended use, durability requirement, and substrate material.
Stay Fresh Antimicrobial has excellent durability. It imparts durable antimicrobial activity to the surface of a wide variety of substrates. Stay Fresh Antimicrobial suppresses the growth of algae, mold, mildew, fungi and bacteria which cause unpleasant odors, discoloration, staining, deterioration and corrosion.
http://www.quickmedtech.com/technology/stay-fresh
Jugas
8 years ago
Is it possible that the float here is just 1,378,580? According to the last 10-k, that was put out in 2013, the OS was 37,346,154 as of June 30, 2013. On page 51 of that 10-k it shows insiders owning a total of 35,967,574, for a difference of 1,378,580. Furthermore, The OS had only increased by 100k shares from June 2011 to June 2013.
Jugas
8 years ago
Found this from 2013:
https://sbir.defensebusiness.org/content/static/selections/abs2012-2/dhpabs122.html
Quick Med Technologies, Inc.
902 NW 4th Street
Gainesville, FL 32601
Phone:
PI:
Topic#: (352) 379-0611
Bernd Liesenfeld
DHP12-016 Awarded: 5/13/2013
Title: Development of Technologies that Control Scar Contracture after Burn Injuries
Abstract: Current therapies to prevent scar formation and contracture of burns are minimally effective. QuickMed Technologies (QMT) proposes to develop an advanced therapy to enhance healing and prevent contraction of burn scars by combining the advanced prototype BURN- PLUS? dressing with Endoform? dermal template. BURN-PLUS is an occlusive island dressing with an adhesive apron bonded onto a super absorbent, microbicidal, pad that provides sustained release of two pre-loaded, FDA-cleared drugs: doxycycline and Kepivance?. Doxycycline is a broad spectrum antibiotic that also reduces inflammation through inhibition of tumor necrosis factor alpha (TNFa) converting enzyme (TACE) and inhibits contraction of collagen lattices by myofibroblasts through its inhibition of matrix metalloproteinases (MMPs). Kepivance is keratinocyte growth factor (KGF), which accelerates healing of skin wounds by directly stimulating proliferation and migration of epithelial cells. Endoform is a novel acellular matrix that has intact extracellular matrix (ECM) components (collagen IV, laminin, fibronectin) and growth factors (FGF2, VEGF) that increases vascularization and decreases irregular scar matrix in pig skin wounds. In this Phase I project, QMT will optimize design components of BURN-PLUS dressing and test its effectiveness alone and combined with Endoform matrix on enhancing healing and reducing scar formation and contracture of burn wounds in pigs.
Jugas
8 years ago
Found some interesting stuff on QMDT. They signed a licensing deal with a company called VIRIDIS BIOPHARMA PVT. LTD in 2010, and it looks like it's still on-going.
https://www.lawinsider.com/contracts/55sHYLC5gQ0rNazsFvLVdn/quick-med-technologies/florida/2010-07-30
I went to the VIRIDIS BIOPHARMA PVT. website, which is current, and look what I found under their products:
http://viridisbiopharma.com/index.htm
Microfoam™ and Woundguard™
These innovative dressings, available as a polyurethene foam (Microfoam™) or a 12 ply cotton gauze (Woundguard™), prevent bacterial penetration and inhibits growth within wound dressings. They are based on the cutting edge, patented non-leaching antimicrobial NIMBUS® Technology from Quick-Med Technologies, USA, which TIME magazine called one of the ‘10 Best Discoveries of 2006’. NIMBUS® is based on non-toxic, long chain polymers with high charge density that provide superior efficacy via a physical action on microbes. By destroying bacteria at the cellular level, NIMBUS® eliminates the risk of developing drug resistance. The technology is highly effective against a multitude of bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE).
http://viridisbiopharma.com/products/dressings.htm
And found this too:
Quick-Med Technologies
Quick-Med Technologies, Inc is a life sciences company focused on developing proprietary, broad-based technologies for infection prevention and control in the consumer and healthcare markets. They developed the patented NIMBUS® technology which is licensed by Viridis for the manufacture of Microfoam™ and Woundguard™.